Navigation Links
Texas Biomed reports faster, more economical method for detecting bioterror threats
Date:11/5/2012

Texas Biomedical Research Institute scientists in San Antonio have developed a faster, less expensive route to screen suitable tests for bioterror threats and accelerate the application of countermeasures.

The new process screens for pairs of affinity reagents molecular magnets that bind to and hold on to their targets, be they toxins, viruses or bacteria. That will enable countermeasures to be selected and utilized much faster than the current practice.

"Using crude extracts from E. coli, the workhorse bacterium of the biotechnology laboratory, the new route bypasses the need for purification and complex equipment, enabling screening to be performed in under an hour," said Andrew Hayhurst, Ph.D., a Texas Biomed virologist.

Normally, he said, such screening requires sophisticated costly equipment to purify and analyze the affinity reagents. Such analysis becomes a huge burden when hundreds of reagents need to be checked and can take weeks to months.

The process funded primarily by Texas Biomed and the San Antonio Area Foundation, and in part by the Defense Threat Reduction Agency and the National Institutes of Health (NIH) was described online in the November 5, 2012 issue of Nature Publishing Group's Scientific Reports.

"We need an inexpensive route to screen libraries of affinity reagents. It had to be simple and self-contained as we eventually needed it to work in the space-suit lab or hot zone," said Hayhurst.

His surprisingly simple scheme allows scientists to make stop-gap tests to any given biological threat in a matter of days, with the screening step completed in an hour. The goal now is to speed up the entire process to work within a single day.

Hayhurst initially developed the pipeline using llama antibodies as the affinity reagents to botulinum neurotoxins, known as the world's most poisonous poisons 100 billion times more toxic than cyanide and handled in a specialized biosafety cabinet at bios
'/>"/>

Contact: Joseph Carey
jcarey@txbiomed.org
210-258-9437
Texas Biomedical Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. SMU professor Louis Jacobs honored with prestigious award from Texas science teachers
2. EyeLock Inc. Brings High-Tech Iris Biometric Production to Texas
3. Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars
4. Controlling gait of horses may be possible, says key study from Texas A&M
5. BP Biofuels, Texas AgriLife Research sign agreement to advance biofuel feedstock development
6. NSBRI renews space life sciences graduate programs at MIT, Texas A&M
7. University of Texas Medical Branch selected to manage Center for Polar Medical Operations
8. Mining cleanup benefits from Texas A&M expertise
9. Diet of early human relative Australopithecus shows surprises, says Texas A&M researcher
10. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
11. NASA satellite measurements imply Texas wind farm impact on surface temperature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... Calif. , July 7, 2015  Based ... market, Frost & Sullivan recognizes Credence ID, LLC ... Entrepreneurial Company of the Year Award. Credence ... to aid in its mission of offering enrollment ... populations globally. As Credence ID was formed by ...
(Date:7/2/2015)... , June 25, 2015 ... addition of the "Next Generation Biometrics Market by ... 2020" report to their offering. The ... Billion by 2020, at a CAGR of 17.9% between ... the leading application for the market. Safran SA ...
(Date:6/30/2015)... , June 30, 2015 Genisphere ... as CEO to help further develop Genisphere,s therapeutics capabilities ... partnering experience, having spent much of the last 25 ... Amgen, Baxter Bioscience, and Johnson & Johnson. Tom started ... Technology and Biotech Corporate Finance. He graduated from Dartmouth ...
Breaking Biology News(10 mins):Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3
... 19, 2011) When researchers discovered the primary genetic defect ... up a new realm of research into treatment and a ... to clone the defective gene and study its effects in ... Chapel Hill have developed a technique for observing the defects ...
... presumably not lead to a permanent El Nio state ... drawn by an international team of researchers after it ... The growth rings of these fossils indicate that there ... during the last prolonged interglacial phase of the Earth,s ...
... a bidirectional relation between schizophrenia and epilepsy. The study ... the International League Against Epilepsy (ILAE), reports that patients ... develop schizophrenia and those with schizophrenia were close to ... Prior clinical studies have shown a prevalence of psychosis ...
Cached Biology News:The cellular intricacies of cystic fibrosis 250-million-year-old clam shells provide indications of future of El Nino phenomenon 2Study finds bidirectional relationship between schizophrenia and epilepsy 2
(Date:7/29/2015)... SAN FRANCISCO , July 29, 2015 /PRNewswire/ ... trialling mobile molecular testing for applications in food ... Ubiquitome,s hand-held, battery powered real-time PCR device, the ... the farm right through to the supermarket shelf ... world. This includes involvement in animal disease control ...
(Date:7/29/2015)... ... July 29, 2015 , ... ... announced its GHS Label Guide . To align chemical container labeling with ... guide includes explanations of label components, an example of an accurate label, and ...
(Date:7/29/2015)... 2015  Pfenex Inc. (NYSE MKT: PFNX) announced today ... released on Thursday, August 13, 2015, before the open ... will host a conference call to discuss the financial ... outlining the financial results and business update will be ... call 1-866-376-8058 (US) or 1-412-542-4131 (international) and reference Pfenex ...
(Date:7/29/2015)... /PRNewswire/ - RepliCel Life Sciences Inc. (OTCQB: REPCF) (TSX.V: ... to announce that the final design specifications of ... Prototypes for industrial and regulatory testing will now ... CE mark clearance to market the injector in ... (Photo: http://photos.prnewswire.com/prnh/20150729/248373 )  The ...
Breaking Biology Technology:AsureQuality and Ubiquitome Partner on Applications for Mobile Molecular Food Safety Testing 2Brady Announces a New GHS Label Guide 2Pfenex To Report Second Quarter 2015 Results and Provide Business Update on Thursday, August 13, 2015 2RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 2RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 3RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 4RepliCel Life Sciences Unveils Innovative Dermal Injector Prototype 5
... CAMBRIDGE, Mass., Oct. 1 Idenix Pharmaceuticals, Inc. (Nasdaq: ... discovery and development of drugs for the treatment of ... IDX184, the company,s lead hepatitis C development program, have ... of the American Association for the Study of Liver ...
... , Enerkem,s future biofuels plant ... , MONTREAL, Oct. 1 /PRNewswire/ - Enerkem, a leading waste-to-biofuels ... of a community energy initiative that will heat a Strathcona ... its process employed at its Edmonton waste-to-biofuels plant. , The ...
... QUEBEC CITY, Oct. 1 /PRNewswire-FirstCall/ - Medicago Inc. ... highly effective and affordable vaccines based on proprietary ... that it has initiated a Phase I human ... ("H5N1 vaccine"). Enrolment is ongoing and vaccination has ...
Cached Biology Technology:Idenix Announces Data Presentations at the 60th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) 2Idenix Announces Data Presentations at the 60th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) 3Enerkem Announces Unique Community Energy Project 2Medicago begins human clinical testing with its avian flu pandemic vaccine 2
... Ciphergen's ProteinChip arrays have been ... from biological samples. A variety of ... of proteins according to their unique ... different spots, allowing side-by-side sample comparison, ...
... have been developed for affinity capture ... variety of ProteinChip chemical surfaces allow ... their unique biochemical properties. Each chip ... sample comparison, and the chips are ...
... Use this kit to purify genomic DNA from plants ... bead beating in a deep well plate using large ... requires a high velocity plate shaker (available through Mo ... a silica membrane spin filter plate. The DNA is ...
... The DNA Engine instrument is ... Unprecedented thermal uniformity and ... and block-to-block. This rugged ... cycler, it's a platform for new ...
Biology Products: