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Sweeping view of prostate cancer genome yields deep insights
Date:2/9/2011

ancer," says Dr. Rubin. "We can also imagine eventually developing more personalized diagnostic tools for patients with recurrent tumors, to essentially follow the tumors' progression by testing for new genomic alterations."

Although the researchers' findings need to be studied further and extended to larger numbers of tumor samples, this initial analysis has opened up many new avenues of investigation, underscoring the power of applying whole genome sequencing to cancer.

"Many of these features were invisible before," says Dr. Garraway. "Now, we're realizing that by sequencing whole genomes in prostate cancer, there's a lot more to see. These discoveries are teaching us a great deal about prostate cancer biology that we simply hadn't appreciated previously."


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Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

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