Navigation Links
Tapping the body's own defenses, researchers look to cutting-edge gene therapy for bladder cancer
Date:1/10/2012

followed by transfection with B7.1 gene. The addition of the B7.1 gene, which encodes an immune co-stimulatory molecule, enhanced T-cell production logarithmically and produced a 70 percent cure rate. Rechallenge with new cancer cells was also prevented. Clinical translation of this research has been submitted for Institutional Review Board approval at UH Case Medical Center.

Other research by Dr. Larchian and his colleagues aims to leverage this work to develop a gene-therapy system that can be utilized to deliver other key defense genes.

"Our future pursuits," he said, "will include using this system with very specific biological response modifiers, including anti-angiogenesis factors, and with the tumor suppressor gene, MCP3." Dr. Larchian also is developing a targeted drug delivery system using nanoparticles for bladder cancer treatment.


'/>"/>

Contact: George Stamatis
george.stamatis@uhhospitals.org
216-844-3667
University Hospitals Case Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tapping into plants is the key to combat climate change, says scientist
2. Researchers discover novel anti-viral immune pathway in the mosquito
3. MU researchers find unique protein organization in arteries associated with cardiovascular disease
4. Frogs use calls to find mates with matching chromosomes, University of Missouri researchers find
5. Viagra against heart failure: Researchers at the RUB and from Rochester throw light on the mechanism
6. DOE researchers achieve important genetic breakthroughs to help develop cheaper biofuels
7. Drugs used to overcome cancer may also combat antibiotic resistance: McMaster researchers
8. Researchers develop new method of cleaning toxins from the oilsands
9. Researchers discover a way to significantly reduce the production costs of fuel cells
10. San Diego Zoo researchers contribute to project using mummy DNA to differentiate croc species
11. Researchers create living neon signs composed of millions of glowing bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... . Why do ... to reproduce? And why are there two sexes anyway? These ... of the research journal Molecular Human Reproduction published ... Bielefeld University Bielefeld has compiled this special issue on sperm ... to copulate with several males in quick succession – chimpanzees ...
(Date:10/16/2014)... and Washington land managers have a new synthesis of ... moist mixed-conifer (MMC) forests in the two states. ... in Eastern Oregon and Washington: A Synthesis of the ... a general technical report published by the U.S. Forest ... to a request from managers for a synthesis of ...
(Date:10/16/2014)... 2014 NXT-ID, Inc. (NASDAQ: NXTD ... authentication company focused on the growing mobile commerce market ... Wocket™, the Smart Wallet, at the 13 th ... leading global conference on the intersection of technology and ... Anderson , founder and publisher of the Strategic News ...
Breaking Biology News(10 mins):Sperm wars 2New report synthesizes best available science on management of moist mixed-conifer forests 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3
... Smart Search & Match,the leading provider of high-performance ... has joined the company as Product Marketing Manager. ... 15 years of product and marketing management,experience to ... many high-tech products and solutions worldwide. He has ...
... 2008 An international research team led by Tim ... the director of the School of Medicine,s Center for ... alternative splicing, the process by which single genes produce ... that curing the more than half of genetic diseases ...
... what they think may be a basic recipe for ... stem cells from essentially any mammal, including cows, pigs ... December 26th issue of the journal Cell , ... demonstrated to work in mice earlier this year, which ...
Cached Biology News:Case Western Reserve finds mechanism underlying alt. splicing of premessenger RNA into messenger RNA 2Case Western Reserve finds mechanism underlying alt. splicing of premessenger RNA into messenger RNA 3Recipe for capturing authentic embryonic stem cells may apply to any mammal, study suggests 2Recipe for capturing authentic embryonic stem cells may apply to any mammal, study suggests 3
(Date:10/17/2014)... PA (PRWEB) October 17, 2014 ... being called upon by health facilities around the ... patients are being treated. Among the many places ... includes Texas Health Presbyterian Hospital Dallas and at ... The state-of-the-art vapor-producing robots have been utilized to ...
(Date:10/17/2014)... The global SWIR market report defines and ... of revenue. This market is valued at $60.1 million ... by 2019, at a CAGR of 10.2% from 2014 ... global SWIR market report, to get an idea of ... of the segmentation of the market, and is supported ...
(Date:10/17/2014)... The North American Knowledge-based/Evidence-based Clinical ... segments the market in North America with analysis ... in North America is expected to reach around ... of 8.1% from 2013 to 2018. , Browse ... clinical decision support system (CDSS) market, to get ...
(Date:10/17/2014)... The Middle East and Africa Location Based Services (LBS) ... Middle East and Africa with analysis and forecast of revenue. ... 2014 to $3,403.1 million by 2019, at a CAGR of ... of the Middle East and Africa Location Based Services (LBS) ... provided. It also provides a glimpse of the market segmentation, ...
Breaking Biology Technology:Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 2Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 3Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 4Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 5Bioquell’s Vapor Producing Robots Selected to Combat Ebola in Hospitals Around the World 6The global SWIR market is expected to reach $97.9 million by 2019 - New Report by MicroMarket Monitor 2The global SWIR market is expected to reach $97.9 million by 2019 - New Report by MicroMarket Monitor 3The North American Knowledge-based/Evidence-based Clinical Decision Support System (CDSS) market is expected to reach around $283.3 million by 2018 - MicroMarket Monitor 2The North American Knowledge-based/Evidence-based Clinical Decision Support System (CDSS) market is expected to reach around $283.3 million by 2018 - MicroMarket Monitor 3The North American Knowledge-based/Evidence-based Clinical Decision Support System (CDSS) market is expected to reach around $283.3 million by 2018 - MicroMarket Monitor 4The North American Knowledge-based/Evidence-based Clinical Decision Support System (CDSS) market is expected to reach around $283.3 million by 2018 - MicroMarket Monitor 5The Middle East and Africa Location Based Services (LBS) market is estimated to reach $3,403.1 million by 2019 - New Report by MicroMarket Monitor 2The Middle East and Africa Location Based Services (LBS) market is estimated to reach $3,403.1 million by 2019 - New Report by MicroMarket Monitor 3The Middle East and Africa Location Based Services (LBS) market is estimated to reach $3,403.1 million by 2019 - New Report by MicroMarket Monitor 4
... Davis, PhD, Aiguo Zhang, PhD, Chloe Etienne, Ivan Huang,and Michele Malit, Bio-Rad Laboratories, Inc., ... , Introduction , ... immunoassays. , The concentrations of analytes in ... using a calibration or standard curve. More specifically, , ...
... Gao, Kris Simonyi, and Claudia Suen, Bio-Rad Laboratories, Inc.,2000 Alfred Nobel Drive, Hercules, CA ... Introduction , ... proteins within a variety of cell culture and tissue ... techniques that apply a sandwich antibody capture approach , ...
... RNA Isolation Kit , Catalog #732-6370 , ... Method , Cell Lysis ... tissue to a , tissue grinder tube on ice and then ... in liquid nitrogen with a porcelain mortar and pestle. , Keep ...
Cached Biology Technology:Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 2Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 3Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 4Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 5Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 6Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 7Principles of Curve Fitting for Multiplex Sandwich Immunoassays, Rev B 8Detection of Phosphorylated and Total ERK and p38 MAPK by Bio-Plex Assay, ELISA, and Western Blotting, Rev A 2Detection of Phosphorylated and Total ERK and p38 MAPK by Bio-Plex Assay, ELISA, and Western Blotting, Rev A 3Detection of Phosphorylated and Total ERK and p38 MAPK by Bio-Plex Assay, ELISA, and Western Blotting, Rev A 4Detection of Phosphorylated and Total ERK and p38 MAPK by Bio-Plex Assay, ELISA, and Western Blotting, Rev A 5Total RNA Isolation From 50100 mg Plant Tissue 2
... is designed for easy transformation of the ... for successful transformation simply by mixing a ... cultured yeast cells. No complicated steps, such ... The kit is particularly well suited for ...
... lab productivity and allows you to achieve a ... ahead beyond traditional paper-based weighing processes into a ... supported: Control ... XP, PR, SR, PG-S, PG, SG, AT, MT, ...
XPLAC (S-17)...
High affinity antibody reacting with S-100 ab heterodimer. Could be used for Western blotting application and immunoassay....
Biology Products: