Navigation Links
Team probes mysteries of oceanic bacteria
Date:3/3/2008

ples from the waters off Hawaii, in a part of the ocean known as the North Pacific Gyre.

Each liter of ocean water they collect contains up to a billion bacterial cells. For several years, researchers have been sequencing the DNA found in those bacteria, creating large databases of prevalent marine microbial genes found in the environment.

However, those DNA sequences alone cannot reveal which genes the bacteria are actually using in their day-to-day activities, or when they are expressing them.

Its a lot of information, and its hard to know where to start, said DeLong. How do you know which genes are actually important in any given environmental context?

To figure out which genes are expressed, DeLong and colleagues sequenced the messenger RNA (mRNA) produced by the cells living in complex microbial communities. mRNA carries instructions to the protein-building machinery of the cell, so if there is a lot of mRNA corresponding to a particular gene, it means that gene is highly expressed.

The new technique requires the researchers to convert bacterial mRNA to eukaryotic (non-bacterial) DNA, which can be more easily amplified and sequenced. They then use sequencing technology that is fast enough to analyze hundreds of millions of DNA base pairs in a day.

Once the sequences of highly expressed mRNA are known, the researchers can compare them with DNA sequences in the database of bacterial genes and try to figure out which genes are key players and what their functions are.

The team found some surprising patterns of gene expression, DeLong said. For example, about half of the mRNA sequences found are not similar to any previously known bacterial genes.


'/>"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Comet probes reveal evidence of origin of life, scientists claim
2. Studying component parts of living cells with carbon nanotube cellular probes
3. New MIT tool probes brain circuits
4. Astronomy technology brings nanoparticle probes into sharper focus
5. Shuttle brings space-grown strep bacteria back for study
6. The worlds oldest bacteria
7. Bacteria from sponges make new pharmaceuticals
8. Boston University biomedical engineers find chink in bacterias armor
9. University of Leicester scientists discover technique to help friendly bacteria
10. Spaceflight shown to alter ability of bacteria to cause disease
11. A tiny pinch from a z-ring helps bacteria cells divide
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB ... Good Clinical Practices (GCP) audit to confirm its ... (FDA) regulations. This accomplishment enables HITLAB to conduct ... utilizing the highest principles for patient safety and ... improve global healthcare access, quality, and delivery with ...
(Date:12/17/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ) ... Chemical Sensor Market 2015-2019" report to their ... One major trend upcoming in this ... in biomedical applications. Chemical sensors help in recording ... during surgical procedures. The Global Chemical Sensor market ...
(Date:12/15/2014)... Dec. 12, 2014 Research and Markets ... of the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition ... individuals. Facial recognition system measures the overall facial ... edges, mouth, and the distance between eyes. Facial ...
Breaking Biology News(10 mins):HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
... San Diego Cytori Therapeutics (NASDAQ: CYTX) announced ... from APOLLO, the Company,s European clinical trial evaluating ... with acute myocardial infarction (heart attack or AMI), ... the American College of Cardiology . The APOLLO ...
... of which are preventable via vaccines readily available in the ... of death for children in sub-Saharan Africa. ... funded by a $5.8 million grant aims to help prevent ... vaccine use and development. Funded by the Bill & Melinda ...
... the causes of the obesity epidemic in Aboriginal children ... factors that shape the Aboriginal community. A review article ... emphasizes that early childhood obesity prevention efforts should begin ... on breastfeeding initiatives and nutrition in the early childhood ...
Cached Biology News:Adipose stem cell heart attack trial data published in JACC 2$5.8 million Gates grant targets child-killing bacteria diseases in Africa 2
(Date:12/24/2014)... AUSTIN, Texas , Dec. 24, 2014 /PRNewswire/ ... company focused on gynecologic disease, announced today that ... with investors including Oracle Investment Management, Jack ... Vermillion directors. Total proceeds were $10.5 million, before ... working capital and general corporate purposes. ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 ... series is designed to introduce cutting edge ... users and partners of platform upgrades. This ... benefits; empowering users in their quest to ... tools. , According to SoundConnect’s Marketing Manager, ...
(Date:12/24/2014)... The report expects global cell isolation and ... also provides a carefully analyzed data about the vital ... market. , Full Copy of Report @ http://bit.ly/1yUxy0T ... for cell expansion will keep witnessing growth at an ... to be driven by rapid technological advancements, government funding ...
(Date:12/24/2014)... Sigma-Aldrich Corporation (NASDAQ: SIAL ... the Hart-Scott-Rodino Antitrust Improvements Act (HSR Act) in ... 2014, thereby completing the U.S. HSR Act antitrust ... the Company by Merck KGaA, Darmstadt, Germany.  ... to closing the transaction, which remains subject to ...
Breaking Biology Technology:Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3
... that it has received orders for the sale of ... far in its initial sales push,being led by new ... current efforts, shall announce such sales as and,when they ... an award-winning life sciences company focused on,the monitoring and ...
... 20 AMDL, Inc. (Amex:,ADL), headquartered in ... Jilin, China, through its wholly owned subsidiary ... company that,engages in the development, manufacture and ... announced today that JPI has a,new product ...
... Pharmaceuticals,Inc. (NASDAQ: ANPI , TSX: ANP), a global ... in the UBS Global Life,Sciences Conference, which is being ... On Monday, September 24, 2007 at 8:30am ET, Dr. ... give a 25-minute,presentation. A link to the live ...
Cached Biology Technology:Signalife Achieves $1.98 Million Sales Orders Thus Far 2AMDL's Jade Pharmaceutical Subsidiary Announces New Product Strategy; Six New Products, Including One With Sales Projected at Upwards of $10 Million, Under Development 2Angiotech to participate in UBS Global Life Sciences Conference 2Angiotech to participate in UBS Global Life Sciences Conference 3
... electrophoresis into an automated, high-throughput operation with ... system is ideal for analyzing multiple PCR ... Fully automated, robot-compatible, and ready to put ... your high-throughput screening assignments as easy as ...
...
SpectroQuest single beam 4nm UV/Vis spectrophotometer; stand-alone unit; large angled LCD screen; large sample compartment...
Fluorescence Preserving Media, 100 mL...
Biology Products: