Navigation Links
The Burnham Buzz, February 2009
Date:2/3/2009

Partnering for Progress

Burnham Institute for Medical Research (Burnham) has signed an assay development and license agreement with Johnson & Johnson Pharmaceutical Research and Development LLC. (J&JPRD). Under this multi-year agreement, Burnham will provide J&JPRD with access to high-throughput assay screening technologies to investigate certain drug targets for inflammatory diseases. The agreement is Burnham's first broad-based partnership with a large pharmaceutical company. Scientists at Burnham's Infectious and Inflammatory Disease Center are already using the institute's state-of-the-art robotic screening center in basic research programs.

Can you hear me now? Digital Drug Search

Giovanni Paternostro, M.D., Ph.D., and colleagues have developed a means to use search algorithms developed for the digital communications industry to identify drug combinations that are safe and effective. This novel approach involves algorithms that use biological measurements and model simulations to search for optimal drug combinations for the treatment of complex diseases such as cancer. In the study, a small subset of the drug combinations identified using the algorithms were tested in fruit fly and cancer cell model systems. Dr. Paternostro's research, published in the December 26, 2008 edition of PLoS Computational Biology, demonstrated that this approach can identify safe and effective drug combinations more rapidly that conventional methods. The conventional approach to finding drug combinations involves trial and error testing.

Gaining Control

Burnham scientists have identified the molecular machinery that regulates DNA replication and the S-phase checkpoint of the cell cycle. Wei Jiang, Ph.D., showed that the protein kinase complex known as Ddk is responsible for initiation of DNA replication, as well as controlling the S-phase of the cell cycle. If damaged DNA or a replication error is identified,
'/>"/>

Contact: Josh Baxt
jbaxt@burnham.org
858-795-5236
Burnham Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. Burnham researchers discover on switch for cell death signaling mechanism
2. The Burnham buzz
3. Burnham researchers turn cancer friend into cancer foe
4. Burnham researcher awarded $8 million grant
5. News from the February 2009 Journal of the American Dietetic Association
6. BioScience tip sheet, February 2009
7. February 2009 highlights from Biology of Reproduction
8. January-February GSA Bulletin media highlights
9. Media highlights for February in Biophysical Journal
10. Story tips from the Department of Energys Oak Ridge National Laboratory, February 2008
11. Highlights from the February 2008 Journal of the American Dietetic Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... Wallerian degeneration is a subject of major interest ... differentially regulated during the distinct stages of Wallerian ... differentiation and dedifferentiation. Although gene expression responses in ... peripheral nerve injury are known, differences in gene ... unclear. Dr. Dengbing Yao and co-workers from Nantong ...
(Date:7/30/2014)... cells can develop into a multitude of cells types. Researchers ... the specific types of mature cells that make up the ... key seems to be long chains of sugars that dangle ... at the University of California, San Diego, has created synthetic ... can be more easily manipulated to direct the process, they ...
(Date:7/30/2014)... map of the carbon stocks stored on land ... and improved methodology used to make the map ... economies. The new carbon map also reveals ... the critical input to studies of deforestation and ... purposes. The technique includes the determination of uncertainty ...
Breaking Biology News(10 mins):Peru's carbon quantified: Economic and conservation boon 2Peru's carbon quantified: Economic and conservation boon 3
... not be the first state that comes to mind. But it,s ... in Illinois and 1,500 acres of wine grapes. One acre ... though more commonly it,s $3,000 to $5,000. The largest wineries in ... 10,000 per year. "In many cases, growing wine grapes ...
... lacking access to clean, safe drinking water, scientists are ... new filtering technology that kills up to 98 percent ... A report on the technology appears in Nano ... Yi Cui and colleagues explain that most water ...
... new evidence that the fat tissue in those spare tires ... storage depot for surplus calories is an active organ ... perhaps increasing the risk of heart attacks, cancer, and other ... other substances not previously known to be secreted into the ...
Cached Biology News:Taming wild grapes for better wine 2Taming wild grapes for better wine 3
(Date:7/30/2014)... Mass. , July 30, 2014 /PRNewswire/ ... ), a biotechnology company focused on discovering, ... unmet medical needs using RNA-targeted technologies, today ... (RXI-109-1402) with RXI-109, for the reduction of ... revision surgery, has been initiated. ...
(Date:7/30/2014)... 30, 2014 Adding to their already ... boat special – Buy 2 of any Weighing ... will benefit lab technicians looking for durable and reliable ... ideal for multiple applications including weighing liquids, solid, or ... choices including diamond-shaped, hexagonal, square, aluminum weighing, and standard ...
(Date:7/29/2014)... “PharmaSphere: Emerging Biotech Investment Report Strategic ... report provides in-depth analysis of the current trends ... capital segments of the financial industry, bearing in ... impact on the future of emerging biotechnology companies ... identifies regions of the world that are attracting ...
(Date:7/29/2014)... 29, 2014 Human Longevity, Inc. (HLI), a ... on extending the healthy, high performance human life span, ... Ph.D., an expert in machine learning and machine translation ... HLI from Google where he was Distinguished Research Scientist ... directly to HLI Co-Founder and CEO, J. Craig ...
Breaking Biology Technology:RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 2RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 3RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 4RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars 5Weighing Boat Promotion Now Available at Pipette.com, Major Pipette Distributor 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 3Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 4Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 2Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 3
... CV Therapeutics,Inc. (Nasdaq: CVTX ) announced today ... up to $185 million in exchange for rights ... American sales of Lexiscan(TM),(regadenoson) injection. CV Therapeutics received ... receive a potential future milestone payment,of $10 million., ...
... and Families, EMERYVILLE, Calif., April 15 ... two new health care areas designed to,soothe patients ... to offer health resources. The Carol Ann,Read Breast ... procedures, all in one location, for the quickest ...
... April 15 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc.,(TSX: ONC, ... Dr. Anders,Kolb of the Nemours Center for Childhood ... Pediatric Sarcomas" was,presented today at the American Association ... being held in San Diego, California from,April 12-16, ...
Cached Biology Technology:CV Therapeutics Announces $185 Million Transaction with TPG-Axon Capital for Half of Royalty for Lexiscan(TM) (regadenoson) Injection 2CV Therapeutics Announces $185 Million Transaction with TPG-Axon Capital for Half of Royalty for Lexiscan(TM) (regadenoson) Injection 3Alta Bates Summit Medical Center Opens Two Warm, Supportive Patient Centers: Carol Ann Read Breast Health Center and Family Resource Center 2Alta Bates Summit Medical Center Opens Two Warm, Supportive Patient Centers: Carol Ann Read Breast Health Center and Family Resource Center 3Oncolytics Biotech Inc. Collaborators Present Reovirus Research for Pediatric Sarcomas at AACR Annual Meeting 2
... UltraClean GelSpin Kit utilizes a silica based spin ... After electrophoresis, the desired DNA band is cut ... the spin filter unit. The gel slice is ... Then the DNA is bound to the silica ...
...
Our Histology, Immunohistochemistry and tissue arrays services include samples processing, different type of staning, histollogical stains, image analysis, tissue arrays, immunohistochemistry, etc....
Mouse polyclonal antibody to GRID2 - glutamate receptor, ionotropic, delta 2...
Biology Products: