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TGen researcher awarded American Cancer Society fellowship
Date:5/12/2010

nd three years, and there is an urgent need to improve treatment of AML.

Therapeutic drugs that target single cellular processes have shown limited impact in fighting this type of cancer. Because AML results from a progression of multiple cellular processes, Dr. Bogenberger's project proposes to attack the cancer by identifying targets to inhibit in combination with drugs already approved by the U.S. Food and Drug Administration 5-Azacytidine and suberoylanilide hydroxamic acid (SAHA).

His fellowship project will use cutting-edge methodologies to systematically look for genes that, when silenced, "increase the anti-leukemic potency" of these epigenetic therapies, according to the ACS project summary.

Dr. Bogenberger's ACS award will allow him to build on previous research into AML he has conducted since joining TGen in October 2008.

"Since James joined the lab, he has done excellent work and actively contributed to move projects forward, and we are initiating clinical trials as we speak from results that have come out of these projects," Dr. Tibes said. "This fellowship is well deserved and I congratulate him."


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Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

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