Navigation Links
Synapses recycle proteins for the release of neurotransmitters
Date:11/10/2010

Neurons communicate via chemical transmitters which they store in the bubble-like synaptic vesicles and release as required. To be able to react reliably to stimulation, neurons must have a certain number of "acutely releasable" vesicles. With the help of a new method, neuroscientists at the Max Planck Institute of Experimental Medicine in Gttingen have now discovered that neurons systematically recycle the protein components necessary for transmitter release and in this way guarantee the reliability of signal transmission in the brain. If this process is disrupted, the communication between the neurons quickly comes to a standstill and vital processes that rely on the rapid transmission of information, for example seeing or the instant identification of a sound source, become impossible to carry out. (Neuron, November 4, 2010)

Neurons transmit signals to each other via specialised contacts known as synapses. When a transmitting neuron is excited, it releases chemical transmitters that are discharged by tiny membrane-enclosed vesicles and then reach the recipient cell. The release of the transmitters is carried out through the fusion of the vesicles with the cell membrane - a process that requires the interaction of different protein components in the cell.

Before the transmitter vesicles can fuse with the neuronal membrane they must first be transformed into an active state. The corresponding biochemical process is referred to as priming. During this process, a structure known as a SNARE complex is constructed from protein components that are required for the rapid fusion of the vesicles with the cell membrane.

Headed by the Korean neuroscientist JeongSeop Rhee, a group of researchers from the Max Planck Institute of Experimental Medicine in Gttingen have now developed a new method that can be used for the direct measurement of synaptic vesicle priming. The scientists made use of a method that, before now, could only be us
'/>"/>

Contact: JeongSeop Rhee
rhee@em.mpg.de
49-551-389-9694
Max-Planck-Gesellschaft
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Sponges recycle carbon to give life to coral reefs
2. A win-win: U-pick pumpkin farms recycle urban leaves
3. Breast cancer cells recycle to escape death by hormonal therapy
4. Chemists concoct new agents to easily study critical cell proteins
5. LSUHSC study IDs proteins regulating water retention in salt-sensitive hypertension
6. New clues to how cancer-related proteins plasmin, thrombin lose inhibition
7. Key difference in how TB bacteria degrade doomed proteins
8. Model unfolds proteins gently
9. Slicing proteins with Occams Razor
10. Scripps Research scientists win $65 million in new grants to reveal form and function of proteins
11. RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Synapses recycle proteins for the release of neurotransmitters
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the ... 2015-2019" report to their offering. ... is the adoption of multimodal biometric systems. Multimodal ... an individual for verification and identification purposes. This ...
(Date:12/11/2014)... Minn. , Dec. 10, 2014  Data ... physiologic monitoring, has released a new series of ... of preclinical toxicology researchers. M series, part of ... toxicologists collect the best possible physiologic data when ... Adding functional endpoints to toxicology studies has ...
(Date:12/10/2014)... 9, 2014  Valencell, a leader in performance biometric ... staggering demand from its licensees for highly accurate, clinically ... not solely coming from fitness and health sectors, but ... "A wearable is only as useful as the biometric ... ultimate driver in long-term mass consumer adoption of wearable ...
Breaking Biology News(10 mins):Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2New telemetry implants expected to change how large animal toxicology studies are conducted 2Wearable Technology Products Demand Highly Accurate Biometric Technology 2
... who carry weight in the thighs and backside have ... blood pressure and heart disease than apple-shaped people who ... nutrition researchers at Washington University School of Medicine in ... In two studies, they report excess liver fat ...
... associated with higher levels of omega-3 fatty acids in plasma ... the European study IMMIDIET that will be published in the ... on, an official publication of the American Society for Nutrition ... The study suggests that wine does better than other alcoholic ...
... men want younger women, often touting their intelligence and ... at Gothenburg University and Oxford University that studied 400 ... choose partners. Research in the theory of evolution ... and women choose their partners. Among the more ...
Cached Biology News:Apple or pear shape is not main culprit to heart woes -- it's liver fat 2A little wine boosts omega-3 in the body: Researchers find a novel mechanism for a healthier heart 2A little wine boosts omega-3 in the body: Researchers find a novel mechanism for a healthier heart 3Myth about 'dirty old men' supported by science 2
(Date:12/24/2014)... 23, 2014 On Friday, December ... 83, the Omnibus and Continuing Resolution Appropriations Act ... hydrocephalus a condition eligible to receive funding through ... by the Department of Defense (DoD). The Hydrocephalus ... on Capitol Hill, is celebrating this victory for ...
(Date:12/24/2014)... report expects global cell isolation and expansion market to ... carefully analyzed data about the vital drivers, restraints, trends, ... Copy of Report @ http://bit.ly/1yUxy0T , According ... will keep witnessing growth at an impressive CAGR during ... by rapid technological advancements, government funding and investments, and ...
(Date:12/24/2014)... LONDON , December 23, 2014 ... Review Algeria , out today and available for free ... the actors driving change and growth in the sector today. ... has scored notable successes has been in developing a homegrown ... 70 percent local production still remains some way off. A ...
(Date:12/22/2014)... PA & Brussels (PRWEB) December 22, 2014 ... (CfPIE), the global leader of technical training across ... Society for Clinical Data Management (SCDM) to provide ... and certification programs —providing access to the more ... partnership extends SCDM members with 10% off when registering ...
Breaking Biology Technology:Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3
... RNAPrep is a SPRI based magnetic bead purification kit for , ... Eukaryotic cultured cells. RNAPrep is a simple and reproducible 3-step , ... applications such as microarray , and RT-PCR gene ... and consistently delivers high yield recovery and purity , ...
... , Although the <A , ... siRNA Labeling Kits were developed for labeling siRNA, they can , ... can be used for this application. See "<A ... Introduced dsRNA in Cells " for experimintal data using dsRNA , ...
... , , NAVIGATE THIS ARTICLE: <A , ... <A , href="#3">RNA , ... Transfer > <A , href="#5">Hybridization, , ... href="#6">Stripping , & Reprobing , , ...
Cached Biology Technology:RNAPrep - Total RNA Isolation Purification 2RNAPrep - Total RNA Isolation Purification 3Fluorescently Labeling Long dsRNA with the Silencer siRNA Labeling Kit 2Fluorescently Labeling Long dsRNA with the Silencer siRNA Labeling Kit 3Fluorescently Labeling Long dsRNA with the Silencer siRNA Labeling Kit 4Northern Analysis: The Basics 2Northern Analysis: The Basics 3Northern Analysis: The Basics 4Northern Analysis: The Basics 5Northern Analysis: The Basics 6Northern Analysis: The Basics 7Northern Analysis: The Basics 8Northern Analysis: The Basics 9Northern Analysis: The Basics 10Northern Analysis: The Basics 11Northern Analysis: The Basics 12Northern Analysis: The Basics 13Northern Analysis: The Basics 14Northern Analysis: The Basics 15Northern Analysis: The Basics 16Northern Analysis: The Basics 17Northern Analysis: The Basics 18Northern Analysis: The Basics 19
Anti-DAP-1, Rabbit Monoclonal Immunogen: KLH-conjugated synthetic peptide corresponding to the C-terminal region of human DAP-1. Molecular Weight: 11 kDa Quality Assurance: Routinely eval...
Anti-Mouse Macrophages (Metallophillic), Purified (Clone MOMA-1) (rat IgG2a)...
Request Info...
Human Osteocalcin (1-22) mature form. Also reacts with Osteocalcin (1-44) and Osteocalcin (1-49). No reactivity with Bone sialoprotein....
Biology Products: