Navigation Links
Team shows how the honey bee tolerates some synthetic pesticides
Date:7/20/2011

CHAMPAIGN, Ill. A new study reveals how enzymes in the honey bee gut detoxify pesticides commonly used to kill mites in the honey bee hive. This is the first study to tease out the precise molecular mechanisms that allow a pollinating insect to tolerate exposure to these potentially deadly compounds.

The findings appear in the Proceedings of the National Academy of Sciences.

Previous studies have shown that honey bee hives are contaminated with an array of agricultural chemicals, many of which the bees themselves bring back to the hive in the form of contaminated pollen and nectar, said University of Illinois entomology professor and department head May Berenbaum, who led the new research.

"There are agricultural pesticides everywhere," she said. "They accumulate in the wax of bee hives, so bees in particular are exposed. And their habit of foraging very broadly across a staggering diversity of plant species also tends to expose them to many different types of habitats, which may also have different types of chemical residues."

Other chemicals are applied directly to the hives, she said. For the past 20 years, beekeepers have used acaricides chemicals designed to kill mites but not bees in the hive.

While evidence so far does not support the idea that exposure to synthetic pesticides is a cause or significant contributor to colony collapse disorder, the massive die-off of honey bees first reported in late 2006, "it's abundantly clear that pesticides aren't really very good for any insect," Berenbaum said. "So we figured it was about time somebody knew something about how pollinators process toxins."

The researchers focused on cytochrome P450s, enzymes that are well-known agents of detoxification "in most air-breathing organisms," Berenbaum said. Other studies had shown that cytochrome P450s in honey bees play a key role in their tolerance of pyrethroid pesticides, such as tau-fluvalinate, which is used to kill mites in the hive. But no previous study had identified specific cytochrome P450s in bees or in other pollinating insects that contribute to pyrethroid tolerance, Berenbaum said.

In a series of experiments, the team identified three cytochrome P450s in the honey bee midgut that metabolize tau-fluvalinate. They discovered that these enzymes also detoxify coumaphos, a structurally different organophosphate pesticide that also is used to kill mites in bee hives.

"This suggests that these honey bee cytochrome P450s are not particularly specialized," Berenbaum said. "That raises the possibility that a nontoxic dose of tau-fluvalinate may become toxic if an enzyme that is principally involved in its detoxification is otherwise occupied with a different chemical."

The evidence also suggests that honey bees were "pre-adapted" to detoxify pyrethroid pesticides, Berenbaum said. Pyrethroids are similar in structure to naturally occurring defensive compounds, called pyrethrins, produced by some flowering plants. Honey bees have likely had a long history of contact with pyrethrins, which are found even in some flowers in the daisy family. It appears that the same enzymes that helped the honey bees detoxify the pyrethrins in nature may also help them tolerate this relatively new pesticide exposure.

The new findings should enhance efforts to develop mite control methods that are even less toxic to bees, Berenbaum said.


'/>"/>

Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

Related biology news :

1. Long-term study shows effect of climate change on animal diversity
2. New approach to treating cystic fibrosis lung infection shows promise
3. Research shows Brazilian acai berry antioxidants absorbed by human body
4. Wildfires cause ozone pollution to violate health standards, new study shows
5. New CU-Boulder study shows diversity decreases chances of parasitic disease
6. U of MN study shows link between gene variations and cancer survival
7. New study shows drinking your vegetables may be a solution to bridging the vegetable gap
8. Mounting evidence shows health benefits of grape polyphenols
9. Research shows that the pill does not deserve its reputation for causing weight gain
10. New journal shows half-broken gene is enough to cause cancer
11. Research shows that time invested in practicing pays off for young musicians
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Team shows how the honey bee tolerates some synthetic pesticides
(Date:4/5/2017)... YORK , April 5, 2017 Today ... is announcing that the server component of the HYPR ... known for providing the end-to-end security architecture that empowers ... HYPR has already secured over 15 million ... makers including manufacturers of connected home product suites and ...
(Date:3/30/2017)... March 30, 2017 The research team of ... three-dimensional (3D) fingerprint identification by adopting ground breaking 3D fingerprint minutiae ... realm of speed and accuracy for use in identification, crime investigation, ... cost. ... A research ...
(Date:3/24/2017)... The Controller General of Immigration from Maldives Mr. Mohamed ... received the prestigious international IAIR Award for the most innovative high security ... ... Maldives Immigration Controller General, ... picture on the right) have received the IAIR award for the "Most ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... Massachusetts (PRWEB) , ... May 23, 2017 , ... ... making a splash at this year’s Bio-IT World Conference and Expo in ... Smart Data Lake® 4.0 solution. The Anzo Smart Data Lake is also a ...
(Date:5/22/2017)... Maryland (PRWEB) , ... May 22, 2017 , ... ... Olsen, joined with other leaders of the Maryland Biohealth community in developing and ... globally recognized Top 3 U.S. BioHealth Innovation Hub by 2023. ...
(Date:5/21/2017)... ... 20, 2017 , ... CNSDose is a genetically driven, clinically ... by finding the right antidepressant faster. CNSDose speeds recovery and reduces side ... personalized approach to treatment. , A peer-reviewed and published, 12-week double-blind ...
(Date:5/18/2017)... Mass. (PRWEB) , ... May 18, 2017 , ... ... the procedure on April 28, 2017 at the Prince Of Wales Private Hospital. ... cervical disc at level C6-C7. The patient failed conservative treatments prior to undergoing ...
Breaking Biology Technology: