Navigation Links
Texas A&M Researchers Examine How Viruses Destroy Bacteria

Viruses are well known for attacking humans and animals, but some viruses instead attack bacteria. Texas A&M University researchers are exploring how hungry viruses, armed with transformer-like weapons, attack bacteria, which may aid in the treatment of bacterial infections.

The Texas A&M researchers' work is published in the renowned journal Nature Structural & Molecular Biology.

The attackers are called phages, or bacteriophages, meaning eaters of bacteria.

The word bacteriophage is derived from the Greek "phagein," meaning eater of bacteria.

"The phages first attach to the bacteria and then inject their DNA," says Sun Qingan, coauthor of the article and a doctoral student at Texas A&M. "Then they reproduce inside the cell cytoplasm."

After more than 100 phage particles have been assembled, the next step is to be released from the bacterial host, so that the progeny virions can find other hosts and repeat the reproduction cycle, Sun adds.

Besides the cell membrane, the phages have another obstacle on their way out a hard shell called cell wall that protects the bacteria. Only by destroying the cell wall can the phages release their offspring.

But, don't worry. The phages have a secret weapon an enzyme that can destroy the wall from inside, thus called endolysin.

"One of the special examples, R21, remains inactive when it is first synthesized and attached to the membrane as demonstrated in our paper," Sun explains. "But when the enzyme leaves the membrane, it restructures just like a transformer and gains the power to destroy the cell wall."

The trigger controlling the transformation process is a segment of the enzyme call the SAR domain, according to the Texas A&M team.

"The SAR domain is like the commander it tells the enzyme when to begin restructuring and destroying the cell wall," he says. "This finding enables us to better understand the release process and provid

Contact: Sun Qingan
Texas A&M University

Page: 1 2

Related biology news :

1. Texas researchers and educators head for Antarctica
2. Ceres and Texas A&M to develop and market high-biomass sorghum for biofuels
3. Gulf of Mexico dead zone to be studied by University of Texas at Austin marine scientists
4. UT Southwestern scientist honored among best in Texas research
5. Rices West honored as one of Texas best researchers
6. Texas Hospital nations first to use large-scale cocoon strategy against whooping cough
7. Texas A&M testing oral contraceptives for animals
8. Texas A&M scientists say early Americans arrived earlier
9. Researchers confirm dead zone off Texas coast since 1985
10. Underwater microscope helps prevent shellfish poisoning along Gulf Coast of Texas
11. UTMB inventions win University of Texas System commercialization awards
Post Your Comments:
(Date:8/21/2014)... might seem easy to ignore, but they are the ... depend upon. Humans are increasingly dependent on algae, too, ... and sink it to the bottom of the ocean. ... laboratory experiments, researchers have evidence showing that viruses infecting ... algae,s blooms, even when all else stays essentially the ...
(Date:8/21/2014)... food intake, health and quality of life of older ... at the University of Waterloo receiving close to $1.5 ... Research (CIHR). , Professor Heather Keller, of the ... Schlegel research chair in nutrition and aging, will receive ... living in long-term care homes are poorly nourished. The ...
(Date:8/21/2014)... is a key region in the global oceanic circulation. "On ... warm Atlantic water flows to the north into the Arctic ... and sea ice push their way out of the Arctic ... water cools here on its way to the north and ... in this manner drives the global band of oceanic currents ...
Breaking Biology News(10 mins):Viruses take down massive algal blooms, with big implications for climate 2Grants will fund landmark aging research at Waterloo 2Arctic sea ice influenced force of the Gulf Stream 2Arctic sea ice influenced force of the Gulf Stream 3
... treatment and display heightened tumor-generating capacity can be identified by ... cells, a research team led by scientists at The University ... 3 edition of Cell Stem Cell . ... first time to separate low-PSA and high-PSA prostate cancer cells. ...
... Barbara, Calif.) More modest male displays attract the ... sexual selection theory, according to UC Santa Barbara researchers ... May 2 in the open access journal PLoS ... females should find more flamboyant displays the most sexually ...
... one factor that contributes to the overall rising cost ... utilization magnifies the cost burden associated with advanced imaging ... often provide the best clinical information for making a ... number of unnecessary studies are performed. Determining the rate ...
Cached Biology News:Scientists identify prostate cancer stem cells among low-PSA cells 2Scientists identify prostate cancer stem cells among low-PSA cells 3Scientists identify prostate cancer stem cells among low-PSA cells 4UCSB researchers find that less is more, for female cowbirds 2Radiologists study necessity of additional imaging recommendations in PET/CT oncologic reports 2
(Date:8/21/2014)... 2014 The College of New Rochelle ... in the Mid-Hudson Region to be designated as a ... applications from qualified “high-technology” businesses that align with the ... to have been selected for the START-UP NY program ... to stimulate economic development in New York by growing ...
(Date:8/21/2014)... Aug. 21, 2014 Mathematic studies at the ... , and funded by the Jeffrey Epstein VI Foundation ... can be visually identified for elimination. These aggressive cells are ... which shows a topological map of what to look for ... research, for while tumor cells can be extracted from biopsy, ...
(Date:8/21/2014)... HONG KONG , Aug. 21, 2014  China Cord ... today announced its plan to release financial results for ... August 28, 2014, after market close in the US.  ... call at 8:00 a.m. ET on Friday, August 29, ... brief overview of the Company,s recent developments, followed by ...
(Date:8/21/2014)... 2014 Pursuit Solutions ( ... and services for Life Sciences sales and marketing ... of New Commercial Sales Models” by Peter Robinson, ... The article examines some innovative models used to ... tested in the pharmaceutical market. Robinson grades the ...
Breaking Biology Technology:The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 3Science Power Jeffrey Epstein and Harvard University Fund Project to Visually Stop Tumor Growth 2China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2
... , , , SANTA ... America, Inc. (OTC Bulletin Board: CBAI), the umbilical cord blood ... rdblood-amer i ) focused on bringing ... and internationally, announced today the participation of its subsidiary CorCell ...
... 17, 2009 A UC Irvine center that aims to ... awarded $20 million over five years from the National Science ... of three NSF Centers for Chemical Innovation. Its scientists hope ... single molecules a feat that has proved elusive because ...
... BETHESDA, Md., Aug. 17 Spherix Incorporated (Nasdaq: SPEX ), an ... consulting services to food, supplement, biotechnology and pharmaceutical companies, today reported results for ... Recent and Upcoming Company Highlights , , ... Clinical trials on Naturlose (D-tagatose) as a treatment ...
Cached Biology Technology:Cord Blood America Announces Preferred Pricing for Blue Cross of Northeastern Pennsylvania Members 2UCI chemistry center awarded $20 million from NSF 2Spherix Reports Second Quarter 2009 Earnings 2Spherix Reports Second Quarter 2009 Earnings 3Spherix Reports Second Quarter 2009 Earnings 4Spherix Reports Second Quarter 2009 Earnings 5Spherix Reports Second Quarter 2009 Earnings 6Spherix Reports Second Quarter 2009 Earnings 7Spherix Reports Second Quarter 2009 Earnings 8
... Magnetofection technology, SilenceMag is the most ... rapid and easy to use, SilenceMag ... Specifically designed for siRNA delivery, SilenceMag ... low doses of siRNA.,SilenceMag formulation gives ...
... >95%NEN Radiolabeled Ligands\n\nReceptor-related research has long been ... radiolabeled ligands selected to keep pace with ... of products and services for receptor research ... radioligands. If you do not find exactly ...
Anti-WT-1 Liquid. In 10 μM PBS, 0.2 % BSA, pH 7.6. Recognizes the ~47-55 kDa Wilm's tumor protein in Wilm's tumor tissue. ...
... contains 400 unique human proteins on ... The proteins, a cross section of ... quadruplicate for high-quality results. Additional control ... guarantee high validity and reproducibility., ,UNIchip ...
Biology Products: