Navigation Links
Ten years on, Wellcome Trust launches study of 10,000 human genomes in UK
Date:6/24/2010

originally from Avon in southwest UK, followed from birth in 1991/2. The data for each group includes extensive description of their health and their development.

Studying this large group will help researchers build a near-complete catalogue of genetic variation in these 4,000 people. The depth of information recorded from them will provide a real opportunity to tie genetic variants to individual differences in health-related measurements. This should help identify the few thousand genetic variants amongst the 3 million each of us carries that are important in disease.

The information gathered from these 4,000 will be strengthened by the second component of 6,000 people, recruited by clinicians, who have a severe effect thought to have a genetic cause. These people have one of several conditions, including severe obesity, autism, schizophrenia and congenital heart disease. The gene-containing regions of their genomes known as 'exomes' which are likely to include the genetic variants important in their condition, will be analysed using new methods based in part on cutting-edge techniques developed at the Wellcome Trust Sanger Institute.

"We are fortunate in the UK to have such excellent collections of clinical samples provided by volunteers to help research and to help others," says Professor Tim Spector, who leads the TwinsUK study at King's College London. "10,000 volunteers have contributed to this, the largest genome sequencing project so far undertaken. It's a stunning commentary on the generosity of participants in UK studies."

The researchers point out that the results will have most immediate impact in genetics, contributing to an ongoing transformation of our understanding of human genetic variation. In some cases this may have direct clinical relevance. But more often it will lead to advance in medical science in understanding disease biology, which should, in time, reach through to medical applications.

'/>"/>
Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. First orchid fossil puts showy blooms at some 80 million years old
2. ESA celebrates 100 years of insect science journals
3. Researchers detect hint of oxygen 50 to 100 million years earlier than first believed
4. The benefits of 80 million years without sex
5. Researchers find origin of breathable atmosphere half a billion years ago
6. Fossil record reveals elusive jellyfish more than 500 million years old
7. Rodent fossils allows to determine climate of the Iberian Peninsula 6 million years ago
8. Atomic bomb survivor, scientists mark 60 years of long-term radiation study
9. Molecular Biology of the Cell celebrates 25 years of publication
10. 4 health behaviors can add 14 extra years of life
11. After more than 100 years apart, webworms devastate New Zealand parsnips
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD and ... focused on the growing mobile commerce market, announced today ... DISTRIBUTED VOICE DIRECTED PAYMENT METHOD AND SYSTEM. ... payment method. Payment accounts may be selected via voice ... if both the speech (the word associated with the ...
(Date:2/18/2015)... , Feb. 18, 2015  Cepheid (NASDAQ: CPHD ... the following conferences, and invited investors to participate via webcast. ... Boston, MA Tuesday, March 3, 2015 at 11.20 ... Orlando, FL Wednesday, March 4, 2015 ... To access the live webcasts for these events, please visit ...
(Date:2/12/2015)... Feb. 12, 2015   MedNet Solutions , ... clinical study management systems, has recently bolstered its ... distinguishing iMedNet as the ... (CROs) and healthcare consultants.  Building on the Program,s ... referrals and numerous co-marketing opportunities), MedNet,s new and ...
Breaking Biology News(10 mins):NXT-ID Patents Voice Directed Payments 2NXT-ID Patents Voice Directed Payments 3Cepheid to Webcast Upcoming Financial Presentations 2MedNet Solutions Announces Key Enhancements To Its iMedNet Partner Program 2
... Wayne State University researchers are testing a way to ... to healthier outcomes for mothers and their babies. ... Eunice Kennedy Shriver National Institute of Child Health and ... researchers will capture human fetal cells for genetic study ...
... flows in streams and rivers or on preserving only ... need a good mix of steep, cold-running streams and ... open for salmon adapted to reproduce better in one ... sort of varied landscape serves not just salmon, it ...
... available in German . Soil is ... incredible diversity, plants specifically choose certain species, give them access ... bacterial community from which they then benefit in a variety ... be able to tell which of these bacteria are friends ...
Cached Biology News:Wayne State researchers working to improve genetic analysis, disorder detection 2Bears, scavengers count on all-you-can-eat salmon buffet lasting for months 2Bears, scavengers count on all-you-can-eat salmon buffet lasting for months 3Bacterial community inside the plant root 2Bacterial community inside the plant root 3
(Date:2/26/2015)... 2015   Regulus Therapeutics Inc . (NASDAQ: ... and development of innovative medicines targeting microRNAs, today announced ... Chief Executive Officer of Regulus, will present a company ... Annual Healthcare Conference on Wednesday, March 4, 2015 at ... the Boston Marriott Copley Place.  The ...
(Date:2/26/2015)...  NuGene International, Inc. ("NuGene") (OTCQB: NUGN), the ... hair rejuvenation, has announced that it has selected ... investor relations and strategic communications. ... diversification strategies – and we need to communicate ... Ali Kharazmi CEO of NuGene when announcing this ...
(Date:2/26/2015)... February 26, 2015 Innovation is ... emerging from unexpected parts of the world and ... From agriculture to manufacturing to health care, disruption ... environmental realities and socio-political trends shake the foundations ... key ingredient for CEOs to survive the next ...
(Date:2/26/2015)... Feb. 26, 2015 Ceres, Inc . ... in Oracle PartnerNetwork. In attaining Gold Level membership, Ceres ... establish Oracle-related knowledge in delivering Ceres, Persephone genome visualization ... customers. Originally developed for in-house use by ... in and out of massive amounts of genetic data, ...
Breaking Biology Technology:Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 2Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 3NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 2NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 3One Million Acts of Innovation Canada Creates Partnership with The Economist Events’ Innovation Forum 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4
... NuMe Health LLC, a biotechnology company developing evidence-based ... disease status by modifying  the bacteria that live ... formation of its scientific advisory board (SAB). NuMe,s SAB ... the fields of nutrition, diabetes, obesity, health promoting ...
... 2011 , Spherix Incorporated (NASDAQ: ... therapy in diabetes, metabolic syndrome and atherosclerosis, and providers ... biotechnology and pharmaceutical companies – today announced the closing ... shares of its common stock together with warrants to ...
... 28, 2011 Nutra Pharma Corporation (OTCBB: NPHC), ... Multiple Sclerosis (MS), Human Immunodeficiency Virus (HIV/AIDS), Adrenomyeloneuropathy ... Executive Officer, Rik J. Deitsch, was interviewed by ... The interview provides an overview of the Company, ...
Cached Biology Technology:NuMe Health Advances its Cobiotics™ Technology With Addition of Scientific Advisory Board and Filing of Patent Application for First Product 2NuMe Health Advances its Cobiotics™ Technology With Addition of Scientific Advisory Board and Filing of Patent Application for First Product 3NuMe Health Advances its Cobiotics™ Technology With Addition of Scientific Advisory Board and Filing of Patent Application for First Product 4Spherix Announces Closing of Private Placement of $1.25 Million, Discusses Use of Proceeds 2Spherix Announces Closing of Private Placement of $1.25 Million, Discusses Use of Proceeds 3Nutra Pharma CEO Interviewed by Wall Street Reporter 2