Navigation Links
Syracuse University biologist discovers key regulators for biofilm development
Date:6/24/2011

idn't know how the EBP regulatory circuit was put together." Garza's team has also begun to identify the signals that activate the EBP circuitry and the corresponding biofilm genes. Those studies are forthcoming.

The work to uncover how biofilms are genetically initiated is key to developing new ways to prevent and/or treat infected surfaces, Garza says. Bacteria are stimulated to organize into biofilms by several mechanisms, including starvation, high nutrient levels, tissue recognition, and quorum or cell-density signaling. Because it takes a lot of energy to organize, bacteria need to be certain conditions are optimal before initiating the biofilm process.

For example, Garza explains, bacterial cells can recognize desirable host tissue, such as lung tissue. Once there, the cells look around to see if enough of their buddies are around to form a biofilm. In this case, both tissue recognition and quorum signaling is at work in initiating the process.

"Unfortunately, biofilms can be up to a thousand times more antibiotic resistant than free-living bacteria," Garza says. "Once established, biofilms are extremely resistant to killing agentschemicals, cleaners, antibiotics. The key to preventing their development is in understanding how they get started."


'/>"/>

Contact: Judy Holmes
jlholmes@syr.edu
315-443-8085
Syracuse University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Syracuse University scientists discover new hitch to link nerve cell motors to their cargo
2. Syracuse University research team shapes cell behavior research
3. Syracuse University team develops functionally graded shape memory polymers
4. Falling in love more scientific than you think, according to Syracuse University professor
5. Syracuse University partners with Arden-Fox to advance DODs Net Zero Energy Initiative
6. Syracuse University researchers discover new way to attack some forms of leukemia
7. Guy Harvey Ocean Foundation funds University of Miamis R.J. Dunlap Program
8. Ben-Gurion University team presents environment movement report to Israels Knesset
9. Hong Kong University leads the genomics research of scarlet fever pathogen
10. Not-so-sweet potato from Clemson University, USDA resists pests, disease
11. University of Texas at Austin professor receives Donald L. Katz Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2014)... Mothers give a newborn baby a gift of ... system. But antibiotics, used to fend off infection, ... leaving already-vulnerable premature babies more susceptible to dangerous ... neonatology researchers at The Children,s Hospital of Philadelphia ... revealing how gut microbes play a crucial role ...
(Date:4/18/2014)... decades, scientists have used techniques like X-ray crystallography and ... into the atomic structure of molecules, but such efforts ... demand large quantities of a specific molecule and often ... making it all but impossible to peer into the ... those problems may soon be a thing of the ...
(Date:4/18/2014)... Durham, NC Seeds that sprout as soon as they,re ... plants need to be more careful. In the wild, a ... rainy day would risk disaster. More than just an insurance ... out that seed dormancy has long-term advantages too: Plants ... give rise to more species, finds in a team of ...
Breaking Biology News(10 mins):Study of gut microbes, antibiotics: Clues to improving immunity in premature infants 2MRI, on a molecular scale 2MRI, on a molecular scale 3Plants with dormant seeds give rise to more species 2
... antibiotic used to boost organ survival in transplant ... the heart against tissue damage following acute heart ... Journal of Molecular and Cellular Cardiology, the official ... researchers demonstrated for the first time that pretreatment ...
... to change their spots, but corals can change their skeletons, ... composition of the seawater around them. , That's the startling ... in the July issue of the journal Geology. , ... the first known case of an animal altering the composition ...
... University in St. Louis and their collaborators from Taiwan ... varieties and have determined that the crop was domesticated ... Jason Londo, Washington University in Arts & Sciences biology ... Washington University Spencer T. Olin Professor of Biology in ...
Cached Biology News:New study shows antibiotic may protect the heart 2Corals switch skeleton material as seawater changes 2Corals switch skeleton material as seawater changes 3Biologists find regions of rice domestication 2
(Date:1/15/2014)... Jacobs Automotive, a group of car dealerships headquartered in ... Blood Center and offering free oil change coupons for participation ... Jan. 18 at the Bill Jacobs Cadillac and Chevrolet location ... http://photos.prnewswire.com/prnh/20140115/MN46637 )  The Bill Jacobs Auto annual ...
(Date:1/15/2014)... California , January 15, 2014 Oxford ... today announced the appointment of Thomas C Reynolds MD, PhD ... years, development experience gained in the biotechnology industry, most recently ... am delighted to welcome Tom at this transformative time for ...
(Date:1/15/2014)... Two champions of science, technology, engineering, and ... annual competition for middle and high school students designed ... study. The competition presents students with real-world problems experienced ... Mathematics, and Sciences is a program administered by ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider of ... of tinnitus. Patients listen to sound therapy that is ... of weeks to months, their tinnitus volume decreases. , AudioNotch ... Music and Notched White Noise. Now, AudioNotch is pleased to ...
Breaking Biology Technology:Join the Bill Jacobs Auto blood drive and receive a free oil change 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5
... Therapeutics, Inc.,(Nasdaq: TPTX ) today announced that ... in certain royalty amounts that may become payable to ... and tezampanel,should either or both gain regulatory approval. Specifically, ... points and the middle tier,royalty rate will be reduced ...
... Pa., Nov. 25 Tengion Inc., a clinical stage regenerative medicine ... that Steven Nichtberger, M.D., President and Chief Executive Officer of Tengion, ... Tuesday, December 2, 2008 at 9:50 a.m. EST at The Palace ... , About Tengion , ...
... 25 /PRNewswire-Asia/ -- ScinoPharm, an active,pharmaceutical ingredient (API) ... 7,435,818 entitled "Novel Crystal Forms of Irinotecan,Hydrochloride." The ... hydrochloride and processes for their preparation as well ... of treating,metastatic carcinoma of the colon or rectum ...
Cached Biology Technology:TorreyPines Therapeutics Enters into Agreement to Reduce Royalty Rates and Delay Clinical Milestone Payments Due to Eli Lilly for NGX426 and Tezampanel 2ScinoPharm Granted US Patent for Novel Crystal Forms 2
... JMP 6 delivers enhanced statistics and ... and quality improvement managers. As an ... JMP 6 simplifies statistics for novice ... needed by experts. It offers a ...
... F1 antigen, Monoclonal Antibody, Unconjugated ... Use at an assay dependent dilution. ... dilution. WB: Use at an assay ... kDa. Not tested in other applications. ...
...
Collected from calves that are 10 days old or less. Sterile, cell culture tested, US Origin...
Biology Products: