Navigation Links
TGen-Scottsdale Healthcare researchers make breakthrough in lung cancer
Date:1/13/2010

SCOTTSDALE, Ariz. Jan. 13, 2010 Researchers for TGen Clinical Research Services at Scottsdale Healthcare (TCRS) have identified a way to predict which patients with small-cell lung cancer may be resistant to first-line chemotherapy.

The study, Tumor MicroRNA Biomarkers Associated with De Novo Chemoresistance in Small Cell Lung Cancer, will be presented today in San Diego at a joint conference of the American Association for Cancer Research (AACR) and the International Association for the Study of Lung Cancer (IASLC).

This breakthrough is critical since patients with small-cell lung cancer (SCLC) often do not get a second chance at therapies to combat this aggressive type of cancer.

"For patients with small cell lung cancer, there are really only about two chemotherapy options. We need to be more precise with our treatments and identify who is going to be resistant up front in order to design better clinical trials that will identify effective therapies for these at-risk patients," said Dr. Glen J. Weiss, director of Thoracic Oncology at TCRS, who presented the findings at AACR-IASLC's Joint Conference on Molecular Origins of Lung Cancer.

TCRS is a partnership between the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare that enables laboratory discoveries to be quickly turned into targeted therapies that can be tested with patients at the Virginia G. Piper Cancer Center in Scottsdale.

Of the nearly 32,000 new cases of SCLC diagnosed in the U.S. every year, between 15 and 30 percent will be chemoresistant to first-line therapy, or about 6,500 SCLC patients annually. SCLC tends to spread much more quickly than non-small cell lung cancer. There are three types of SCLC: small cell carcinoma (oat cell cancer), mixed small cell/large cell carcinoma, and combined small cell carcinoma.

The study led by Dr. Weiss proposed to look at how to best identify those SCLC patients who would be che
'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. GE Healthcare to evaluate and develop novel imaging technology
2. Scott & White Healthcare researcher finds success with new anti-cancer drug
3. Scott & White Healthcare researcher finds success with new anti-cancer drug
4. GE Healthcare President & CEO, Mark Vachon, to Present at BioConference Live
5. TGen Clinical Research Services at Scottsdale Healthcare and Mayo Clinic study new cancer drug
6. Phoenix conference highlights TGens and Scottsdale Healthcares contributions to molecular oncology
7. TGen, Scottsdale Healthcare, Mayo Clinic study new drug to stimulate immune system of cancer victims
8. Sangamo BioSciences to Present at the Bank of America 2008 Healthcare Conference
9. Hand hygiene initiative aims to decrease healthcare-associated infection in developing countries
10. Conference to examine role technology can play in helping US manage healthcare costs
11. Researchers discover genetic differences between lethal and treatable forms of leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... Conn. , July 7, 2015 NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market announces a revised version ... this week. The commercial will air on CNBC in ... Los Angeles and San Francisco ... The commercial focuses on Wocket,s ability to replace all the cards ...
(Date:7/2/2015)... 2, 2015 Fingerprint Cards has received ... and FPC1155 from the distributor World Peace Industrial Group (WPI), ... in Asia . Deliveries are planned to ... be used by smartphone manufacturers in Asia ... the communicated revenue guidance of approximately 2,200 MSEK for 2015. ...
(Date:6/29/2015)... , June 24, 2015 ... addition of the "Latin America Biomedical Sensors Market ... their offering. The Latin America Biomedical Sensors ... a CAGR of 2.04% over the period 2014-2020 ... are adaptable to the genetic formulation of each individual. ...
Breaking Biology News(10 mins):Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2Latin America Biomedical Sensors Market Report 2015-2020 2
... passage of the Endangered Species Act in 1973, over 1,300 ... its territories. In the forthcoming issue of Ecology Letters, Male ... status trends and show that the length of time species ... conservation are key variables in explaining trends. , Overall, about ...
... analyze DNA from giant, extinct lemurs, according to a Yale ... the National Academy of Sciences. , Radiocarbon dating of the ... that each of the individuals analyzed died well over 1,000 ... professor in the Department of Ecology and Evolutionary Biology. , ...
... Novel use of genetic testing methods helped public health ... outbreaks of foodborne hepatitis A virus in 2003 related ... detailed analysis published in the October 15 issue of ... The authors of the study, Joseph J. Amon, PhD, ...
Cached Biology News:Ancient DNA confirms single origin of Malagasy primates 2Disrupting Cocaine-memories To Battle Addiction 2
(Date:7/7/2015)... -- SME,s Advanced Manufacturing Media is proud to announce the ... young men and women who have demonstrated leadership and ... Manufacturing Engineering magazine highlights these ... Among the standouts: Christopher Tyler , 28, who ... topology of flapping wing vehicles; Kathryn Tillery-Merk , ...
(Date:7/7/2015)... ... July 07, 2015 , ... ... community in the biometrical area. What began as a conference for European Statistical ... for various functions in the biometrical area. Statistical Programmers, Data Managers and Biostatisticians ...
(Date:7/6/2015)... ... July 06, 2015 , ... An optical ... reveal how blood flows in the brain during stroke, providing information that could ... new article published in the journal Neurophotonics describes work at the ...
(Date:7/6/2015)... NASHVILLE, Tenn. , July 6, 2015 ... has entered into a definitive agreement to ... technology and intervention platforms that combine data ... and reporting capabilities to achieve actionable insights ... acquisition will combine Altegra Health,s risk adjustment ...
Breaking Biology Technology:SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 2SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 3SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 4SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 5PhUSE Delighted to Welcome Member Number 5.000 2Reducing Stroke Damage May be Next Application for OCT Technology Now Widely Used in Eye and Vision Healthcare 2Reducing Stroke Damage May be Next Application for OCT Technology Now Widely Used in Eye and Vision Healthcare 3Emdeon to Acquire Altegra Health 2Emdeon to Acquire Altegra Health 3Emdeon to Acquire Altegra Health 4
... SOUTH SAN FRANCISCO, Calif., Jan. 12 Sunesis Pharmaceuticals, ... clinical update on voreloxin, its novel investigational drug candidate ... myeloid leukemia (AML) and ovarian cancer. The clinical ... Annual JP Morgan Healthcare Conference in San Francisco. "2008 ...
... Calif., Jan. 12 MAP,Pharmaceuticals, Inc. (Nasdaq: ... 3 clinical programs, Unit Dose Budesonide (UDB) for children,with ... For UDB, all,patients have completed the 12 week ... for MAP0004, the company currently expects to complete,enrollment in ...
... Calif., Jan. 12 Anacor Pharmaceuticals today,announced that it ... million from its collaboration partner, GlaxoSmithKline. Anacor may,receive ... to clinical development and commercial sales. , ... we have made as a result of,the alliance we ...
Cached Biology Technology:Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin 2Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin 3Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin 4Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin 5Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin 6MAP Pharmaceuticals Provides Update on Progress of Two Phase 3 Clinical Programs 2MAP Pharmaceuticals Provides Update on Progress of Two Phase 3 Clinical Programs 3Anacor Achieves Milestone from GSK for Boron-Based Systemic Antibacterial Product Candidate 2