Navigation Links
Surprising discovery: The skin communicates with the liver
Date:12/6/2013

ss could be the reason why the mice accumulated fat in the liver and became weak when weaned from their mother", says Ditte Neess.

To clarify this, the researchers made some mice that lacked the fat binding protein only in the skin. Similar to the full knockouts these mice had difficulties after weaning and accumulated fat in the liver. So this showed that the lack of the fat-binding protein in the skin was sufficient to induce accumulation of fat in the liver.

To get to the bottom of how a defect in the skin "talks" to the liver, the researchers decided to cover the mice with vaseline. This would prevent water evaporating from the skin and thus stopping the heat loss. As a result the fat accumulation in the liver disappeared. But as vaseline contains fat, that could theoretically be absorbed by the skin or ingested by the mice, the researchers were a little unsure if there were side effects from the vaseline. A student proposed to cover the mice with liquid latex, which she found in a local sex shop.

Having covered the mice in blue latex the researchers saw that fat accumulation in the liver again disappeared.

"We believe that the leaking of water from the skin makes the mice feel cold, and that this leads to breaking down of fat in their adipose (fat) tissue. The broken down fat is then moved to the liver. The mice move energy from the tissues to the liver", Susanne Mandrup and Ditte Neess explain.


'/>"/>

Contact: Birgitte Svennevig
birs@sdu.dk
University of Southern Denmark
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Feral cats avoid urban coyotes, are surprisingly healthy
2. Bats and whales behave in surprisingly similar ways
3. Surprising underwater-sounds: Humpback whales also spend their winter in Antarctica
4. Study finds surprising benefits about diary cow inflammation
5. In subglacial lake, surprising life goes on
6. A surprising new function for small RNAs in evolution
7. Surprising findings on hydrogen production in green algae
8. Scientists find surprising new influence on cancer genes
9. Computer modeling reveals how surprisingly potent hepatitis C drug works
10. New look at cell membrane reveals surprising organization
11. Climate changes effects on temperate rain forests surprisingly complex
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Surprising discovery: The skin communicates with the liver
(Date:8/19/2014)... in supermarkets to encourage healthier spending habits? A new ... very question by tracking the purchasing records in a ... rate the nutritional value of foods for sale. , ... Just, PhD, and Brian Wansink PhD, author of Slim ... 150 Hannaford Supermarkets in the Northeastern United States between ...
(Date:8/19/2014)... at retail seafood counters in 10 different states ... consumers to unexpectedly high levels of mercury, a ... a fish of the same species, but from ... offense, according to new research by University of ... seafood is essential to allow consumers to choose ...
(Date:8/19/2014)... seas during warm phases and became extinct during cold ... a link between marine crocodilian diversity and the evolution ... 140 million years. , The research, led by ... and formerly from the University of Bristol, UK is ... crocodiles are ,cold-blooded, animals that mainly live in fresh ...
Breaking Biology News(10 mins):Seafood substitutions can expose consumers to unexpectedly high mercury 2Seafood substitutions can expose consumers to unexpectedly high mercury 3Evolution of marine crocodilians constrained by ocean temperatures 2
... methods and better testing systems are needed to advance ... to a series of review articles in Human ... Ann Liebert, Inc ( www.liebertpub.com ). The articles and ... www.liebertpub.com/hum Prostate cancer is one of the ...
... Oxford, 12 July 2010 - The British Mycological Society, ... technical and medical information, today announced the final programme ... Fungi. This congress takes place every 4 years at ... the Edinburgh International Conference Centre, a comprehensive programme encompasses ...
... with your chip shot? Constant drills with your wedge may ... a new study shows why. Previous studies have shown ... better than practice focused on a single task. Cognitive neuroscientists ... paradox in a new study in Nature Neuroscience . ...
Cached Biology News:Innovation and current status of prostate cancer gene therapy featured in Human Gene Therapy 2The biology of fungi -- 1.5 million species -- 1 congress 2Why (smart) practice makes perfect 2
(Date:8/19/2014)... -- Research and Markets  has announced the addition of the ... report to their offering. This report analyzes ... Thousands by the following Product Segments: Media, Sera, and Reagents. ... Canada , Japan , ... Latin America . Annual estimates and forecasts are provided for ...
(Date:8/19/2014)... Research and Markets  has announced the addition ... Strategic Business Report" report to their offering. ... Fuel Cells (SOFCs) in US$ Thousands. The report provides separate ... Europe , Asia-Pacific , ... for the period 2012 through 2020. Market data and analytics ...
(Date:8/19/2014)... 19, 2014 Research and ... the "Spectroscopy Equipment and Accessories - ... their offering. This report ... and Accessories in US$ Thousands by the ... Raman Spectrometers, NMR-EPR Spectrometers, Near Infrared (NIR) ...
(Date:8/19/2014)...   Synthetic Biologics, Inc. (NYSE MKT: ... and drug programs targeting specific pathogens that cause ... novel C. difficile development program will ... Conference on Antimicrobial Agents and Chemotherapy (ICAAC), September ... Synthetic Biologics, Senior Vice President, Research ...
Breaking Biology Technology:Global Cell and Tissue Culture Supplies - Strategic Business Report 2014 2Global Solid Oxide Fuel Cells (SOFCs) - Strategic Business Report 2014 2Global Spectroscopy Equipment and Accessories - Strategic Business Report 2014 2Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 2Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 3Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 4
... March 11 earthquake and rolling blackouts that are severely ... internship program NanoJapan is scrambling to run its annual ... travel to Japan for lab internships, NanoJapan is offering ... students to Rice University laboratories for three months. ...
... 25, 2011 WaferGen Biosystems, Inc. (OTCBB:WGBS), a ... announced it has entered into definitive agreements with ... Partners, LLC, Deerfield Management and Merlin Nexus, and ... a $30.4 million private placement financing of equity ...
... Texas, May 25, 2011 /PRNewswire/ -- ... company, today announced that the United States Patent and Trademark ... patent entitled "Saposin D and Fam3C are Biomarkers for Alzheimer,s ... Fam3c as well as combinations that include these biomarkers. ...
Cached Biology Technology:Reverse NanoJapan: Rice to host 25-30 Japanese students 2WaferGen Announces $30 Million Financing 2WaferGen Announces $30 Million Financing 3WaferGen Announces $30 Million Financing 4Vermillion Announces Notice of Allowance for Alzheimer Patent 2Vermillion Announces Notice of Allowance for Alzheimer Patent 3
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Request Info...
QML offers standard and customized paraffin embedded tissue blocks....
Request Info...
Biology Products: