Navigation Links
That which does not kill yeast makes it stronger
Date:1/29/2012

ng fluconazole, tunicamycin, or benomyl, when compared to euploid cells.

Interestingly, certain chromosome combinations dominated in colonies that were resistant to a specific drug. Fluconazole-resistant colonies typically gained an extra copy of chromosome VIII, tunicamycin-resistant colonies tended to lose chromosome XVI, while a majority of benomyl-resistant colonies got rid of chromosome XII. "This suggested to us that specific karyotypes are associated with resistance to certain drugs," says Chen.

Digging deeper, Chen grew tunicamycin-resistant yeast cells, which had adapted to the presence of the antibiotic by losing one copy of chromosome XVI, under drug-free conditions. Before long, colonies of two distinct sizes emerged. He quickly discovered that the faster growing colonies had regained the missing chromosome. By returning to a normal chromosome XVI number, these newly arisen euploid cells had acquired a distinctive growth advantage over their aneuploid neighbors. But most importantly, the fast growing yeast cells were no longer resistant to tunicamycin and thus clearly linking tunicamycin resistance to the loss of chromosome XVI.


'/>"/>

Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Which way did it go?
2. VTT identified specific bacteria which precede autoimmune diabetes
3. Which direction are herbicides heading?
4. Scientists discover 3 new gene faults which could increase melanoma risk by 30 percent
5. Climate change will show which animals can take the heat
6. Hormone predicts which kidney patients might die early
7. A mold on which to create new parts of the puzzle that is the nervous system
8. USC scientists uncover mechanism by which chronic stress causes brain disease
9. How ants tame the wilderness: Rainforest species use chemicals to identify which plants to prune
10. Biodiversity in danger: Which areas should be protected?
11. Insects hold atomic clues about the type of habitats in which they live
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... 8, 2014 You,ve been here before: you desperately ... remember your password, site key or the answer to your ... grade teacher? Today, Hoyos Labs , ... that will finally put an end to the frustration that ... . 1U leverages a user,s smartphone to acquire his ...
(Date:12/10/2014)... , Dec. 9, 2014  Wake Forest Baptist Medical ... building for its School of Medicine. Funding for this ... capital campaign that will be publicly launched next summer. ... located in the former 60 series R.J. Reynolds Tobacco ... Quarter. Construction will begin immediately with plans to be ...
(Date:12/10/2014)... , Dec. 08, 2014 Research and ... the addition of the "Biometrics Market in ... http://photos.prnewswire.com/prnh/20130307/600769 ... projects such as rural banking and upgradation of ... trends witnessed in the market. Besides the aforementioned ...
Breaking Biology News(10 mins):The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
... CHEONGJU, SOUTH KOREA--In the life cycle of plants, most ... such as germination, shade avoidance, circadian rhythms, and flower ... the use of LED lighting in plant and vegetable ... effects of these artificial lights on the growth and ...
... from the Baylor College of Medicine and the Texas Heart ... repair. The future goal is to use this knowledge ... heart attack. The research has just been published in the ... the team who uncovered the signaling pathway, called the Hippo ...
... faces of some primates contain so many different colors black, ... kinds of combinations and often striking patterns while other primate faces ... on the evolution of 129 primate faces in species from Central ... of 139 Old World African and Asian primate species that have ...
Cached Biology News:Researchers test effects of LEDs on leaf lettuce 2Breakthrough in adult heart repair 2Biologists find an evolutionary Facebook for monkeys and apes 2Biologists find an evolutionary Facebook for monkeys and apes 3Biologists find an evolutionary Facebook for monkeys and apes 4Biologists find an evolutionary Facebook for monkeys and apes 5
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... rose slightly, with 17,000 more jobs created in April. Though there was ... is off by about 40 percent compared to 2008. , ... Seattle, ... healthcare off by about 40 percent from first quarter 2008, job seekers ...
... OMAHA, Neb., May 22 Transgenomic, Inc. (OTC Bulletin ... Schuh, Ph.D. and Michael B. McNulty to its Board ... Executive Officer of Sorrento Therapeutics, Inc. (STI). STI ... antibody library construction technology, the STI technology, which applies ...
... software collects, manages and analyzes patient cases from across ... 21 US Oncology, Inc ., ... treatment and research network has been recognized as a ... (IDG) Computerworld Honors Program ...
Cached Biology Technology:The MedZilla Report: April 2009 Employment Outlook for Biotech/Pharma/Health 2The MedZilla Report: April 2009 Employment Outlook for Biotech/Pharma/Health 3Transgenomic, Inc. Announces Appointment of New Board Members 2Transgenomic, Inc. Announces Appointment of New Board Members 3US Oncology Named 2009 Laureate by IDG Computerworld Honors Program 2US Oncology Named 2009 Laureate by IDG Computerworld Honors Program 3US Oncology Named 2009 Laureate by IDG Computerworld Honors Program 4US Oncology Named 2009 Laureate by IDG Computerworld Honors Program 5
...
...
Rb anti-Occludin (C-term GST)...
... siRNA and miRNA Isolation Traditional ... recover mRNA and can result in the ... Ambions mirVana miRNA Isolation Kit purifies all ... and double-stranded. Through an enrichment procedure included ...
Biology Products: