Navigation Links
T cell discovery shows promise for Type 1 diabetes treatment: UBC-CFRI study
Date:10/5/2010

A research team from the University of British Columbia and the Child & Family Research Institute (CFRI) at BC Children's Hospital has identified the role of a type of T cell in type 1 diabetes that may lead to new treatment options for young patients.

Also known as juvenile diabetes, type 1 diabetes is an autoimmune disease primarily affecting children and young adults. In patients with type 1 diabetes, the body attacks itself by destroying insulin-producing cells in the pancreas that regulate glucose, or blood sugar.

Led by Rusung Tan, a Pathology professor in the UBC Faculty of Medicine and co-head of the Immunity in Health and Disease research cluster at CFRI, the research team has identified the increased presence of Th17 cells, a type of T cell discovered in 2005, in children newly diagnosed with type 1 diabetes.

"T cells are white blood cells and key members of the immune system that control infections," says Tan, who is also a member of the Department of Pathology & Laboratory Medicine at BC Children's Hospital and a senior scholar of the Michael Smith Foundation for Health Research. "In healthy individuals, Th17 cells provide a strong defence against bacteria and viruses by guiding the immune system to strongly attack infected targets within our bodies."

However, Th17 has been associated with other autoimmune diseases such as Crohn's disease, which suggests they can play a harmful role. Treatments designed to block Th17 cells are in clinical trials for these diseases.

"The elevated levels of Th17 cells in type 1 diabetes patients suggest that these cells may also play a key role in the early development of this disease in young patients," says Tan. "This discovery opens the door to new treatments for childhood diabetes that target Th17 cells."


'/>"/>

Contact: Brian Lin
brian.lin@ubc.ca
604-822-2234
University of British Columbia
Source:Eurekalert

Page: 1

Related biology news :

1. Research breakthrough hailed on the anniversary of gene discovery
2. Discovery of a cell that suppresses the immune system
3. Census of Marine Life celebrates decade of discovery
4. Discovery of key pathway interaction may lead to therapies that aid brain growth and repair
5. Biofuel from inedible plant material easier to produce following enzyme discovery
6. Discovery offers hope of saving sub-Saharan crops from devastating parasites
7. Gene discovery holds key to growing crops in cold climates
8. First discovery of bilirubin in a flower announced
9. Report: Discovery networks hostage-taking a rare terror event
10. New discovery suggests our lungs are innately prone to silicosis and related diseases
11. A plan to promote sustainable US scientific discovery and innovation in the 21st century is proposed in OMICS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2016)... , March 3, 2016  FlexTech, a SEMI ... categories of Innovation, Research & Development, Leadership in Education, ... This is the 9 th year of the ... of companies and individuals from past years . ... on a pre-described set of criteria, by a panel ...
(Date:3/3/2016)... and DE SOTO, Kansas , March ... Detection Plus® to offer Oncimmune,s Early CDT®-Lung, a ... early detection of lung cancer Early CDT®-Lung ... and individuals. --> Early CDT®-Lung test to ... --> Oncimmune, a leader in early cancer ...
(Date:3/2/2016)... 2016 http://www.researchandmarkets.com/research/cmt3hk/global_biometrics ) ... "Global Biometrics as a Service Market 2016-2020" ... --> http://www.researchandmarkets.com/research/cmt3hk/global_biometrics ) has announced the ... a Service Market 2016-2020" report to ... and Markets ( http://www.researchandmarkets.com/research/cmt3hk/global_biometrics ) has announced ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... ... May 03, 2016 , ... According to world renowned prostate cancer surgeon, ... patients traditionally had two main treatment options: surgery or radiation. Based on a patient’s ... New technology has enabled doctors to administer higher doses of radiation to ...
(Date:5/2/2016)... ... , ... StarNet Communications Corp, ( http://www.starnet.com/ ) a leading publisher of remote ... modules to its flagship X-Win32 PC X server. The new modules enable X-Win32 ... PC over encrypted SSH. , Traditionally, users of PC X servers deploy the XDMCP ...
(Date:4/29/2016)... , ... April 29, 2016 , ... ... devices used in spinal surgical procedures, today announced the completion of a significant ... proposition for current and future customers and partners. Kohlberg & Company, L.L.C. ...
(Date:4/29/2016)... ... ... Implant Systems announced today that the two-level components for the Revolution™ Spinal System were ... components expand the capabilities of the system and allow Revolution™ to be utilized for ... company has seen significant sales growth in 1Q 2016, and the system is currently ...
Breaking Biology Technology: