Navigation Links
Ten years on, Wellcome Trust launches study of 10,000 human genomes in UK
Date:6/24/2010

originally from Avon in southwest UK, followed from birth in 1991/2. The data for each group includes extensive description of their health and their development.

Studying this large group will help researchers build a near-complete catalogue of genetic variation in these 4,000 people. The depth of information recorded from them will provide a real opportunity to tie genetic variants to individual differences in health-related measurements. This should help identify the few thousand genetic variants amongst the 3 million each of us carries that are important in disease.

The information gathered from these 4,000 will be strengthened by the second component of 6,000 people, recruited by clinicians, who have a severe effect thought to have a genetic cause. These people have one of several conditions, including severe obesity, autism, schizophrenia and congenital heart disease. The gene-containing regions of their genomes known as 'exomes' which are likely to include the genetic variants important in their condition, will be analysed using new methods based in part on cutting-edge techniques developed at the Wellcome Trust Sanger Institute.

"We are fortunate in the UK to have such excellent collections of clinical samples provided by volunteers to help research and to help others," says Professor Tim Spector, who leads the TwinsUK study at King's College London. "10,000 volunteers have contributed to this, the largest genome sequencing project so far undertaken. It's a stunning commentary on the generosity of participants in UK studies."

The researchers point out that the results will have most immediate impact in genetics, contributing to an ongoing transformation of our understanding of human genetic variation. In some cases this may have direct clinical relevance. But more often it will lead to advance in medical science in understanding disease biology, which should, in time, reach through to medical applications.

'/>"/>
Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. First orchid fossil puts showy blooms at some 80 million years old
2. ESA celebrates 100 years of insect science journals
3. Researchers detect hint of oxygen 50 to 100 million years earlier than first believed
4. The benefits of 80 million years without sex
5. Researchers find origin of breathable atmosphere half a billion years ago
6. Fossil record reveals elusive jellyfish more than 500 million years old
7. Rodent fossils allows to determine climate of the Iberian Peninsula 6 million years ago
8. Atomic bomb survivor, scientists mark 60 years of long-term radiation study
9. Molecular Biology of the Cell celebrates 25 years of publication
10. 4 health behaviors can add 14 extra years of life
11. After more than 100 years apart, webworms devastate New Zealand parsnips
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/5/2015)... August 5, 2015 Transparency Market ... Recognition Market - Global Industry Analysis, Size, Share, Growth, ... for facial recognition is forecast to reach US$ 2,671.8 ... demand for surveillance systems by civil and government agencies. ... crimes and terrorist activities across the globe that would ...
(Date:8/3/2015)... Synaptics, Inc. (Nasdaq: SYNA ), the ... members of the executive management team will present to ... Leadership Forum on Tuesday, August 11, 2015 at 1:00 ... the Sonnenalp Resort in Vail, CO. ... information. An audio webcast of the event will be ...
(Date:7/31/2015)... juillet 2015 La 10e Conférence internationale ... organisée par le BGI du 22 au 25 ... en Chine. La conférence célèbre son ... 2006, l,ICG est devenue l,une des réunions annuelles ... « omiques » et c,est aussi la plus dynamique, la ...
Breaking Biology News(10 mins):Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3
... lineage of primates, according to scientific gospel, social behavior ... food, territory and reproduction. , That may well be ... study researchers from the University of Wisconsin-Madison have found ... basic motivations to be with one another. What's more, ...
... University researchers are creating a technology that will allow ... inside living humans and animals and watch their bones ... and slither. , This high-resolution, high-speed imaging system ... and back injuries and help scientists understand the evolution ...
... in fruits and vegetables that had been thought to ... little or no value in that role, according to ... at Oregon State University. , However, these same compounds ... are quite different ?the body sees them as foreign ...
Cached Biology News:In young mice, gregariousness seems to reside in the genes 2In young mice, gregariousness seems to reside in the genes 3Bones in motion: Brown scientists to create new 3-D X-ray system 2Bones in motion: Brown scientists to create new 3-D X-ray system 3Studies force new view on biology of flavonoids 2Studies force new view on biology of flavonoids 3
(Date:8/28/2015)... , ... August 28, 2015 , ... Since the initial launch of FireflySci Inc. (FFS) ... humor and excellent customer service. Images such as the Fonz in a lab coat ... some flavor to the humdrum spectroscopy field. , FireflySci is proud to be ...
(Date:8/27/2015)... 2015 The National Necrotizing Fasciitis Foundation ... saved by doctors at Vanderbilt University Hospital in ... Pharmaceuticals and Dr. John Crew , director of ... Medical Center in Daly City, CA. ... approach, pioneered by Dr. Crew, that had previously saved ...
(Date:8/27/2015)... ... ... Inc. Magazine released its annual list of the 5,000 fastest-growing privately held companies ... three years through 2014. Being named to the Inc. 5000 list designates a company ... , “We are thrilled to make the Inc. 5000 list for 2015,” stated Tad ...
(Date:8/26/2015)... 2015 /PRNewswire/ - iCo Therapeutics ("iCo" or "the Company") ... for the quarter ended June 30, 2015. Amounts, ... and presented under International Financial Reporting Standards ("IFRS"). ... to our Oral Amp B program, rapidly advancing ... Andrew Rae , President & CEO of ...
Breaking Biology Technology:Cuvette Manufacturer FireflySci Launches Back to School Deals with Complimentary Shipping On All Orders 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3iLab Solutions Named to 2015 Inc. 5000 List 2iLab Solutions Named to 2015 Inc. 5000 List 3iCo Therapeutics Announces Second Quarter 2015 Financial Results 2iCo Therapeutics Announces Second Quarter 2015 Financial Results 3
... Regulated Pharmaceutical Industry, LOS GATOS, Calif., ... (Signatures and Authentication for Everyone) BioPharma Association,Vendor ... of the SAFE,standards through the company,s user ... operate on TriCipher,Armored Credential System (TACS), the ...
... Maven Biotechnologies, LLC,an early stage biotechnology company ... announced that the company will,deliver a presentation ... Diego,California. Jeffrey C. Travis, Ph.D., Maven,s President ... 2007 at 3:30 PM. About Maven ...
... WikiAnswers Q&A ... Community, ... for National,Breast Cancer Awareness Month, Answers.com,s question and answer community,WikiAnswers(TM), is ... survivors,friends and family have gathered to ask questions and share their ...
Cached Biology Technology:TriCipher Joins SAFE BioPharma Association Vendor Partner Program 2Maven Biotechnologies, LLC to Present at BIOCOM Investor Conference 2Answers.com's WikiAnswers Supervisors Rallying for National Breast Cancer Awareness Month 2Answers.com's WikiAnswers Supervisors Rallying for National Breast Cancer Awareness Month 3
... EnzChek Pyrophosphate Detection Kit,provides a fast, ... the inorganic pyrophosphate (PPi ) produced,by ... as DNA and,RNA polymerizations, cyclic AMP ... the enzymatic activation of fatty acids ...
...
... PCR specificity *High PCR specificity ... with unique QIAGEN PCR Buffer ... by the stringent built-in hot start ... Mix and simple reaction setup at ...
... proteins (NMPs) make up the internal structural framework ... functions as DNA replication, RNA synthesis, and hormone ... shown to be highly insoluble in vitro ... releases soluble nuclear matrix proteins that can be ...
Biology Products: