Navigation Links
TGen-led studies identify genetic links to kidney disease, kidney failure
Date:6/26/2010

n an association between PVT1 and kidney failure in patients with diabetes, both autoimmune (type 1) and that most commonly caused by excessive weight, poor diet and lack of exercise (type 2).

In the new study, researchers found that PVT1 was expressed in mesangial cells, which are specialized cells around blood vessels in the kidneys, at a rate up to five times higher in conditions of high glucose (high blood sugar), compared to normal glucose levels. High blood sugar is a signature symptom of diabetes.

"These findings show that additional study of the role of PVT1 in diabetic kidney disease is well-justified," said Dr. Lucrecia Alvarez, a TGen Post-Doctoral Fellow and the first author of the study's abstract. Dr. Alvarez announced the findings during an oral presentation at the ADA sessions.


'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. International TGen-led team finds link between brain protein and Alzheimers disease
2. Claims of sex-related differences in genetic association studies often not properly validated
3. Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring
4. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
5. Studies: Children obese due to a host of unhealthy pressures
6. Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients
7. LSU professor studies army-ant-following birds
8. 2 carotid artery stenting studies show results comparable to AHA guidelines
9. NIH grants enable energy studies
10. New studies on schizophrenia, depression, trauma and autism highlight annual meeting
11. Experts from Stevens, Merck, publish joint paper, Biosynthetic Studies of Platensimycin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... the "iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... Apple introduced the fingerprint reading feature with the iPhone ...
(Date:12/19/2014)... 2014   LaunchKey , the first decentralized mobile authentication ... of Things era, today announced the close of $3 ... led by Metamorphic Ventures with participation from ENIAC Ventures, ... others.  LaunchKey has raised $4 million to date, and ...
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB SM ... (GCP) audit to confirm its adherence to current U.S. ... HITLAB to conduct regulated smart device and smart phone ... and research quality. "HITLAB is determined to ...
Breaking Biology News(10 mins):iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... available in German . , Helmholtz Zentrum ... European Union, has been expanded to include six partners from ... partners will join the effort of the other 22 members ... improve open access to high-quality mouse models. Animal models have ...
... Energy (DOE) Joint Genome Institute (JGI) now has a ... 13th Annual Applied Ergonomics Conference held March 22-25, 2010 ... highlights ergonomic innovations from institutions and multinational corporations. The ... for the Ergonomic Program Improvement Initiatives category. Ergonomics ...
... preliminary study by New Zealand company Plant & Food ... breathing in some types of asthma. Researchers found ... lung inflammation with a multi-action assault in allergy-induced asthma. ... the natural defence mechanisms in lung tissue by both ...
Cached Biology News:Biomedical research infrastructure goes global: EU consortium Infrafrontier has new partners 2Breathe easy: A natural fruit compound may help asthma 2
(Date:1/23/2015)... BioPharma Inc. (NASDAQ: ARRY ) today announced ... Pharma AG to acquire worldwide rights to encorafenib (LGX818), ... agreement is conditional on the closing of transactions announced by ... are expected to close in the first half of ...
(Date:1/22/2015)... 22, 2015 Shimadzu Scientific Instruments ... multipurpose UV-visible spectrophotometer. Offering wavelength scanning from 190 ... ideal for applications in a variety of industries, ... The user-friendly UV-1280 enables intuitive operation, while the ...
(Date:1/22/2015)... , Jan. 22, 2015  Transwestern | RBJ today announces the ... office space for Shire a leading biopharmaceutical company, at Two ... | RBJ,s Robert Richards , president, and Brian ... for the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... Protocol Networks brings independent technology consulting ... brand-neutral, independent consultants, Protocol Networks has recently announced its ... the years, his company has attracted several clients in ... as well as others. With the success of these ...
Breaking Biology Technology:Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 2Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 3Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 4Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 5Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 6Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 7Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
... , , , , , , ... To extract RNA from washed and pelleted cultured cells, add 200 , ... Isothiocyanate, 25 mM Sodium Citrate, pH 7.0, 1 M b-Mercaptoethanol) , ... 6 cells. , To directly extract RNA from cultured ...
... , , , Note: Genomic DNA is fragile. High molecular ... large-bore pipet tips or equipment when , pipetting genomic DNA. Do ... Place a 1 cm tail sample into a 1.5 ml ... at 20C. To minimize possible cross-contamination, , ...
... , , , , , , ... the , isolation of total RNA from cell and ... method, because the entire aqueous phase can be recovered , ... involved in RNA isolation with TRIzol Reagent and Phase Lock Gel-Heavy. ...
Cached Biology Technology:Total RNA Isolation Protocol 1,2,3 2Total RNA Isolation Protocol 1,2,3 3Mouse Tail Genomic DNA Isolation Protocol(1) 2Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock , Gel-Heavy 2Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock , Gel-Heavy 3
... organic acid analysis standard is ... organic salts; molecular weights range ... standard is provided for use ... and the organic acid analysis ...
Compound(s) tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential CV/Renal liabilities of compounds....
Compound(s) tested through a broad panel of 38 ligand binding and enzyme assays targeting the Central Nervous System. Used to determine selectivity and potential GI liabilities of compounds....
... The ProteoSpin Detergent Clean-up Micro Kit provides ... removal of SDS, Triton X-100 and other detergents ... spin-column chromatography using Norgens patented protein resin as ... processing 2 50 g of either acidic or ...
Biology Products: