Navigation Links
Taking the 3-D measure of macromolecules:
Date:6/16/2011

.

"Two noble metallic nanoparticles in close proximity will couple with each other through their plasmon resonances to generate a light-scattering spectrum that depends strongly on the distance between the two nanoparticles," Alivisatos says. "This light-scattering effect has been used to create linear plasmon rulers that have been used to measure nanoscale distances in biological cells."

Compared to other types of molecular rulers, which are based on chemical dyes and fluorescence resonance energy transfer (FRET), plasmon rulers neither blink nor photobleach, and also offer exceptional photostability and brightness. However, until now plasmon rulers could only be used to measure distances along one dimension, a limitation that hampers any comprehensive understanding of all the biological and other soft-matter processes that take place in 3D.

"Plasmonic coupling in multiple nanoparticles placed in proximity to each other leads to light scattering spectra that are sensitive to a complete set of 3D motions," says Laura Na Liu, corresponding author of the Science paper. "The key to our success is that we were able to create sharp spectral features in the otherwise broad resonance profile of plasmon-coupled nanostructures by using interactions between quadrupolar and dipolar modes."

Liu explains that typical dipolar plasmon resonances are broad because of radiative damping. As a result, the simple coupling between multiple particles produces indistinct spectra that are not readily converted into distances. She and her co-authors overcame this problem with a 3D ruler constructed from five gold nanorods of individually controlled length and orientation, in which one nanorod is placed perpendicular between two pairs of parallel rod nanorods to form a structure that resembles the letter H.

"The strong coupling between the single nanorod and the two parallel nanorod pairs suppresses radiative damping and allows for t
'/>"/>

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Arthritis patients taking newer treatments do not have an overall increased cancer risk
2. Major European project taking steps to protect pollinators
3. Prostate cancer spreads to bones by overtaking the home of blood stem cells
4. Why are vines overtaking the American tropics?
5. Land evapotranspiration taking unexpected turn: huge parts of world are drying up
6. WSU researchers taking sustainability of organic farming to new level
7. Taking a new look at old digs: Trampling animals may alter Stone Age sites
8. Taking the pulse of coral reefs
9. Report: Discovery networks hostage-taking a rare terror event
10. Taking the guesswork out of soil classification
11. Tracing natural hazards by taking Earths pulse
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Taking the 3-D measure of macromolecules:
(Date:10/22/2014)... 20, 2014 The Nano-Bio Manufacturing Consortium (NBMC), ... Research Laboratory (AFRL), has chosen a project proposed by ... University of Arizona College of Medicine – ... project,s goal is to assess different sweat collection methods ... of sweat under a variety of human-body conditions, the ...
(Date:10/18/2014)... and stress-related psychiatric disorders are associated with ... molecular mechanisms underlying this relation are unknown. ... development of targeted preventive strategies and new ... This work is presented at the European ... an international group of researchers from Germany ...
(Date:10/17/2014)... . Why do ... to reproduce? And why are there two sexes anyway? These ... of the research journal Molecular Human Reproduction published ... Bielefeld University Bielefeld has compiled this special issue on sperm ... to copulate with several males in quick succession – chimpanzees ...
Breaking Biology News(10 mins):Nano-Bio Manufacturing Consortium Selects Project Proposed by Arizona Center for Integrative Medicine to Optimize Human Performance Monitoring Techniques 2Nano-Bio Manufacturing Consortium Selects Project Proposed by Arizona Center for Integrative Medicine to Optimize Human Performance Monitoring Techniques 3Researchers find why depression and aging linked to increased disease risk 2Sperm wars 2
... "the trots," "Montezuma,s Revenge," "the runs" and worse. But no ... medicine that could go straight to the offending bacteria to ... true if work by Texas A&M University scientists stays on ... A "medicine that grows" is how the phage concept ...
... Unusual features of the human placenta may be ... of maternal deaths during childbirth, according to evolutionary research ... as the loss of more than a pint of ... accounts for nearly 35 percent, or 125,000, of the ...
... on the latest news in science and technology, consider a ... for Nov. 9, 2011. The event, sponsored by the ... and brightest graduate students to display their research on clearly ... Institute of Technology, Rutgers University -- Newark and the University ...
Cached Biology News:Texas A&M center confronts antibiotic crisis with potential new bacterial treatment 2Texas A&M center confronts antibiotic crisis with potential new bacterial treatment 3Texas A&M center confronts antibiotic crisis with potential new bacterial treatment 4Evolution offers clues to leading cause of death during childbirth 2NJIT grad students display work at 7th annual Research Day on Nov. 9 2
(Date:10/20/2014)... October 20, 2014 The report ... Dispensing Systems, Packaging and Labeling Systems, Table-top Counters) ... - Global Forecasts & Trends to 2019” analyzes ... opportunities in North America, Europe, Asia-Pacific, and the ... market tables and 30 figures spread through 300 ...
(Date:10/20/2014)... Calif. , Oct. 20, 2014 ... that the Company has signed a Notice of ... Regenerative Medicine (CIRM), effective October 1, 2014.  The ... Development payments and the release of additional grant ... CIRM grant award for clinical development of Asterias, ...
(Date:10/20/2014)...  GenVec, Inc. (NASDAQ: GNVC ) today announced ... its board of directors effective on October 24, 2014.   Dr. ... as its chairman from June 2006 to November 2013.  During ... Governance and Audit Committees of the board.  ... dedicated service to GenVec, and its stockholders," said Wayne ...
(Date:10/20/2014)... Earle Martin , Chief Executive ... Ellen Teplitzky, an experienced attorney specializing in business ... has joined the firm as Director of Legal ... NDA Partners provides legal services, including research, ... top law firms and their clients in cases ...
Breaking Biology Technology:Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 2Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 4Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 4Zola P. Horovitz To Retire From GenVec Board 2NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
... , , , ... , , , RNA ... tool for target identification and target validation,in therapeutic research. , ... A growing number of different cell lines are used for,gene ...
... , , ... , , , Since the ... of foreign genes,appeared a few years ago, RNAi has become a ... short double-stranded RNAs that are,homologous to the suppressed gene. These small ...
... , , ... , , , , ... detection of beer-spoilage bacteria on the,LightCycler Instrument) in combination with the ... on the MagNA Pure LC Instrument) offers,breweries an innovative and automated ...
Cached Biology Technology:Housekeeping Genes: Universal Positive,Controls in siRNA Knockdown Experiments 2Housekeeping Genes: Universal Positive,Controls in siRNA Knockdown Experiments 3Quantification of siRNA Silencing Efficiency,Using the LightCycler System 2Quantification of siRNA Silencing Efficiency,Using the LightCycler System 3Quantification of siRNA Silencing Efficiency,Using the LightCycler System 4Quantification of siRNA Silencing Efficiency,Using the LightCycler System 5Screening of Beer-Spoilage Bacteria Using,the LightCycler PCR Workflow System 2Screening of Beer-Spoilage Bacteria Using,the LightCycler PCR Workflow System 3Screening of Beer-Spoilage Bacteria Using,the LightCycler PCR Workflow System 4Screening of Beer-Spoilage Bacteria Using,the LightCycler PCR Workflow System 5
... Label IT siRNA Tracker Intracellular Localization ... a straight forward approach to directly ... design, in an efficient yet non-destructive ... Subcellular localization and functional inhibition of ...
... LC/MS, using mass numbers as a trigger, ... for performing investigation and research of natural ... analytical and preparative operation. Switching between modes ... software. This support provides a quick solution ...
... Tracker Intracellular Localization Kit provides a straight ... siRNA, of your design, in an efficient ... experiments. Subcellular localization and functional inhibition of ... introduction of the labeled siRNA into mammalian ...
... Although the Beacon 2000 instrument can ... instrument, the Beacon 2000 Data Manager Software ... data imported directly from the instrument. These ... into commercially available spreadsheets, such as Microsoft ...
Biology Products: