Navigation Links
TGen, Scottsdale Healthcare study shows drug combination extends pancreatic cancer patient survival
Date:1/22/2013

SCOTTSDALE, Ariz. Jan. 22, 2013 A multi-center Phase III clinical trial demonstrates that Abraxane (nab-paclitaxel) plus gemcitabine is the first combination of cancer drugs to extend survival of late-stage pancreatic cancer patients compared to standard treatment.

The MPACT (Metastatic Pancreatic Adenocarcinoma Clinical Trial) study was led by physicians from Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen).

Their findings show that Abraxane plus gemcitabine was well tolerated and resulted in clinically meaningful outcomes compared to gemcitabine alone, the current standard of care. The study abstract was released today and the data will be presented at the American Society of Clinical Oncology (ASCO) 2013 Gastrointestinal Cancers annual meeting Jan. 25 in San Francisco.

"We are ecstatic that this clinical trial of Abraxane plus gemcitabine improves survival for patients with advanced stage IV pancreatic cancer," said Dr. Daniel Von Hoff, international lead investigator for MPACT, chief scientific officer for Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, and TGen's Physician-In-Chief. "It once again demonstrates that laboratory science based medicine can make a difference for patients."

MPACT is the largest phase III clinical trial completed in advanced pancreatic cancer with more than 800 patients. Findings from the study showed a 59 percent increase in one-year median survival rates from less than a quarter of the patients (22 percent) to more than a third (35 percent). The two-year survival rate for this cancer is negligible, less than 4 percent, but that more than doubles (9 percent) with the nab-paclitaxel/gemcitabine combination.

One of those patients was Lynne Jacoby, 48, of Phoenix, who works as a director of compliance for a healthcare company. Jacoby
'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Mount Sinai grad student, 25, named to Forbes 30 Under 30 in Science and Healthcare
2. BUSM/VA Boston Healthcare System investigators identify new gene linked to PTSD
3. Pilot Results Move GHX Closer to Delivery of Healthcare Industrys First Implantable Device Supply Chain Solution
4. VTT and GE Healthcare developing novel biomarkers to predict Alzheimers disease
5. BGI, GE Healthcare team up on pioneering stem cell science projects
6. Premier Healthcare Renews Supplier Agreement with Masimo
7. Early Bird Offers on Healthcare and Biotechnology Conferences, Save Up To 20% by Registering with Global Information
8. Bioethics for Beginners: 60 Cases and Cautions from the Moral Frontier of Healthcare
9. Boston Healthcare Associates Roundtable Explores Challenges and Opportunities Surrounding the Value of Big Data within the Life Sciences
10. Early Bird Discounts Available on International Healthcare and Biotechnology Conferences, Save Up To $600 with Global Information
11. Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... McGill University and the Quebec government have discovered ... Canadian Journal of Fisheries and Aquatic Sciences . ... cleansers, or industrial cleansers, to which they are ... size and buoyancy, they may readily pass through ... contaminant in the world,s oceans, but have only ...
(Date:9/18/2014)... DNA, tiny strands of nucleic acid that contain instructions ... genetic data, our DNA is copied into RNA molecules, ... tasks in our cells. , Several years ago, ... all other known RNAs, this molecule is circular, and ... little has been known about how they are produced. ...
(Date:9/18/2014)... celebrated tonight at the third annual Golden Goose Award ... premature infants and in paving the way for the ... supported by the National Science Foundation, the National Institutes ... be honored at a ceremony at the Library of ... of Congress will be on hand to help present ...
Breaking Biology News(10 mins):Microplastic pollution discovered in St. Lawrence River sediments 2Scientists find how mysterious 'circular RNA' is formed, claim muscular dystrophy link 23rd annual Golden Goose award ceremony honors 8 researchers; Unusual work had big results 2
... will join researchers from around the world to celebrate ... treaty designed to reduce the hole in Earth,s protective ... the meeting from Sept. 23-26 in Athens, Greece. NASA ... the recovery of the ozone layer. "The Montreal ...
... (UWM) are working with local company PhysioGenix to investigate ... researching diseases like depression, anxiety, schizophrenia and ADHD. ... by researchers at the Medical College of Wisconsin (MCW) ... diseases. Called consomic rats, they were produced by replacing ...
... Fred Dryer has a lofty goal: end the nation,s ... potentially major benefits for energy security and the environment ... knowledge of jet fuels while developing practical, innovative energy ... sources feasible, they need to be compatible with petroleum ...
Cached Biology News:NASA keeps eye on ozone layer amid Montreal Protocol's success 2NASA keeps eye on ozone layer amid Montreal Protocol's success 3A new kind of rat model 2Green skies: Engineer's work may reduce jet travel's role in global warming 2Green skies: Engineer's work may reduce jet travel's role in global warming 3Green skies: Engineer's work may reduce jet travel's role in global warming 4
(Date:9/18/2014)... (PRWEB) September 18, 2014 ... urological and interventional radiology products and services, announced ... as cryotherapy and cryoablation) versus external beam radiotherapy ... of the American Urological Association (MAAUA) Annual Meeting ... "Comparing Relative Effectiveness of Cryosurgery and External Beam ...
(Date:9/18/2014)... DALLAS , Sept. 18, 2014 /PRNewswire-iReach/ -- ... and China Acetic Acid Industry" and "2014 Deep ... Industry" reports to its research database. ... 2014 Deep Research Report on Global and China ... research report on China ...
(Date:9/18/2014)...  Health Enhancement Products, Inc. (OTCQB: HEPI), a ... and metabolic processes, is pleased to announce the addition of ... Nola E. Masterson , a California ... September 17, 2014. "We,re very pleased and ... states Andrew Dahl , President and CEO. "She joins ...
(Date:9/18/2014)... Texas Governor Rick Perry, Texas ... Health Science Center CEO Brett Giroir, M.D., and ... Human Services (HHS), State of Texas and biopharmaceutical ... vaccine manufacturing facility in Bryan, Texas, which when ... Texas A&M Biocorridor – a rapidly evolving hub ...
Breaking Biology Technology:HealthTronics Announces Data Comparing Cryotherapy Versus Radiation for Treating Prostate Cancer Poster Presented at the American Urological Association Regional Meeting 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4Health Enhancement Announces New Board Member In Advance Of Annual Shareholder Meeting 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 3Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 4
... 1 Alfacell Corporation,(Nasdaq: ACEL ) today ... on July 29, 2008 notifying the Company that ... Market. On June 25,2008, NASDAQ notified the Company ... been below the minimum $35 million required for ...
... (Nasdaq:,NVAX) announced today that it has completed the ... by issuing common stock,and warrants (the "units") from ... units to certain current and new institutional,shareholders and ... comprised,of one share of common stock and a ...
... Sponsorship Agreement Promotes International Medical Education, Helps ... Break Down Language ... the world have a potent new ally to help them,integrate ... http://www.newscom.com/cgi-bin/prnh/20080624/NETU078LOGO ), Dr. Peter M. Leitner, President ...
Cached Biology Technology:Alfacell Receives NASDAQ Delisting Letter 2Alfacell Receives NASDAQ Delisting Letter 3Novavax Announces Closing of $18 Million Registered Direct Offering 2Novavax Announces Closing of $18 Million Registered Direct Offering 3MaxWell Biocorporation, LLC, and International Medical Information Technologies, Inc., Announce Partnership 2
Human Legumain Affinity Purified Polyclonal Ab...
Human Siglec-9 Biotinylated Affinity Purified Pab...
TUNEL Apoptosis Detection Kit...
... NOS activity by monitoring the conversion of ... simple, sensitive, and specific for NOS activity ... and purified enzyme preparations. The kit includes ... reactions. Radiolabeled arginine and NADPH are not ...
Biology Products: