Navigation Links
Tapping the body's own defenses, researchers look to cutting-edge gene therapy for bladder cancer
Date:1/10/2012

followed by transfection with B7.1 gene. The addition of the B7.1 gene, which encodes an immune co-stimulatory molecule, enhanced T-cell production logarithmically and produced a 70 percent cure rate. Rechallenge with new cancer cells was also prevented. Clinical translation of this research has been submitted for Institutional Review Board approval at UH Case Medical Center.

Other research by Dr. Larchian and his colleagues aims to leverage this work to develop a gene-therapy system that can be utilized to deliver other key defense genes.

"Our future pursuits," he said, "will include using this system with very specific biological response modifiers, including anti-angiogenesis factors, and with the tumor suppressor gene, MCP3." Dr. Larchian also is developing a targeted drug delivery system using nanoparticles for bladder cancer treatment.


'/>"/>

Contact: George Stamatis
george.stamatis@uhhospitals.org
216-844-3667
University Hospitals Case Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tapping into plants is the key to combat climate change, says scientist
2. Researchers discover novel anti-viral immune pathway in the mosquito
3. MU researchers find unique protein organization in arteries associated with cardiovascular disease
4. Frogs use calls to find mates with matching chromosomes, University of Missouri researchers find
5. Viagra against heart failure: Researchers at the RUB and from Rochester throw light on the mechanism
6. DOE researchers achieve important genetic breakthroughs to help develop cheaper biofuels
7. Drugs used to overcome cancer may also combat antibiotic resistance: McMaster researchers
8. Researchers develop new method of cleaning toxins from the oilsands
9. Researchers discover a way to significantly reduce the production costs of fuel cells
10. San Diego Zoo researchers contribute to project using mummy DNA to differentiate croc species
11. Researchers create living neon signs composed of millions of glowing bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... ALLEN, Va. , May 28, 2015 /PRNewswire/ ... the release of a new report titled "Markets ... materials (reversible polymers, inorganic capsule and vascular systems, ... coatings) will grow to around $2.7 billion by ... deliverable from n-tech,s extensive coverage of smart materials. Other ...
(Date:5/22/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company") ... promotional pricing and making the Wocket generally available for $229 ... Head of Marketing said, "We,ve extended the opportunity to take ... May. To get your wocket at this special price, submit ... on June 1, you,ll receive a unique code that gives ...
(Date:5/20/2015)... May 20, 2015 ... has announced the addition of the  ... Iris Recognition Market"  report to their ... research service analyses trends in the ... and commercial sectors, globally. Despite hardware ...
Breaking Biology News(10 mins):The Market for Self-Healing Materials to Reach $2.7 Billion by 2020 Says New n-tech Research Study 2The Market for Self-Healing Materials to Reach $2.7 Billion by 2020 Says New n-tech Research Study 3NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 3Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2
... contains stem cells with a surprising capacity for repair, ... journal Cell, published by Cell Press. The novel insight ... have clinical implications for the treatment of brain damage, ... mice whose brains were severely damaged by loss of ...
... they have been exposed to biological or chemical weapons could ... who are helping to develop a tiny diagnostic device that ... of a tiny pump, researchers affiliated with MIT's Institute for ... existing miniature "lab on a chip" fully portable, so the ...
... heat-loving archaeon capable of fixing nitrogen at a surprisingly ... Earth’s earliest lineages of organisms capable of nitrogen fixation, ... and animals rely on to fix nitrogen. , ... of Science supports the notion that the gene needed ...
Cached Biology News:Neural stem cells lend the brain a surprising capacity for self-repair 2MIT designs portable 'lab on a chip' 2MIT designs portable 'lab on a chip' 3Microbe fixes nitrogen at a blistering 92 C 2Microbe fixes nitrogen at a blistering 92 C 3
(Date:5/29/2015)... 29, 2015 When a leading ... a request to design an industrial oven ... prescription medications being produced using a 3D-printing process, ... a robotic gantry, heat-saving windows, and internal actuators ... of 3D-printed pills to exact specifications. , To ...
(Date:5/29/2015)... SILVER SPRING, Md. and RESEARCH TRIANGLE ... Therapeutics Corporation (NASDAQ: UTHR ) announced today that ... United Therapeutics, will provide an overview and update on the ... New York City . The ... on Thursday, June 4, 2015, at 11:00 AM Eastern Time, ...
(Date:5/28/2015)... 2015 Research and ... of Jain PharmaBiotech,s new report  "Alzheimer Disease ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... in management. With nearly 8 million sufferers ... markets of the world and anticipated increases ...
(Date:5/28/2015)... , May 27, 2015 Research ... addition of Jain PharmaBiotech,s new report ... their offering. An increasing use ... industries is anticipated. Nanotechnology will be applied ... from formulations for optimal delivery to diagnostic ...
Breaking Biology Technology:New industrial oven with “pill pushing” robotic gantry precisely removes excess moisture from 3D-printed pharmaceuticals 2Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 2Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 3Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 3
... may not rank with the Dating Game , Love ... Madison-based online service is doing a little matchmaking of its own. ... companies with board candidates, has thus far focused on Dane County ... lane on the information super highway. , ,The service has received ...
... Wis. - Commercial air service doesn't always ... viewed as more fundamental to enterprise than ever ... potential customers to dismiss the expenses of putting ... of Internet video and mixed-media communication tools. , ...
... an effective board of directors, it's a different world than the ... accounting scandals that rocked corporate America and led to the passage ... commitment than ever, and there is more liability and more risk ... public or private - ensure that its board not only has ...
Cached Biology Technology:Online service makes board connections 2Online service makes board connections 3IP video goes where air travel cannot 2IP video goes where air travel cannot 3Directors more assertive in corporate governance 2Directors more assertive in corporate governance 3Directors more assertive in corporate governance 4
... ZMD.440. Immunogen: Synthetic peptide derived from ... (platelet derived growth factor D iris-expressed growth ... differs from mouse and rat by one ... the ~50 kDa human mouse and rat ...
...
...
...
Biology Products: