Navigation Links
TGen, Scottsdale Healthcare study shows drug combination extends pancreatic cancer patient survival
Date:1/22/2013

was given only weeks to live when her Stage 4 pancreatic adenocarcinoma, a tumor the size of a golf ball, was first diagnosed in April 2012 nine months ago.

"If you had to live your life in a year, and that is all the time you have, wouldn't you do everything you could to experience this time," said Jacoby, who for nearly a year before her diagnosis had experienced night sweats, indigestion, stomach pains, neck and back pain, and an elevated white-blood count.

She began the treatment of Abraxane plus gemcitabine in May 2012 and continues on the medications, saying now that she "feels awesome, wonderful." She is scheduled to remain on the drug combination through May 2013.

"Life is priceless. No amount of money can be placed on life. I know I would be gone already if it was not for Dr. Von Hoff," said Jacoby, who also refers to him as "Dr. Von Hope."

The study showed significant improvement among some of the sickest patients including those with increased metastases. Significantly there was no increase in life-threatening toxicity. Other drug combinations that have demonstrated benefit have been limited by increased toxicities.

"This is a major improvement in a cancer with the lowest survival rates among all cancer types," said Dr. Ramesh Ramanathan, medical director of Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare and principal investigator for the clinical trial in the United States. "Advanced pancreatic cancer is fourth most common cause of cancer death in the United States and throughout the world. It is difficult to diagnose with a majority of the cases diagnosed at a late stage after the disease has already advanced."

Abraxane wraps traditional chemotherapy, paclitaxel, in near-nano sized shells of albumin, a protein that the tumor sees as food. The tumor uses various mechanisms to preferentially attract the albumin, which then acts like a "Trojan Horse" to release its package of
'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Mount Sinai grad student, 25, named to Forbes 30 Under 30 in Science and Healthcare
2. BUSM/VA Boston Healthcare System investigators identify new gene linked to PTSD
3. Pilot Results Move GHX Closer to Delivery of Healthcare Industrys First Implantable Device Supply Chain Solution
4. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
5. BGI, GE Healthcare team up on pioneering stem cell science projects
6. Premier Healthcare Renews Supplier Agreement with Masimo
7. Early Bird Offers on Healthcare and Biotechnology Conferences, Save Up To 20% by Registering with Global Information
8. Bioethics for Beginners: 60 Cases and Cautions from the Moral Frontier of Healthcare
9. Boston Healthcare Associates Roundtable Explores Challenges and Opportunities Surrounding the Value of Big Data within the Life Sciences
10. Early Bird Discounts Available on International Healthcare and Biotechnology Conferences, Save Up To $600 with Global Information
11. Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... Research and Markets ( http://www.researchandmarkets.com/research/lc9bnl/global_gesture ) ... Recognition Market in Automotive Sector 2014-2018" report to ... Gesture Recognition market in Automotive Sector to grow at ... Gesture recognition is the ability of a device ... individual. Gesture recognition technology can be 2D-based or 3D-based. ...
(Date:3/24/2015)... BEACH GARDENS, Fla. , March 24, 2015 ... biometric identity management solutions, today announced that its ... premium clothing accessory retailer Goorin Bros . ... The Crossmatch biometrics-based solution secures access to the ... from the increased risk of data breaches. ...
(Date:3/20/2015)... DUBLIN , Mar. 20, 2015 Research ... announced the addition of the "India Sensors ... their offering. The sensor market is ... through 2020 Consumer electronics, automotive, industrial ... for sensors in the country. In addition, adoption ...
Breaking Biology News(10 mins):Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3
... structure and function of cells and the process of ... constantly elongate and retreat in a thrashing frenzy of ... hair. Known prosaically as "dynamic instability," this ongoing rapid ... of microtubules in the cell. , For the first ...
... treatment of the sexual partners of infected patients. A ... to give their partners is more effective than traditional ... an article in the Sept. 1 issue of Clinical ... gonorrhea were more likely to see and talk to ...
... burrow into a tumor, seal the exits and detonate ... healthy cells unscathed. , MIT researchers have designed a ... drug-packing "nanocell" proved effective and safe, with prolonged survival, ... cancer--in mice. , The work will be reported in ...
Cached Biology News:The making and breaking of microtubules 2The making and breaking of microtubules 3The making and breaking of microtubules 4The making and breaking of microtubules 5Measurement Challenges In Detecting Cancer Biomarkers 2Measurement Challenges In Detecting Cancer Biomarkers 3MIT engineers an anti-cancer smart bomb 2
(Date:3/30/2015)... , March 30, 2015  Multiple new research ... affect several important health factors. From their impact on ... their positive effect on both gut health and vascular ... (EB) detail our latest understanding of walnuts, inner workings. ... Boston , this annual meeting attracts an international ...
(Date:3/30/2015)... 2015  NuGene International, Inc. ("NuGene") (OTCQB: NUGN), ... Inc. has added another internationally recognized researcher to ... an internationally recognized researcher in bio-inspired materials and ... Peking University, China , Professor ... of North Carolina, Chapel Hill. Following a postdoctoral ...
(Date:3/30/2015)... US-Australian drug discovery company, Novogen Ltd, (ASX:NRT; NASDAQ: ... University, on March 27 released pre-clinical data on experimental ... oral presentation by Professor Gil Mor MD ... Annual Scientific Meeting of the Society of Reproductive ... In both in vitro and in animal ...
(Date:3/30/2015)... March 30, 2015 /CNW/ - A new national Labour ... salaries and demographic profiles of new graduates entering the ... – Building Careers for New Grads in Biotech," is ... Research-Based Pharmaceutical Companies (Rx&D) and features data collected from ... wage subsidy program from 2013 to 2015. ...
Breaking Biology Technology:New Findings Support the Benefits of Eating Walnuts on Overall Health 2New Findings Support the Benefits of Eating Walnuts on Overall Health 3New Findings Support the Benefits of Eating Walnuts on Overall Health 4UCI Professor Zhibin Guan Joins NuGene Advisory Board 2UCI Professor Zhibin Guan Joins NuGene Advisory Board 3Yale University and Novogen Release Data on Cantrixil Mode of Action 2Yale University and Novogen Release Data on Cantrixil Mode of Action 3Yale University and Novogen Release Data on Cantrixil Mode of Action 4New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 2New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 3New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 4
... Wis. While Easter has come and gone, the ... can solve complex equations. , , Harmless Fluffy Bunnies , ... be traveling to Shanghai, China, from April 3 to 7 ... Computing Machinery's International Collegiate Programming Contest . The team ...
... year, I talked about merger mania in the Japanese pharmaceutical ... Though the Japanese were slow to participate in this industry, ... to a recent article in the March 2005 edition of ... biotech start-ups with an average of 20 employees per company ...
... scientist, and his colleagues want to develop a commercial drug ... Mithridion. Also, Wisconsin legislators are introducing a new computer privacy ... and the UW's Science Expeditions will be open to the ... Listen to this episode ...
Cached Biology Technology:'Fluffy Bunnies' ready for Shanghai programming competition 2'Fluffy Bunnies' ready for Shanghai programming competition 3Japanese biotech is booming and linked with Midwest 2Japanese biotech is booming and linked with Midwest 3
...
... stably express the regulatory GeneSwitch protein ... functionally tested for induction ability by ... vector pGene/V5-His/lacZ and by assaying for ... (Figure 1). These cell lines should ...
... Kit Includes: Sufficient library for ... x 10^9 independent sequences, -28 gIII ... DNA sequencing, -96 gIII Sequencing Primer ... Host E. coli strain ER2738, Control ...
... Materials for 15-20 enhancements when ... Western Blot Signal Enhancement System is designed to ... is an excellent tool for evaluating proteins with low ... to pre-treat membrane prior to blocking the membrane; 1x ...
Biology Products: