Navigation Links
Team of UC scientists awarded $2 million NIH grant for better flu diagnoses
Date:6/16/2010

Researchers at the University of Cincinnati have received a five-year grant to develop rapid, robust, user-friendly diagnostics for influenza virus.

An interdisciplinary team of scientists has received a $2.3 million dollar grant from the National Institute for Allergy and Infectious Diseases, one of the National Institutes of Health (NIH). The name of the grant is "Glycan Receptor Mimics for Rapid Detection, Typing, and Susceptibility Testing of Influenza."

With the five-year grant, the team will develop carbohdyrate-based diagnostics for influenza virus. The principal investigators on the grant are Suri S. Iyer, an assistant professor in the Chemistry Department of the McMicken College of Arts and Sciences, and Alison A. Weiss, a professor of molecular genetics in UC's College of Medicine. Also on the team are Monica McNeal and Mary Staat from Cincinnati Children's Hospital Medical Center.

Iyer's lab specializes in a type of carbohydrate called a glycoconjugate that eventually can be used as a means of detecting the presence of toxins. The carbohydrates "recognize" the toxins on a surface, react and cause something to change like the color of a solution, which could be read by a measuring device, for example. In this way, the carbohydrates are called a "recognition molecule."

Through the grant, the scientists will synthesize a library of tailored carbohydrates. They will then incorporate these synthetic molecules into multiple diagnostic platforms and evaluate their performance to detect influenza using clinical human samples. As in their other collaborations, Iyer's research group will create the molecules in their lab that then go to Weiss' lab to be tested.

Successful completion of this project is expected to lead to the development of rapid, robust, user-friendly diagnostics for influenza virus.

"It is really exciting to find solutions to basic problems in infectious diseases," says Weiss. "Such advances require an interdisciplinary approach. Our team consists of synthetic chemists, microbiologist and clinicians."

"Early and accurate detection of influenza strains is critical for effective countermeasures, especially since new strains for example, the 2009 H1N1 strain can spread rapidly," says Iyer. "There is an urgent need to develop diagnostics to detect and type the particular strain and we are excited to work on this problem."


'/>"/>

Contact: Wendy Beckman
wendy.beckman@uc.edu
513-556-1826
University of Cincinnati
Source:Eurekalert  

Related biology news :

1. UK scientists working to help cut ID theft
2. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
3. Comet probes reveal evidence of origin of life, scientists claim
4. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
5. Male elephants get photo IDs from scientists
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis
8. Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs
9. Clemson scientists shed light on molecules in living cells
10. Scientists tackle mystery mountain illness
11. T. rex quicker than Becks, say scientists
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Team of UC scientists awarded $2 million NIH grant for better flu diagnoses
(Date:5/6/2017)... RAM Group , Singaporean based ... in biometric authentication based on a novel  ... to perform biometric authentication. These new sensors are based on ... Ram Group and its partners. This sensor will have ... and security. Ram Group is a next generation ...
(Date:4/19/2017)... The global military biometrics market ... by the presence of several large global players. The ... major players - 3M Cogent, NEC Corporation, M2SYS Technology, ... 61% of the global military biometric market in 2016. ... military biometrics market boast global presence, which has catapulted ...
(Date:4/17/2017)... April 17, 2017 NXT-ID, Inc. (NASDAQ: ... the filing of its 2016 Annual Report on Form 10-K on ... ... is available in the Investor Relations section of the Company,s website ... SEC,s website at http://www.sec.gov . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... A ... pregnancy rates in frozen and fresh in vitro fertilization (IVF) transfer ... age to IVF success. , After comparing the results from the fresh and ...
(Date:10/10/2017)... Poway, California (PRWEB) , ... October 10, 2017 , ... ... afternoon speaking at his local San Diego Rotary Club. The event ... San Diego, CA and had 300+ attendees. Dr. Harman, DVM, MPVM was joined ...
(Date:10/9/2017)... Oct. 9, 2017  BioTech Holdings announced today ... which its ProCell stem cell therapy prevents limb ... The Company, demonstrated that treatment with ProCell resulted ... saved as compared to standard bone marrow stem ... resulted in reduction of therapeutic effect.  ...
(Date:10/7/2017)... Phoenix, Arizona (PRWEB) , ... ... ... than 15 years’ experience providing advanced instruments and applications consulting for microscopy ... the in-house expertise in application consulting, Nanoscience Analytical offers a broad range ...
Breaking Biology Technology: