Navigation Links
Team led by Scripps Research scientist identifies new gene for memory
Date:9/8/2010

JUPITER, FL, September 8, 2010 A team led by a Scripps Research Institute scientist has for the first time identified a new gene that is required for memory formation in Drosophila, the common fruit fly. The gene may have similar functions in humans, shedding light on neurological disorders such as Alzheimer's disease or human learning disabilities.

The study was published in the September 9, 2010 edition (Vol. 67, No. 5) of the journal Neuron.

"This is the first time we have a new memory and learning gene that lies outside what has been considered the most fundamental signaling pathway that underlies learning in the fruit fly," said Ron Davis, chair of Scripps Research Department of Neuroscience who led the study. "Since many of the learning and memory genes originally identified in the fruit fly are clearly involved in human neurological or psychiatric diseases, this discovery may offer significant new insights into multiple neurological disorders. We're definitely in the right ballpark."

The study shows that different alleles or mutant forms of the gene, known as gilgamesh (gish), are required for short-term memory formation in Drosophila olfactory associative learning learning that links a specific odor with a negative or positive reinforcer.

Because Drosophila learning genes are known to be conserved in higher organisms including humans, they often provide new insights into human brain disorders. For example, the Drosophila gene known as dunce, which Davis helped identify several years ago, provided clues to the genetics of the devastating psychiatric condition of schizophrenia. Recent studies have revealed that the human version of the dunce gene is a susceptibility determinant for schizophrenia. In a similar way, any new learning gene identified in Drosophila, including gilgamesh, may provide new clues to genes involved in human neurological or psychiatric disorder
'/>"/>

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Seafood stewardship questionable: UBC-Scripps experts
2. UCI-Scripps study links cellular motors to memory
3. Scripps Research scientists uncover new mechanism of memory formation
4. Scripps Oceanography biologists awarded prestigious honors
5. Scripps Research scientists uncover possible cocaine addiction trigger
6. Scripps research study opens the door to new class of drugs for epileptic seizures
7. Scripps research study shows infectious prions can arise spontaneously in normal brain tissue
8. Scripps Research scientists find new way to attack cancerous cells
9. Scripps research scientists determine structure of immune molecule that counteracts HIV strains
10. Scripps Research scientists break barrier to creating potential therapeutic molecules
11. Team led by Scripps Research scientists discovers bodys own molecular protection against arthritis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... 2014--Sea monkeys have captured the popular attention of both ... life cycle -- sold as dehydrated eggs, these tiny ... more than a tank of salt water. , ... other zooplankton, brine shrimp vertically migrate in large groups ... the surface at night and retreating deeper during the ...
(Date:9/30/2014)... team of environmental scientists and engineers, led by ... a three-year, $5.25 million grant from the U.S. ... Research to make a direct positive impact on ... and disposal of radioactive contaminants. , "Understanding the ... dealing with environmental aspects of nuclear technologies is ...
(Date:9/30/2014)... can live in almost any aquatic environment on Earth, ... many species are pushed to the limit. The amount ... prove critical for how different species cope in the ... University of Gothenburg, published in the scientific journal ... change continues apace thanks to increasing levels of greenhouse ...
Breaking Biology News(10 mins):Laser-guided sea monkeys show how zooplankton migrations may affect global ocean currents 2Researchers get $5.25 million to advance nuclear technologies in South Carolina 2Shape up quickly -- applies to fish, too! 2
... the Bellvitge Biomedical Research Institute (IDIBELL) at the ... into how the IDPN nitrile causes neurological syndromes ... (ALS), a severe neuromuscular degenerative disease. The study, ... in Neuropathology and Applied Neurobiology journal. ...
... to dust off the garden tables and chairs. But garden furniture ... covered with a slimy film of algae, moss, bacteria and fungi ... hoping that they can solve this problem by incorporating titanium dioxide ... adding a little bit of sunlight. When these titanium dioxide molecules ...
... German . Zebrafish share most organ systems ... the causes of human diseases like cancer or heart diseases. ... With the European Zebrafish Resource Center (EZRC), Karlsruhe Institute of ... such lines in Europe. The EZRC is funded jointly by ...
Cached Biology News:Poisoning from industrial compounds can cause similar effects to ALS 2Cleaning with sunlight 2Zebrafish -- the stars of biomedicine 2
(Date:10/2/2014)... 02, 2014 IAL is pleased ... of its report on the markets for rigid ... examines the developments encountered in the global market ... , Full Report With TOC @ ... trends driving the demand. The study presents production ...
(Date:10/2/2014)... MO (PRWEB) October 02, 2014 Permian ... business in the St. Louis, Missouri, area on October ... has become a leading plastic injection molder in the ... machines and is a supplier to many Fortune 500 ... customer support every step of the way, from concept ...
(Date:10/2/2014)... de 2014 Laborie Medical Technologies, Inc. ("LABORIE"), ... ha completado la adquisición de Unisensor AG y Unisensor ... sede central sita en Wiesendangen, Suiza, y lleva a ... New Hampshire . Unisensor está especializada en el ... para evaluar la presión y valores de pH para ...
(Date:10/2/2014)... -- SIRO Clinpharm, an award-winning Clinical Research ... Annual Conference of the Society for Clinical Data Management ... where they were invited to speak at three sessions. ... to support fraud detection, ,clinical data management,s role in ... together as virtual and integrated teams,. The award-winning streak ...
Breaking Biology Technology:Global Overview of the Spray Polyurethane Foam (SPF) & One Component Foam (OCF) : Industry Analysis, Size, Share, Trends And Forecast Research Report by Researchmoz 2Permian Plastics LLC Celebrates 20 Years As Leading Manufacturer of Plastic Molds 2LABORIE adquiere Unisensor AG y Unisensor USA, Inc. 2SIRO Clinpharm Showcases Biometrics Capabilities at the SCDM 2014 Annual Conference in Las Vegas 2
... 15 MannKind,Corporation (Nasdaq: MNKD ), focused on ... today that it,will present at the UBS Global Life ... (ET) at the Grand Hyatt in New York., ... web cast of the,presentation in the Investor Relations section ...
... Join as Company Enters Commercialization Phase, NAPLES, ... TO ETHANOL(TM), the most advanced third generation biofuels,technology, ... with the,appointments Greg Schlicht as Senior Vice President ... as Senior Program Manager., Mr. Schlicht will ...
... Sept. 15 Insmed Inc. (Nasdaq:,INSM) a developer ... Allan, Ph.D., CEO of Insmed, will present at ... will be discussing,the Company,s perspective on the potential ... will also Chair a panel on this topic ...
Cached Biology Technology:Algenol Biofuels Further Strengthens Team With Key Appointments 2Insmed to Present at Biosimilars 2008 Conference 2