Navigation Links
Super-thin membranes clear the way for chip-sized pumps
Date:10/28/2013

The ability to shrink laboratory-scale processes to automated chip-sized systems would revolutionize biotechnology and medicine. For example, inexpensive and highly portable devices that process blood samples to detect biological agents such as anthrax are needed by the U.S. military and for homeland security efforts. One of the challenges of "lab-on-a-chip" technology is the need for miniaturized pumps to move solutions through micro-channels. Electroosmotic pumps (EOPs), devices in which fluids appear to magically move through porous media in the presence of an electric field, are ideal because they can be readily miniaturized. EOPs however, require bulky, external power sources, which defeats the concept of portability. But a super-thin silicon membrane developed at the University of Rochester could now make it possible to drastically shrink the power source, paving the way for diagnostic devices the size of a credit card.

"Up until now, electroosmotic pumps have had to operate at a very high voltageabout 10 kilovolts," said James McGrath, associate professor of biomedical engineering. "Our device works in the range of one-quarter of a volt, which means it can be integrated into devices and powered with small batteries."

McGrath's research paper is being published this week by the journal Proceedings of the National Academy of Sciences.

McGrath and his team use porous nanocrystalline silicon (pnc-Si) membranes that are microscopically thinit takes more than one thousand stacked on top of each other to equal the width of a human hair. And that's what allows for a low-voltage system.

A porous membrane needs to be placed between two electrodes in order to create what's known as electroosmotic flow, which occurs when an electric field interacts with ions on a charged surface, causing fluids to move through channels. The membranes previously used in EOPs have resulted in a significant voltage drop between the elect
'/>"/>

Contact: Peter Iglinski
peter.iglinski@rochester.edu
585-764-7002
University of Rochester
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers capture images of open channel that moves proteins across cell membranes
2. Photosynthesis: Membranes in tight corners
3. Modifications of a nanoparticle can change chemical interactions with cell membranes
4. Patel recognized with NSF Career Award for computer-modeling research on cell membranes
5. Microfluidic platform gives a clear look at a crucial step in cancer metastasis
6. Chair Mats of Glass Company Clearly Innovative Announces the Launch of 20 New Dealers in the Midwest
7. Researchers reveal the clearest new pictures of immune cells
8. Less haze in Singapore as the cause becomes clearer and more complex
9. CNIO researchers identify a new gene that is essential for nuclear reprogramming
10. U-M researchers find new way to clear cholesterol from the blood
11. Invention could make spent nuclear fuel useful for irradiation purposes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Super-thin membranes clear the way for chip-sized pumps
(Date:8/28/2014)... A free mobile app called TX Invasives is now ... The University of Texas at Austin for identifying harmful ... , Invasive species in the United States cause about ... they destroy agricultural crops, clog waterways, kill native plants ... TX Invasives app for reporting where invasive species occur, ...
(Date:8/28/2014)... German . ... to a striking pattern of blue stripes alternating with golden ... cells, and yellow cells emerge during growth in the skin ... mosaic to compose the characteristic colour pattern. ,While ... interact to form proper stripes, the embryonic origin of the ...
(Date:8/28/2014)... 2014) Researchers at the University of Minnesota have ... (FSHD) to be used for muscle regeneration research as ... for FSHD. , The research is published in the ... , There is no treatment for FSHD, which is ... of muscular dystrophy. FSHD is an unusual genetic disorder ...
Breaking Biology News(10 mins):Mobile app makes ID of harmful plants, insects in Texas a snap 2How the zebrafish gets its stripes 2How the zebrafish gets its stripes 3UMN researchers find animal model for understudied type of muscular dystrophy 2
... The tummy,s taste for red wine with red meat , ... happens when red wine meets red meat? If the rendezvous ... bounty of healthful chemical compounds may thwart formation of harmful ... study, which reinforces the benefits of consuming wine and other ...
... closer to understanding the recent demise of billions of honey ... a common bee virus. Deformed wing virus (DWV) is passed ... parasitic mite called Varroa destructor when it feeds. However, research ... General Virology suggests that the virus does not replicate ...
... of Crohn,s disease researchers has combined data from ... variants associated with the inflammatory bowel disorder, bringing ... Several of these are involved with the ... evidence that disruptions in a process called autophagy ...
Cached Biology News:American Chemical Society's Weekly PressPac -- June 25, 2008 2American Chemical Society's Weekly PressPac -- June 25, 2008 3American Chemical Society's Weekly PressPac -- June 25, 2008 4American Chemical Society's Weekly PressPac -- June 25, 2008 5American Chemical Society's Weekly PressPac -- June 25, 2008 6American Chemical Society's Weekly PressPac -- June 25, 2008 7American Chemical Society's Weekly PressPac -- June 25, 2008 8American Chemical Society's Weekly PressPac -- June 25, 2008 9Bee disease a mystery 2International team identifies 21 new genetic risk factors for Crohn's disease 2
(Date:8/29/2014)... one of the most promising technologies for future quantum ... (photons) instead of electrons. First, it is necessary to ... and control their direction. Researchers around the world have ... but now scientists at the Niels Bohr Institute have ... one at a time and in a particular direction. ...
(Date:8/29/2014)... 29, 2014 /PRNewswire/ - iCo Therapeutics ("iCo" or ... financial results for the six months ended June ... in Canadian dollars and presented under International Financial ... Highlights , Announced top-line results related ... endpoint for subjects enrolled in the Phase 2 ...
(Date:8/29/2014)... A major challenge before new biotechnology start-up ... of Boston-Cambridge, is gaining visibility that can lead to ... Director of Boston’s Adult Stem Cell Technology Center, LLC ... of his company an important priority since he started ... a social media marketing campaign launched earlier ...
(Date:8/28/2014)... August 28, 2014 Best Sanitizers, Inc., ... an alcohol-based hand sanitizer, asks food processors and food ... the hand sanitizer they’re currently using to Best Sanitizers’ ... hygiene is critical to fighting cross-contamination and the spread ... Sanitizers believes there are key criteria that make a ...
Breaking Biology Technology:Breakthrough in light sources for new quantum technology 2iCo Therapeutics Announces Second Quarter 2014 Financial Results 2iCo Therapeutics Announces Second Quarter 2014 Financial Results 3iCo Therapeutics Announces Second Quarter 2014 Financial Results 4The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 3
... Funding Milestone Continues Progress at Seneca, Illinois ... ... NBF ) announced today that it has satisfied the conditions ... million,senior secured credit facility with WestLB AG, one of the world,s ...
... Phase 2b Trial Expected to Begin in the ... 4 Mpex Pharmaceuticals, Inc. today,announced that the ... Products Development has granted Mpex orphan drug designation ... pulmonary,infections due to Pseudomonas aeruginosa and other bacteria ...
... the Chinese Pharmaceutical ... CHENGDU, China, March 4 /Xinhua-PRNewswire-FirstCall/ -- Tianyin,Pharmaceutical, ... and,supplier of modernized traditional Chinese medicine ("TCM") based ... members:,Professor Zunjian Zhang, Ph.D., Professor Jianping Hou, Ph.D. ...
Cached Biology Technology:Nova Biosource Fuels Announces First Funding Under $41 Million Senior Secured Credit Facility 2Mpex Candidate, MP-376, Granted U.S. Orphan Drug Status for the Treatment of Cystic Fibrosis 2Mpex Candidate, MP-376, Granted U.S. Orphan Drug Status for the Treatment of Cystic Fibrosis 3Tianyin Pharmaceutical Appoints Three New Independent Board Members 2Tianyin Pharmaceutical Appoints Three New Independent Board Members 3Tianyin Pharmaceutical Appoints Three New Independent Board Members 4
IC50: 35 ng/ml · Limit of detection: 8 ng/ml...
... PGE2-d4 contains 4 deuterium atoms at ... It is intended for use as an ... E2 (PGE2) by GC- or LC-mass spectrometry. ... products of arachidonic acid and one of ...
, Glycerol 30%...
Deletions, insertions or substitutions. Mutations in plasmids of size up to 15 kb. Single or multiple mutations...
Biology Products: