Navigation Links
Telltale moss
Date:9/29/2009

Hikers know that moss on a tree trunk always points north. According to new research by Israeli and German scientists, this ancient plant may also provide a new "compass" for stem cell research, telling scientists how better to program stem cells for medical purposes.

Dr. Nir Ohad of Tel Aviv University's Department of Plant Sciences and Prof. Ralf Reski of the University of Freiburg have discovered a new use for the Polycomb group proteins (PcG) found in moss. They reported their findings recently in the journal Development. PcG proteins play an important role in telling stem cells how to develop, they believe. The research is being funded by the German-Israeli Foundation.

Moss is a kind of plant that shares basic development processes with those found in humans. "We may not have found the switch that turns stem cells into tissue," comments Dr. Ohad, "but we have found a key component which makes this switch work."

Stopping the runaway gene

In their new paper, the researchers describe an ancient mechanism that alters the way DNA organizes inside the cell nucleus, which in turn, affects gene expression. This finding has important implications in stem cell therapies, which can go awry if implanted stem cells aren't reprogrammed properly.

The researchers examined the "central regulatory function" of the PcG complex and how it programs an organism's development, including the first divisions of cells as a new organism is born. Insights from this research have implications for plant and human development alike, and with time could be applied to cancer research. "As far as we know, there are some instances in cancer where the cellular mechanisms are defective or impaired," Dr. Ohad says. "When this happens, it can lead to the misregulation of the genetic code, which can then lead to the breakdown of a healthy cell."

He adds that this "switch," which ensures the proper development of the organism, emerg
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert

Page: 1 2

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... abandoned each year in U.S. waters and become what ... fish, crabs, and other species such as turtles. These ... watermen who depend on the resources--losses that are largely ... The report, published in the Marine Pollution Bulletin ... the derelict fish trap problem, and so-called "ghost fishing," ...
(Date:8/27/2014)... A growing number of studies have shown ... the pathogenesis of Parkinson,s disease. Previous studies ... Medical University in China have shown that ... injury, reduced divalent metal transporter 1 expression, ... substantia nigra of rotenone-induced Parkinson,s disease rats. ...
(Date:8/27/2014)... University of Adelaide research has shown that piglets can ... birthing frequency. , The outcome of the study at ... Animal Reproduction Science , is an important finding for ... welfare without loss of production. , "Sows don,t usually ... on heat after their piglets have been weaned," says ...
Breaking Biology News(10 mins):NOAA's Marine Debris Program reports on the national issue of derelict fishing traps 2Piglet weaning age no bar to litter frequency 2
... be your response to a radiological incident? How will your State ... us? How do we even know if we are exposed to ... 42nd Midyear Topical Meeting of the Health Physics Society (HPS), which ... at the Henry B. Gonzales Convention Center. The topic is "Recent ...
... groups including the mentally ill, the disabled and ... fare worse than others in the aftermath of natural ... Now, a new study by UCLA researchers ... terrorism-related fears and make more behavioral changes based on ...
... month, the City of Newark, Delaware became the first ... to store and provide power for the local electric ... alone, is specifically designed to store energy and improve ... concept, called Vehicle-to-Grid (V2G). With the City of Newark,s ...
Cached Biology News:42nd Mid-year Topical Meeting of the Health Physics Society 2Disabled and other vulnerable groups more susceptible to terrorism fears 2City of Newark first in nation using cars to power grid 2
(Date:8/27/2014)... TX (PRWEB) August 27, 2014 The ... and in-depth study on the current state of the ... report provides a basic overview of the industry, including ... and Chinese domestic market analysis are provided with a ... the market. A comparison between the international and Chinese ...
(Date:8/27/2014)... , Aug. 27, 2014  A novel biomarker ... help physicians better identify early-stage disease, when treatment ... according to a new study in The Journal ... (NYSE: DGX ) and other institutions ... protein outperformed conventional antibody-serum testing, including rheumatoid factor ...
(Date:8/27/2014)... Flagship Biosciences LLC, a leading provider of ... and medical device industries, has announced a laboratory and ... has consolidated its histology and tissue analysis operations from ... just north of Denver. The new addresses are: ... Suite 100, Westminster, CO 80021 , Tissue Image Analysis ...
(Date:8/27/2014)... Aug. 27, 2014 Tris Pharma, a specialty ... today announced that it has been selected as an ... Association,s 2014 Awards for Excellence competition in ... independent panel of judges from SCORE (Counselors to America,s ... will be honored at a gala event to be ...
Breaking Biology Technology:Trifluoroacetic Acid Industry (Asia, Europe, North America, ROW) Analysis Report Now Available at ReportsnReports.com 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 3Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 4Flagship Biosciences Announces Relocation and Expansion 2Tris Pharma Selected as an award winner in the New Jersey Business & Industry Association's 2014 Awards for Excellence 2
... , ... throughout all industries, which were once inspected with vision and or touch-probe, will now ... critical to batch production with tight tolerance levels which can now be easily monitored ... ...
... ... recruitment strategies. CenterWatch discusses tips to leverage online resources to enhance patient recruitment rates at ... ... study volunteers, the Internet is rated as one of the top ways patients learn about ...
... Md. , Jan. 12 Novavax, Inc. (Nasdaq: ... a pre-clinical safety and efficacy study of its RSV vaccine ... to support an Investigational New Drug (IND) application to advance ... candidate into clinical development.  This vaccine candidate is composed of ...
Cached Biology Technology:Nanometer Online Inspection With Nanovea 3D Non-Contact Profilometer 2CenterWatch to Address Importance of Web Use to Boost Patient Recruitment Rates 2CenterWatch to Address Importance of Web Use to Boost Patient Recruitment Rates 3NOVAVAX Announces Positive Preclinical Results for its Respiratory Syncytial Virus (RSV) Vaccine Candidate 2NOVAVAX Announces Positive Preclinical Results for its Respiratory Syncytial Virus (RSV) Vaccine Candidate 3NOVAVAX Announces Positive Preclinical Results for its Respiratory Syncytial Virus (RSV) Vaccine Candidate 4NOVAVAX Announces Positive Preclinical Results for its Respiratory Syncytial Virus (RSV) Vaccine Candidate 5
... in Tris buffer, pH 10.2 give activity ... system. Assays in diethanolamine buffer, pH 9.8 ... glycine buffer system. Protein determined by Biuret ... salts Preparation Unit Definition: One unit will ...
... traps a wide variety of solvent vapors that can ... flask (GCF400) allows for the collection of liquid into ... time minimizes waiting period., Ultra low -104 ... , Digital Display of ...
... Trap is specifically designed for efficient ... as DMSO and DMF in the ... refrigeration system set at -5 o ... DMSO, while completely eliminating the risk ...
Thermo Forma provides an array of accessory Racks for the Cryo/CryoPlus 16" Diameter storage system. To maximise inventory capacity a Jumbo Arrowhead configuration is recommended. You may choose betw...
Biology Products: