Navigation Links
TGen, Scottsdale Healthcare study shows drug combination extends pancreatic cancer patient survival
Date:1/22/2013

was given only weeks to live when her Stage 4 pancreatic adenocarcinoma, a tumor the size of a golf ball, was first diagnosed in April 2012 nine months ago.

"If you had to live your life in a year, and that is all the time you have, wouldn't you do everything you could to experience this time," said Jacoby, who for nearly a year before her diagnosis had experienced night sweats, indigestion, stomach pains, neck and back pain, and an elevated white-blood count.

She began the treatment of Abraxane plus gemcitabine in May 2012 and continues on the medications, saying now that she "feels awesome, wonderful." She is scheduled to remain on the drug combination through May 2013.

"Life is priceless. No amount of money can be placed on life. I know I would be gone already if it was not for Dr. Von Hoff," said Jacoby, who also refers to him as "Dr. Von Hope."

The study showed significant improvement among some of the sickest patients including those with increased metastases. Significantly there was no increase in life-threatening toxicity. Other drug combinations that have demonstrated benefit have been limited by increased toxicities.

"This is a major improvement in a cancer with the lowest survival rates among all cancer types," said Dr. Ramesh Ramanathan, medical director of Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare and principal investigator for the clinical trial in the United States. "Advanced pancreatic cancer is fourth most common cause of cancer death in the United States and throughout the world. It is difficult to diagnose with a majority of the cases diagnosed at a late stage after the disease has already advanced."

Abraxane wraps traditional chemotherapy, paclitaxel, in near-nano sized shells of albumin, a protein that the tumor sees as food. The tumor uses various mechanisms to preferentially attract the albumin, which then acts like a "Trojan Horse" to release its package of
'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Mount Sinai grad student, 25, named to Forbes 30 Under 30 in Science and Healthcare
2. BUSM/VA Boston Healthcare System investigators identify new gene linked to PTSD
3. Pilot Results Move GHX Closer to Delivery of Healthcare Industrys First Implantable Device Supply Chain Solution
4. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
5. BGI, GE Healthcare team up on pioneering stem cell science projects
6. Premier Healthcare Renews Supplier Agreement with Masimo
7. Early Bird Offers on Healthcare and Biotechnology Conferences, Save Up To 20% by Registering with Global Information
8. Bioethics for Beginners: 60 Cases and Cautions from the Moral Frontier of Healthcare
9. Boston Healthcare Associates Roundtable Explores Challenges and Opportunities Surrounding the Value of Big Data within the Life Sciences
10. Early Bird Discounts Available on International Healthcare and Biotechnology Conferences, Save Up To $600 with Global Information
11. Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... invisible is probably the ultimate form of camouflage: you ... And this strategy is not as uncommon as you ... Baltimore County, USA, explains that the larval life stages ... one part of the anatomy that most creatures cannot ... eyes have to shield each individual eye unit with ...
(Date:9/18/2014)... the protective tentacles of host anemones, but new research ... kilometres across the open ocean. Although the process of ... is the first time that the high level exchange ... Dr Steve Simpson, Senior Lecturer in Marine Biology and ... from the Australian Research Council Centre of Excellence for ...
(Date:9/17/2014)... UCLA atmospheric scientists were instrumental in the creation of ... tool to classify the fire threat potential of the ... a spark into an inferno. The index was introduced ... with UCLA and San Diego Gas and Electric. , ... to "extreme" that will be used to help fire ...
Breaking Biology News(10 mins):Transparent larvae hide opaque eyes behind reflections 2Expedition finds Nemo can travel great distances to connect populations 2Expedition finds Nemo can travel great distances to connect populations 3UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2
... suggest that patients with aggressive non-Hodgkin,s lymphoma in the ... researchers say. At the ESMO Conference Lugano (ECLU) ... group headed by Prof. Hamdy Azim from Cairo University ... rather than every 3 weeks as usual, improved treatment ...
... Since earliest recorded history, and presumably beyond, humans have ... of winged creatures around them, and unfailingly ended in ... particularly similar to nature,s fliers, and today there is ... chopper and the humble bumblebee, despite similar flight patterns. ...
... your imagination run away with you may actually influence ... University has found that mental imagery--what we see with ... The research was published online June 26 by the ... imagery leads to a short-term memory trace that can ...
Cached Biology News:New treatment approach promising for lymphoma patients in the developing world 2Want to fly? Don't copy the birds and the bees 2'Mind's eye' influences visual perception 2'Mind's eye' influences visual perception 3
(Date:9/19/2014)... NYU Langone Medical Center have found a way to ... turning adult cells into so-called pluripotent stem cells by ... new technique in mice, the researchers increased the number ... more than 20-fold compared with the standard method. They ... should generally accelerate research aimed at using stem cells ...
(Date:9/19/2014)... 2014  Nektar Therapeutics (NASDAQ: NKTR ... the analgesic profiles of a series of the ... molecules. The preclinical research candidates were created using ... The analgesic properties of kappa receptor agonism ... Kappa opioid receptors are expressed in the ...
(Date:9/19/2014)... , September 19, 2014 ... and Markets ( http://www.researchandmarkets.com/research/b2jxhs/micro_market ) has announced the addition ... Chromatography Columns"  report to their offering.  ... market is one of the fastest-growing segments in ... $1.2 billion in 2013, and expected to reach ...
(Date:9/18/2014)... About POCT POCT, ... clinical laboratory. It helps in making fast clinical ... medication. POCT is gaining popularity due to the ... as diabetes, heart disease, and obesity. It is ... to minimize errors during the diagnosis of patients. ...
Breaking Biology Technology:NYU Langone scientists report reliable and highly efficient method for making stem cells 2NYU Langone scientists report reliable and highly efficient method for making stem cells 3Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 2Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 3Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 4Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 5Micro Market Monitor : Global Pre-packed Chromatography Columns 2POCT Market in China 2014-2018 2
... EUGENE, Ore. -- A collaborative Oregon State University-University of ... National Science Foundation grant in 2008, is moving into ... grant. The new NSF funding, awarded through its ... for Sustainable Materials Chemistry to expand research and development ...
... Medical Center in Tucson (UMC) is validating the VENTANA INFORM ... on the BenchMark XT automated slide staining instrument to help ... effort to change the paradigm for targeted treatment therapies. The ... of the Roche group, is the first fully automated assay ...
... For years, dieters and researchers around the world have ... (human Chorionic Gonadotropin) supplements can have on the battle against ... by Creative Bioscience, a leader in diet support products ... take advantage of the powerful metabolic boost of hCG without ...
Cached Biology Technology:Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 2Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 3Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 4Early Adopter of INFORM HER2 Dual ISH Assay Optimistic About Impact on Patient Care, Hospital Bottom Line 2Early Adopter of INFORM HER2 Dual ISH Assay Optimistic About Impact on Patient Care, Hospital Bottom Line 3Early Adopter of INFORM HER2 Dual ISH Assay Optimistic About Impact on Patient Care, Hospital Bottom Line 4Hormone-free hCG Zero Capsules™ Boost Metabolism to Enhance Weight Loss Without Starvation 2Hormone-free hCG Zero Capsules™ Boost Metabolism to Enhance Weight Loss Without Starvation 3Hormone-free hCG Zero Capsules™ Boost Metabolism to Enhance Weight Loss Without Starvation 4
... Analyzer for General Chemistries, Specialty Chemistries, QC, Reagent Development, Pharmaceutical Development, Physician Owned Labs, Drugs ... user-selectable wavelengths. ... ... ...
Recorder REC-111 single-channel, 1. Category: Chromatography Systems & Accessories, Systems....
2,4,6, Trinitrophenyl hapten is conjugated to lipopolysaccharide (LPS)....
For the quantitative determination of cyclic AMP (cAMP) concentrations in cell culture supernates, serum, plasma, saliva, urine and cell lysates....
Biology Products: