Navigation Links
Taking the fight against cancer to heart
Date:2/26/2008

BETHESDA, Md. (Feb. 25, 2008) Hormones produced by the heart eliminated human pancreatic cancer in more than three-quarters of the mice treated with the hormones and eliminated human breast cancer in two-thirds of the mice, according to researcher David Vesely, a doctor at the James A. Haley Veterans Hospital in Tampa and a professor at the University of South Florida (USF).

The treatment has not yet been tried in humans, but a private biotechnology company is raising money in the hope of beginning human trials. Vesely is the hospitals chief of endocrinology, diabetes and metabolism and is also professor of medicine, molecular pharmacology and physiology at USF.

He will present his research at a symposium April 9 at the Experimental Biology 2008 conference in San Diego. The American Federation for Medical Research sponsors the session, which takes place during the annual meeting of The American Physiological Society.

The discovery of cardiac hormones

For more than 350 years, scientists and physicians thought the heart was a pump, delivering blood and oxygen to the body. But that view changed dramatically in 1981 when Adolfo deBold discovered that the heart produces atrial natriuretic factor (ANF), so-named because it is produced in the atrium of the heart and stimulates the production of urine and the excretion of sodium.

Vesely later discovered three more hormones that are produced from the same gene as ANF. He called them:

  • Long acting natriuretic peptide, which also stimulates urine production and sodium excretion.

  • Vessel dilator which opens the blood vessels and lowers blood pressure

  • Kaliuretic peptide which increases potassium excretion

The hormones, called peptide hormones because they are composed of amino acids, help regulate blood volume and blood pressure. Most hormones, including such well-known hormones as insulin, are peptide h
'/>"/>

Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Aging gracefully requires taking out the trash
2. Clemson chemists discover new way antioxidants fight debilitating diseases
3. Social habits of cells may hold key to fighting diseases
4. Advance in effort to fight malaria by tricking the mosquitos sense of smell
5. Yale scientists use nanotechnology to fight E. coli
6. Researchers develop liquid crystal pharmaceuticals to fight cancer and other diseases
7. Japanese beetle may help fight hemlock-killing insect
8. When it comes fighting to C. difficile, the Palme dOr goes to soap and warm water
9. Fighting the spread of food poisoning
10. Gold nanorods shed light on new approach to fighting cancer
11. UMass Medical School researchers receive $8.5M grant award to fight AIDS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2015)... , July 27, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced that Huawei has selected ... solution for its stylish smartwatch. Huawei chose the ... reliability, low power and highly responsive human interface ... Huawei designers also required a classic round watch ...
(Date:7/21/2015)... July 21, 2015 Today, ZTE announced its ... as well as expected revenues in 2015 that relate to sales ... revenue guidance of approximately 2,200 MSEK for 2015. Jörgen ... leading smartphone manufacturer in China and we ... 02 5 for Axon , ...
(Date:7/13/2015)... , July 13, 2015 Synaptics Inc. ... human interface solutions, today announced sampling of ClearPad ... display driver integration (TDDI) product targeting smartphones and ... to combine Synaptics , best-in-class touch controller ... driver technology developed in the company,s Japan Design ...
Breaking Biology News(10 mins):Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3FPC's Touch Fingerprint Sensor FPC1025 in ZTE's Smartphone Axon 2Synaptics Announces Sampling of Second Generation TDDI Solutions 2Synaptics Announces Sampling of Second Generation TDDI Solutions 3
... If you carried a gene that increased your risk ... know? Do perceptions of stigma and discrimination against people ... disease? Sara Shostak, assistant professor in the department ... of epidemiology at Columbia University, and other collaborators were ...
... - Mercyhurst University biologists have received a $30,000 grant to ... woolly adelgid, a small, aphidlike insect that is decimating the ... considered one of the greatest threats to our eastern forests; ... Georgia," said Michael Elnitsky, assistant professor of biology, who wrote ...
... Institute at Oregon State University have discovered yet another reason ... is so good for you it provides not just ... mechanism of epigenetics. Epigenetics, an increasing focus of research ... but also to the way that diet, toxins and other ...
Cached Biology News:Grant to fund research into psychosocial impacts of epilepsy testing 2Grant to fund research into psychosocial impacts of epilepsy testing 3Mercyhurst research aims to predict impact of invasive forest pest 2Another mechanism discovered by which sulforaphane prevents cancer 2
(Date:7/29/2015)... BIRMINGHAM, Ala., July 29, 2015 /PRNewswire/ ... the nation,s largest providers of post-acute healthcare services, ... reported its results of operations for the second ... second quarter was characterized by strong volume growth ... our Adjusted EBITDA," said Jay Grinney, President and ...
(Date:7/29/2015)... MILWAUKEE, Wis. (PRWEB) , ... July 29, 2015 ... ... facility identification solutions, today announced its GHS Label Guide . To align ... Harmonized System (GHS), this guide includes explanations of label components, an example of ...
(Date:7/29/2015)... , July 29, 2015  Indivior PLC (LON: INDV) ... naloxone nasal spray was accepted and received Priority Review ... the treatment of opioid overdose. This naloxone nasal spray ... formulated for optimal absorption into the nasal mucosa. 1 ... training so individuals may be better equipped to help ...
(Date:7/29/2015)... Francisco, CA (PRWEB) , ... July 29, 2015 , ... ... in the morning is quite normal. Although there are a considerable number of terms ... well understood that this post-sleep material is a mixture of mucus, blood cells, skin ...
Breaking Biology Technology:HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27HealthSouth Reports Results for Second Quarter 2015 28HealthSouth Reports Results for Second Quarter 2015 29HealthSouth Reports Results for Second Quarter 2015 30HealthSouth Reports Results for Second Quarter 2015 31HealthSouth Reports Results for Second Quarter 2015 32HealthSouth Reports Results for Second Quarter 2015 33HealthSouth Reports Results for Second Quarter 2015 34HealthSouth Reports Results for Second Quarter 2015 35HealthSouth Reports Results for Second Quarter 2015 36
... , WALTHAM, Mass., Oct. 20 Inverness Medical Innovations, Inc. ... to take charge of their health at home through the ... it will release its third quarter 2009 earnings on Tuesday, ... call beginning at 10:00 a.m. (Eastern Time) on that date ...
... Transdel Pharmaceuticals, Inc. (OTC Bulletin Board: TDLP), a specialty ... its proprietary transdermal delivery platform, today announced that Dr. ... will present a company overview at two upcoming ... annual BIOCOM Investor Conference in San Diego, CA on ...
... 20 GeoVax Labs, Inc. (OTC Bulletin ... Atlanta-based, biopharmaceutical company developing human vaccines for diseases caused ... today announced that it will move its corporate headquarters ... University to Smyrna, Georgia, a northwest suburb of Atlanta, ...
Cached Biology Technology:Inverness Medical Innovations Schedules Conference Call for 10:00 a.m. ET October 27, 2009 to Discuss Third Quarter 2009 Results 2Transdel Pharmaceuticals to Present at Two Investor Conferences 2Transdel Pharmaceuticals to Present at Two Investor Conferences 3GeoVax Labs, Inc. Moving Operations to Smyrna, Georgia 2GeoVax Labs, Inc. Moving Operations to Smyrna, Georgia 3GeoVax Labs, Inc. Moving Operations to Smyrna, Georgia 4