Navigation Links
Susceptibility genes for cerebral infarction or hemorrhage in the Han in Hunan, China
Date:7/17/2013

Atherosclerosis is widely recognized as an independent risk factor for stroke, and its occurrence is closely related to lipid metabolism. numerous studies using transgenic and knockout animals have shown that scavenger receptor class B type I has a protective effect against atherosclerosis. Previous studies of scavenger receptor class B type I gene polymorphisms have focused on the exon 1 G4A polymorphism and the exon 8 C1050T polymorphism, and these polymorphic loci impact blood lipid levels and are involved in the dyslipidemia in diabetes patients. A recent study published in the Neural Regeneration Research (Vol. 8, No. 16, 2013) entitled "Susceptibility gene for stroke or cerebral infarction in the Han population in Hunan Province of China" has verified that A allele frequency was significantly lower than that in normal controls. The serum level of high-density lipoprotein cholesterol in patients with the scavenger receptor class B type I gene G4A GA + AA genotype was significantly higher, while the serum level of low-density lipoprotein cholesterol was significantly lower than that in patients with the GG genotype, in both the atherosclerotic cerebral infarction and cerebral hemorrhage groups. Authors believe that the G4A polymorphism of the scavenger receptor class B type I gene is a possible predisposing risk factor for atherosclerotic cerebral infarction, and that it has no association with cerebral hemorrhage in the Han population in Hunan province of China. The A allele is possibly associated with the metabolism of high-density and low-density lipoprotein cholesterol.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert

Page: 1

Related biology news :

1. UCI study reveals why Down syndrome boosts susceptibility to other conditions
2. Stress-resilience/susceptibility traced to neurons in reward circuit
3. New research helps predict susceptibility to Burkitt lymphoma
4. Gene variations linked to lung cancer susceptibility in Asian women
5. Mutations in autism susceptibility gene increase risk in boys
6. Exome sequencing of health condition extremes can reveal susceptibility genes
7. A new breast cancer susceptibility gene
8. Cigarette smoke impacts genes linked to health of heart and lungs
9. Insecticide causes changes in honeybee genes, research finds
10. Symptoms of Prader-Willi syndrome associated with interference in circadian, metabolic genes
11. Its all in the genes -- including the tracking device
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/15/2016)... Research and Markets has announced ... 2016-2020,"  report to their offering.  , ... global gait biometrics market is expected to grow ... 2016-2020. Gait analysis generates multiple variables ... to compute factors that are not or cannot ...
(Date:3/29/2016)... , March 29, 2016 LegacyXChange, ... LegacyXChange "LEGX" and SelectaDNA/CSI Protect are pleased to announce ... used in a variety of writing instruments, ensuring athletes ... originally created collectibles from athletes on LegacyXChange will be ... of the DNA. Bill Bollander , ...
(Date:3/18/2016)... , March 18, 2016 ... Suppliers of Biometrics, ICT, Manned & Unmanned Vehicles, Physical infrastructure ... & security companies in the border security market and the ... and Europe has led visiongain ... companies improved success. --> defence & security ...
Breaking Biology News(10 mins):
(Date:5/4/2016)... , ... May 04, 2016 , ... PBI-Gordon Corporation is ... Agricultural Sales. , Doug began his career at PBI-Gordon in February 1988, after ... a wide variety of roles, ranging from customer service to national product manager, to ...
(Date:5/3/2016)... 2016 The report "Biochips ... Gene Expression) Lab-on-a-chip (IVD & POC, Proteomics), ... Centers), Fabrication Technology (Microarrays, Microfluidics) - Forecast ... is expected to reach USD 17.75 Billion ... 2015, growing at a CAGR of 18.4% ...
(Date:5/3/2016)... ... ... In a list published by the Boston Business Journal, iLab Solutions ... percentage of the state's 615,000+ small businesses. The list examined companies based in the ... to 2015. , As this award comes on the heels of iLab’s ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... of Dr. Nancy Gillett to its Board of Directors. Dr. Gillett recently retired ... Corporate Executive Vice President and Chief Scientific Officer. A board-certified veterinary pathologist, Dr. ...
Breaking Biology Technology: