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TYRX AIGISRx antibacterial envelope shows low infection rate, high CIED procedure success
Date:10/19/2010

ere successful CIED implantation and CIED infection. The study enrolled a high proportion of patients with established risk factors for CIED infection: 67.5% underwent revision or replacement procedures, and 36.5% had procedures with a CRT- defibrillator (CRT-D).

Currently, more than 500,000 CIEDs are implanted in the United States each year. CIED infections occur in association with 1-7% of these devices and are associated with significant morbidity, mortality, and expense. The AIGISRx Antibacterial Envelope is designed to reduce infection risk by eluting the antibiotics minocycline and rifampin for 7-10 days after implantation with the CIED. This antibiotic combination has been shown to reduce infections associated with medical devices in multiple randomized controlled trials.

TYRX Chief Medical Officer, Daniel Lerner, M.D. commented, "Previous studies have demonstrated that coating or impregnating medical devices with the antibiotics minocycline and rifampin significantly reduces device-related infections. The COMMAND Study is important because it generated data on the clinical performance of an FDA-cleared device that provides sustained local delivery of these antibiotics in the generator pocket after CIED implantation, in a population at high risk for CIED infection."


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Contact: Joan Kureczka
Joan@kureczka-martin.com
Kureczka/Martin Associates
Source:Eurekalert

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