Navigation Links
The American Society for Microbiology honors William Hanage
Date:8/22/2012

William P. Hanage, Ph.D., Department of Epidemiology, Harvard School of Public Health, has received a 2012 ICAAC Young Investigator Award. Hanage is honored for his work studying the epidemiology and evolution of infectious disease. "Hanage has provided game changing tools and expertise in the pneumococcal field, first with MLST and now with whole genome sequencing, to reach into the world of the organism," explains Katherine O'Brien of Johns Hopkins Bloomberg School of Public Health. "His work has revealed ways in which the pathogen attempts to escape vaccine control. He is brilliant, innovative, and tangential in his thinking one of those rare people who can see connections where others do not."

Hanage graduated from the University of Bath, United Kingdom, with an undergraduate degree in Biochemistry. He went on to receive his Ph.D. from Imperial College London in the laboratory of Jonathan Cohen studying host microbial interactions, where he developed a passion for infectious disease research. After obtaining his Ph.D., Hanage worked in Brian Spratt's laboratory at the University of Oxford and later in the Department of Infectious Disease Epidemiology at the Imperial College London, studying the molecular epidemiology of bacterial pathogens. He joined the faculty at Harvard School of Public Health in 2010.

Over time, Hanage developed an interest in theoretical approaches to epidemiology to complement the molecular perspective gained from his formal education. He continues to combine empirical and theoretical methods in his research. "Hanage's research productivity throughout his career speaks to his creativity and ability to cross over between disciplines, pulling from one area of expertise to apply tools to another domain," says O'Brien. Especially interested in subjects that combine clinical importance with fundamental biological questions, Hanage looks at questions like how pathogens respond to novel selective pressures in the form of antimicrobials and vaccines. He has a specific interest in understanding the factors behind the response of the bacterial population to pneumococcal conjugate vaccination.

In addition to such clinically focused questions, Hanage has worked extensively on the phenomenon of homologous recombination in bacteria, which shuffles genetic material among lineages, studying how it can be detected and its consequences for how bacteria respond in the face of novel selective pressures. "He has developed new methods for data analysis and combining molecular and traditional epidemiology," says Stephen Pelton, Boston University Schools of Medicine and Public Health. Indeed, recombination or horizontal gene transfer makes the very notion of species problematic for bacteria, another of Hanage's major interests, one for which he was awarded a University Research Fellowship by the Royal Society. Hanage has also increasingly become involved with population genomic analyses of large numbers of very closely related pathogen isolates to probe in detail their patterns of transmission and diversification. His work on pathogen evolution was recognized with the 2012 Fleming Prize from the Society for General Microbiology. "Recently, Hanage has been among the pioneers of genomic epidemiology for bacterial pathogens. He exemplifies the combination of theoretical and experimental skills that will be fundamental to the future of infectious disease epidemiology," describes nominator Marc Lipsitch, Harvard School of Public Health.

"I believe Hanage's largest contributions have yet to come," says Pelton. "I think he will lead us to new insights into genetic regulation that permit specific clones of Streptococcus pneumoniae to successfully compete in the nasopharynx, to be more easily transmitted from person to person, and to evade host defenses to cause disease. I am confident that this will inform new approaches to treatment and disease prevention."

"Beyond his scientific accomplishments, for which his publication record speaks clearly, his personal and mentoring characteristics have to be emphasized," summarized O'Brien. "He is a gem of a colleagueenthusiastic, welcoming of collaborations, generous with his time toward students, and a genuine scholarly partner."


'/>"/>
Contact: Garth Hogan
ghogan@asmusa.org
American Society for Microbiology
Source:Eurekalert

Related biology news :

1. American College of Rheumatology releases first classification criteria for polymyalagia rheumatica
2. Common North American frog identified as carrier of deadly amphibian disease
3. UC research tests new tool to guide reintroduction of the American chestnut
4. American Society of Plant Biologists honors early career women scientists
5. Scripps Research Institute Professor Gerald F. Joyce elected to American Academy of Arts & Sciences
6. Professor known for work with hunter-gatherers elected to American Academy of Arts and Sciences
7. Elsevier selected as new publisher of the American Journal of Geriatric Psychiatry
8. New study published on fertility awareness among American university students
9. The American Society for Microbiology honors Ellen Jo Baron
10. Steve Fisher joins American Health IT LLC as VP of Operations
11. University of Tennessee anthropologists find American heads are getting larger
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)...   Neurotechnology , a provider of high-precision ... the release of the SentiVeillance 6.0 ... recognition using up to 10 surveillance, security and ... new version uses deep neural-network-based facial detection and ... a Graphing Processing Unit (GPU) for enhanced speed. ...
(Date:3/20/2017)... PMD Healthcare announces the release of its ... System (WMS), a remote, real-time lung health monitoring and ... is a Medical Device, Digital Health, and Chronic Care ... innovative solutions that empower people to improve their healthcare ... developed the first ever personal spirometer, Spiro PD, which ...
(Date:3/9/2017)... and MOUNTAIN VIEW, Calif. , March ... Made Simple," and 23andMe , the leading personal ... food choices.  Zipongo can now provide customers with personalized ... health goals and biometrics, but also genetic markers impacting ... Zipongo,s personalized food decision support platform uses ...
Breaking Biology News(10 mins):
(Date:3/22/2017)... 22, 2017  UBM and the Massachusetts Medical ... extended partnership and the third annual Massachusetts Medtech Week. ... 21 st Annual MassMEDIC Conference held in ... 3-4, 2017. MassMEDIC will feature ... President and CEO, Scott Whitaker , at ...
(Date:3/22/2017)... MarketNewsUpdates.com News Commentary  ... The traditional ways to ... as of late due to the rise of the opioid ... dramatic impact on patient,s quality of life as Biotech and ... new forms of opioid formulations that prevent abuse. Biotech and ...
(Date:3/22/2017)... , ... March 21, 2017 , ... Okyanos Cell Therapy ... as part of their live events series, “Stem Cell Therapy: The Next Phase in ... under the 2013 Stem Cell Research and Therapy Act, Okyanos maintains a ...
(Date:3/22/2017)... ... March 21, 2017 , ... ... its innovative Quantum peristaltic pump with patented ReNu single-use (SU) cartridge technology. ... standard for high-pressure feed pumps in SU tangential flow filtration (TFF), virus ...
Breaking Biology Technology: