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Team IDs weakness in anthrax bacteria
Date:1/24/2008

en survive the infection.

With the aid of an intracellular probe developed in our laboratory, which fluoresces in the presence of NO, our collaborators Evgeny Nudler and his group discovered a completely new target for the next generation of antibiotics, said Lippard.

With this knowledge in hand, the researchers are now using the fluorescent probe to screen libraries of chemicals for compounds that could potentially interfere with the bacterium's ability to synthesize NO, said Lippard. Such compounds could eventually be developed into new antibiotics.


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Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
Source:Eurekalert

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