Navigation Links
Super-mini vehicles carry therapeutics and imaging agents into body with mega results
Date:6/7/2011

nanomedicine rely on multiple weak forces, such as those associated with viral capsids and proteins.

Engineered self-assemblies used in nanomedicine come in over five groups of structural shapes, including the micellar nanostructure.

"We have recently developed a novel strategy that utilizes micelles self-assembled from recombinant polypeptides after attaching doxorubicin, a cancer drug, to deliver the drug," explained Dr. Chilkoti, who is also the director of the Duke University Center for Biologically Inspired Materials and Material Systems.

According to Dr. MacKay, a co-corresponding author of the report, the stability of micelles is important to their success or failure as drug delivery systems.

"The stability of micelles has thermodynamic and kinetic components," he said. "All factors that influence micellar stability can be tuned at the genetic level. Thus, we believe that genetically encoded polypeptide micelles are likely to play an increasing role in the design of next generation nanoscale carriers of drug and imaging agents."

In their report, the authors evaluate the structural and physiochemical properties, as well as the potential applications, of each type of structure.


'/>"/>

Contact: Randolph Fillmore
rfillmore@nasw.org
University of South Florida (USF Health)
Source:Eurekalert

Page: 1 2

Related biology news :

1. Healing wounds with lasers, vehicles that drive themselves, other cutting-edge optics
2. Chasing tiny vehicles
3. Ethanol-powered vehicles generate more ozone than gas-powered ones
4. ORNL strengthens DOE-funded clean vehicles team
5. UW leading $7.5 million study of animal flight and aerial vehicles
6. Earthworm activity can alter forests carbon-carrying capabilities
7. Polarized light guides cholera-carrying midges that contaminate water supplies
8. Weizmann Institute scientists show extra copies of a gene carry extra risk
9. Dust deposited in oceans may carry elements toxic to marine algae
10. Gorillas carry malignant malaria parasite, study reports
11. Tool use in an invertebrate: The coconut-carrying octopus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... Antarctic fishes that manufacture their own "antifreeze" ... also suffer an unfortunate side effect, researchers report: ... bodies resist melting even when temperatures warm. ... Proceedings of the National Academy of Sciences . ... undesirable consequence of the evolution of antifreeze proteins ...
(Date:9/22/2014)... in this image burn in Khabarovsk Krai, a territory occupying ... hotspots, accompanied by plumes of smoke mark active fires. The ... east towards the Sea of Okhotsk. Taiga and ... forest inhabit the central depression, and deciduous forests are the ... common in Russia in the summer, the 2014 wildfire season ...
(Date:9/22/2014)... greater risk for stress-related diseases like type 2 ... new study by Brandeis University. , It,s long ... similar to the effects of illness or injury, ... part of our body,s healing response, runaway inflammation ... , In a recently published paper in ...
Breaking Biology News(10 mins):Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 2Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 3Obesity and stress pack a double hit for health 2
... to a friend's house or deciding on a political ... make decisions based on incomplete information and update those ... such sophisticated decision making in the cerebral cortex, which ... and little understood," according to Wako Yoshida and Shin ...
... little plastic model of a molecule he keeps in ... a ball. That's about the shape of a soy ... assistant professor of agricultural and biosystems engineering. Then he ... what happens when researchers add some glycerin ?a byproduct ...
... all have tastes we love, and tastes we hate. And yet, ... as we get older or we get tired of eating the ... study gives new evidence about what's going on in the brain ... something we once hated. , And although the study used ...
Cached Biology News:Where we change our mind 2Iowa State researchers improving plastics made from corn and soy proteins 2Tastes great! Study shows brain's response to pleasing -- and changing -- tastes 2Tastes great! Study shows brain's response to pleasing -- and changing -- tastes 3
(Date:9/22/2014)... University of Minnesota electrical engineering researchers have developed ... time demonstrates mechanical transportation of light. The discovery ... more efficient optical devices for computation and communication. ... electrical and computer engineering assistant professor Mo Li ... published online and will appear in the October ...
(Date:9/22/2014)... Lawrence Livermore National Laboratory Director ... Friday renewed their institutional commitment by signing a ... to expand the collaborative work in the areas ... energy and environmental sciences. , This renewal represents ... in December 2009 and is a framework to ...
(Date:9/22/2014)... YORK , Sept. 22, 2014 US ... US demand for specialty biocides is forecast to rise ... In volume terms, demand is projected to increase 1.3 ... same period. A strong rebound in construction expenditures will ... paint and coatings markets, while growth in consumer spending ...
(Date:9/22/2014)... Jose, California (PRWEB) September 22, 2014 ... Chitin and chitosan are natural biopolymers available in ... extracted from easily available resources such as shells ... and chitosan is mainly due to the high ... cellulose. Chitosan finds application in various industries owing ...
Breaking Biology Technology:Engineers show light can play seesaw at the nanoscale 2Lawrence Livermore Renews Pact with Georgetown University to Expand Research and Education in Science and Policy 2US Biocides Market 2US Biocides Market 3Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 2Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 3
... SAN DIEGO, Oct. 15 PURE Bioscience (Nasdaq:,PURE), ... today reported revenues for the fiscal year ended ... 340% compared with $336,400 in the,prior fiscal year. ... taxes,of $(6,540,300), or $(0.24) per share, compared with ...
... Receptor ... CCR9 for Gastrointestinal Diseases, MOUNTAIN VIEW, Calif., ... initiated a Phase I clinical trial of CCX025,the company,s ... inhibits the chemokine receptor known as CCR9.,Structurally distinct from ...
... Oct. 15 The increased emphasis on,safety by ... medical,product development programs and requires rapid, cost-effective and,resource ... effect constructive change can be found in consulting ... clients from compliance errors,that can lead to adverse ...
Cached Biology Technology:PURE Bioscience Reports Fourth Quarter and Year End Results 2PURE Bioscience Reports Fourth Quarter and Year End Results 3PURE Bioscience Reports Fourth Quarter and Year End Results 4PURE Bioscience Reports Fourth Quarter and Year End Results 5PURE Bioscience Reports Fourth Quarter and Year End Results 6PURE Bioscience Reports Fourth Quarter and Year End Results 7ChemoCentryx Advances Second Orally Available CCR9 Antagonist CCX025 Into Clinical Development 2ChemoCentryx Advances Second Orally Available CCR9 Antagonist CCX025 Into Clinical Development 3ChemoCentryx Advances Second Orally Available CCR9 Antagonist CCX025 Into Clinical Development 4Ground Zero Pharmaceuticals Announces Expansion of Regulatory and Product Development Consulting Services 2Ground Zero Pharmaceuticals Announces Expansion of Regulatory and Product Development Consulting Services 3
FluoSpheres® biotin-labeled microspheres, 0.2 µm, yellow-green fluorescent (505/515) *1% solids*...
GM130 Immunogen: Recombinant purified rat GM130 Family / Subclass 1: Signal Transduction Storage: 4 C...
... Anti-NY-ESO-1, clone E978 ... : NM_001327 Immunogen ... protein Formulation: mouse ascites ... Quality Assurance: routinely evaluated ...
R26.4C...
Biology Products: