Navigation Links
Syracuse University biologist discovers key regulators for biofilm development
Date:6/24/2011

They can be found everywhereorganized communities of bacteria sticking to surfaces both inside and outside the body. These biofilms are responsible for some of the most virulent, antibiotic-resistant infections in humans; however, scientific understanding of how these communities develop is lacking.

A recent study led by a Syracuse University biologist sheds new light on the process. The scientists discovered that a complex cascade of enhancer binding proteins (EBPs) is responsible for turning on genes that initiate the formation of a biofilm. The study was published June 13 in the Proceedings of the National Academy of Sciences, one of the world's most-cited multidisciplinary scientific serials. The National Science Foundation is funding the research (link to article: http://www.pnas.org/content/early/2011/06/07/1105876108.abstract?sid=dbfeeb94-6f1e-44c8-b610-d39a98acbd88).

"We've discovered a complex regulatory cascade of EBPs that is designed to be highly responsive to environmental signals," says Anthony Garza, associate professor of biology in SU's College of Arts and Sciences and corresponding author for the study. "The regulatory circuit we identified is very different from that which has previously been seen." Garza's research team includes scientists from the University of Miami School of Medicine, the University of Wisconsin-Madison, and Stanford University School of Medicine.

Garza's team discovered that the regulatory network that signals biofilm development is quite complex and akin to that which is normally found in higher organisms. "Bacterial cells that form biofilms require cooperative behavior similar to cells in more complex organisms," he says. "We knew EBPs were important in initiating biofilm development, and that there was a connection between EBPs and specific biofilm genes. But we d
'/>"/>

Contact: Judy Holmes
jlholmes@syr.edu
315-443-8085
Syracuse University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Syracuse University scientists discover new hitch to link nerve cell motors to their cargo
2. Syracuse University research team shapes cell behavior research
3. Syracuse University team develops functionally graded shape memory polymers
4. Falling in love more scientific than you think, according to Syracuse University professor
5. Syracuse University partners with Arden-Fox to advance DODs Net Zero Energy Initiative
6. Syracuse University researchers discover new way to attack some forms of leukemia
7. Guy Harvey Ocean Foundation funds University of Miamis R.J. Dunlap Program
8. Ben-Gurion University team presents environment movement report to Israels Knesset
9. Hong Kong University leads the genomics research of scarlet fever pathogen
10. Not-so-sweet potato from Clemson University, USDA resists pests, disease
11. University of Texas at Austin professor receives Donald L. Katz Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... New York , July 7, 2014 ... by Transparency Market Research "Electronic Access Control Systems Market ... 2014 - 2019," the global Electronic Access Control systems ... and is expected to grow at a CAGR of ... value of USD 31,187.8 million in 2019. ...
(Date:7/10/2014)... belongs to the large, mainly tropical flowering plant family ... in the family rely on bees for their pollination. Only ... or vertebrates. The flowers of Axinaea appear in ... petals of the different species are pink, yellow, orange or ... the contrasting colours of their bulbous appendages. The pollination mechanism ...
(Date:7/10/2014)... has helped stabilize or even improve the state ... the situation in the Mediterranean has deteriorated over ... evaluating nine fish species reported in the Cell ... 10, scientists call for stringent monitoring of Mediterranean ... advanced management plans in Mediterranean waters. , Their ...
Breaking Biology News(10 mins):Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 2Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 3Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 4Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 5Novel type of bird pollination mechanism discovered in South America 2Mediterranean fish stocks show steady decline 2
... 20, 2013 Market news updates for advancing ... Inc. (OTCQB: NXTD), Apple Inc. (NASDAQ: AAPL ), ... CSCO ) and NQ Mobile Inc. (NYSE: NQ) ... published a report on NXT-ID, Inc., (OTCQB: NXTD) featuring the ...
... of all humans are persistently colonized with Staphylococcus aureus ... of the major sources of hospital-acquired infections, including the antibiotic-resistant ... discovered one of the keys to the immense success of ... immune defense mechanism and use it to destroy white blood ...
... fattening than others? What about the risks of bariatric ... (ASN) on December 5-7 for answers to these questions ... Nutrition Conference. The 3-day program delivers valuable ... satellite sessions, and networking opportunities. Credentialed media, science writers ...
Cached Biology News:Biometric-Mobile Wallet Technology Takes Aims at a Target Market Of Nearly $1Billion Potential 2Biometric-Mobile Wallet Technology Takes Aims at a Target Market Of Nearly $1Billion Potential 3Biometric-Mobile Wallet Technology Takes Aims at a Target Market Of Nearly $1Billion Potential 4Biometric-Mobile Wallet Technology Takes Aims at a Target Market Of Nearly $1Billion Potential 5Staphylococcus aureus bacteria turns immune system against itself 2Advances and Controversies in Clinical Nutrition: Diet, Technology and Practice 2
(Date:7/10/2014)... Hall effect in bilayer graphene and shown that this ... electric field. , The fractional quantum Hall effect, ... are exposed to large magnetic fields, is a striking ... behave as a single system. However, while the basic ... of this collective behavior remain not well understood, in ...
(Date:7/10/2014)... out for crude 3-D glasses, polarized glasses, and ... basic devices, used to trick the brain into ... rendered obsolete with the introduction of new holography ... TAU doctoral students Yuval Yifat, Michal Eitan, and ... on nanoantennas that could be used for security ...
(Date:1/15/2014)... assembling a club sandwich at the nanoscale, National ... succeeded in crafting a uniform, multi-walled carbon-nanotube-based coating ... used in upholstered furniture and other soft furnishings. ... was reduced 35 percent compared with untreated foam. ...
(Date:1/15/2014)... PA (PRWEB) January 15, 2014 The Pittcon ... publisher of Food Safety Tech , an e-Journal and ... signed an agreement for the second year for the co-location ... Pittcon 2014. The partnership provides that the registration fee to ...
Breaking Biology Technology:Columbia researchers observe tunable quantum behavior in bilayer graphene 2Columbia researchers observe tunable quantum behavior in bilayer graphene 3Projecting a 3-dimensional future 2Projecting a 3-dimensional future 3Layered security: Carbon nanotubes promise improved flame-resistant coating 2Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3
... Disease Altering Treatment Shows Ability to Prevent HIV ... VIRxSYS Corporation, a,privately held company developing gene therapies ... Phase II trial of VRX496, a gene,therapy for ... Conference on,Retroviruses and Opportunistic Infections (CROI) in Boston, ...
... Strengthening PPD,s presence in Eastern Europe, WILMINGTON, N.C., ... has signed an agreement to purchase InnoPharm,Ltd., an independent ... acquisition will expand PPD,s global reach with,established offices in ... CROs in Russia, InnoPharm was a pioneer in the,implementation ...
... (Nasdaq: IDIX ) announced today that Idenix management,will ... & Investor,Conference on Tuesday, February 12, 2008 at 9:30 ... the Waldorf-Astoria Hotel in New York, NY., The ... accessed,under "Calendar of Events" in the Idenix Investor Center ...
Cached Biology Technology:VIRxSYS Announces Interim Results from VRX496 Gene Therapy Phase II Trial 2PPD to Acquire InnoPharm Ltd. 2PPD to Acquire InnoPharm Ltd. 3
...
... Antibody Validation Service enables early selection ... development by providing quantitative data for ... of each antibody. Furthermore quantitative antibody ... off-target activity of your antibodies., The ...
... western blotting. Get results sooner and save hours ... detection. Eliminates the need for a membrane transfer ... reagents are ready-to-use. No reagents to prepare or ... reagents required. Guarantees a simple to perform, mistake-free ...
... paper sandwiches are composed of a precut ... thick filter paper that are preassembled into ... These 7 x 8.5 cm membrane sandwiches ... Gel-sized gels and are supplied as a ...
Biology Products: