Navigation Links
Syracuse University biologist discovers key regulators for biofilm development
Date:6/24/2011

They can be found everywhereorganized communities of bacteria sticking to surfaces both inside and outside the body. These biofilms are responsible for some of the most virulent, antibiotic-resistant infections in humans; however, scientific understanding of how these communities develop is lacking.

A recent study led by a Syracuse University biologist sheds new light on the process. The scientists discovered that a complex cascade of enhancer binding proteins (EBPs) is responsible for turning on genes that initiate the formation of a biofilm. The study was published June 13 in the Proceedings of the National Academy of Sciences, one of the world's most-cited multidisciplinary scientific serials. The National Science Foundation is funding the research (link to article: http://www.pnas.org/content/early/2011/06/07/1105876108.abstract?sid=dbfeeb94-6f1e-44c8-b610-d39a98acbd88).

"We've discovered a complex regulatory cascade of EBPs that is designed to be highly responsive to environmental signals," says Anthony Garza, associate professor of biology in SU's College of Arts and Sciences and corresponding author for the study. "The regulatory circuit we identified is very different from that which has previously been seen." Garza's research team includes scientists from the University of Miami School of Medicine, the University of Wisconsin-Madison, and Stanford University School of Medicine.

Garza's team discovered that the regulatory network that signals biofilm development is quite complex and akin to that which is normally found in higher organisms. "Bacterial cells that form biofilms require cooperative behavior similar to cells in more complex organisms," he says. "We knew EBPs were important in initiating biofilm development, and that there was a connection between EBPs and specific biofilm genes. But we d
'/>"/>

Contact: Judy Holmes
jlholmes@syr.edu
315-443-8085
Syracuse University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Syracuse University scientists discover new hitch to link nerve cell motors to their cargo
2. Syracuse University research team shapes cell behavior research
3. Syracuse University team develops functionally graded shape memory polymers
4. Falling in love more scientific than you think, according to Syracuse University professor
5. Syracuse University partners with Arden-Fox to advance DODs Net Zero Energy Initiative
6. Syracuse University researchers discover new way to attack some forms of leukemia
7. Guy Harvey Ocean Foundation funds University of Miamis R.J. Dunlap Program
8. Ben-Gurion University team presents environment movement report to Israels Knesset
9. Hong Kong University leads the genomics research of scarlet fever pathogen
10. Not-so-sweet potato from Clemson University, USDA resists pests, disease
11. University of Texas at Austin professor receives Donald L. Katz Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 2014 The Defense Logistics Agency is insourcing its ... counterfeit microcircuits from entering into its supply chain. ... anti-counterfeit initiative dubbed DNA marking. The capability will validate ... throughout the supply chain. The new quality control measures ...
(Date:12/15/2014)... Research and Markets ( http://www.researchandmarkets.com/research/87pph8/global_facial ) has ... Market 2015-2019" report to their offering. ... is a technology used for the identification of individuals. ... a person such as nose, jaw edges, mouth, and ...
(Date:12/10/2014)... Dec. 8, 2014 You,ve been here before: you desperately need ... password, site key or the answer to your secret question. What,s ... Today, Hoyos Labs , a digital infrastructure security company, ... to the frustration that comes with usernames, passwords and PINs – ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... Duke University Medical Center have pinpointed a fungal ... in the development and virulence of Alternaria brassicicola. ... causes black spot disease on most cultivated Brassica ... many economically important crops including canola, cabbage and ...
... health of Florida's coral reef as part of a field ... was the first comprehensive assessment of the resiliency of reefs ... miles from Martin County to the Dry Tortugas in the ... are resilient to environmental changes and impacts. The work may ...
... An international team of scientists has published the ... of plant pathogens called Phytophthora--a name that literally ... of fungus-like Phytophthora (pronounced "fy-TOFF-thor-uh") attack a broad ... forestry and nursery industries hundreds of billions of ...
Cached Biology News:Tearing down the fungal cell wall 2Tearing down the fungal cell wall 3NASA satellite data helps assess the health of Florida's coral reef 2NASA satellite data helps assess the health of Florida's coral reef 3Genome info from 'plant destroyers' could save trees, beans and chocolate 2
(Date:1/22/2015)... January 22, 2015 zFlo Motion , ... to announce an exciting product from a new partner. ... solutions over the past 15 years, with offerings in the ... their 3D IMU system (inertial measurement unit), iSen, is opening ...
(Date:1/22/2015)... Denville, NJ (PRWEB) January 22, 2015 ... shearing technologies such as the Bioruptor® and complete ... semi-automation system for chromatin immunoprecipitation, alleviating the need ... reagents and controls needed for ChIP of histones ...
(Date:1/22/2015)... , a precision medicine software company that has developed a ... genomic, imaging and other biomedical data in research and clinical ... CEO of Aspera, an IBM Company, to its board as ... "We are pleased to welcome Michelle to ...
(Date:12/24/2014)... NEW YORK , Dec. 24, 2014 ... patient care in critical areas, announced the closing of an ... warrants to purchase up to an aggregate 3,500,000 shares of ... and $.01 per warrant.  The warrants have a per share ...
Breaking Biology Technology:3D Motion Capture Just Got Easy 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2GenoSpace Expands Board with Appointment of Michelle Munson 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3
... ... Medicine is set to revolutionize the healthcare industry. As our knowledge of genetics and ... , ... (PRWEB) May 18, 2010 -- The era of Personalized Medicine is set to revolutionize ...
... 18, 2010 Among more than 5000 poster,abstracts, Aprea AB has ... Oncology (ASCO) Meeting in Chicago . The,presentation will describe the scientific ... candidate APR-246. , , , ... Aprea,s drug candidate APR-246 belongs to a new class of ...
... NINGBO, China , May ... Ltd. (TAIJI),s FGD (Flue-gas desulfurization),technology was officially put into ... project, TAIJI chose to use steel slag as an ... desulfurization. In,comparison to the use of lime agents, the ...
Cached Biology Technology:Arrowhead Releases New Report Assessing State of Personalized Medicine Market 2Arrowhead Releases New Report Assessing State of Personalized Medicine Market 3Aprea to Present Phase I/II Trial Design 2Aprea to Present Phase I/II Trial Design 3TAIJI Announces Official Operation of Its Sintering FGD Project for Tangshan 2
... Shakers combine high durability and capacity ... of use. The patented triple-counterbalanced heavy-duty ... to run at high speed with ... temperature range is delivered with tight ...
The 891 45° Fixed Angle Rotor is designed to provide aerosol containment and can be removed from a centrifuge (seal entact) and opened under an environmental hood....
... have the durability to run ... and the uniformity and contamination ... applications. Heavily built with ... stackers are designed for ease ...
Request Info...
Biology Products: