Navigation Links
Sunburn alert: UVB does more damage to DNA than UVA
Date:7/1/2008

As bombs burst in air this July 4, chances are that sunburn will be the red glare that most folks see and feel. But unfortunately, even when there is no burn, the effects of the sun's ultraviolet (UV) rays can have deadly consequences. Thanks to a new research study published in the July 2008 issue of The FASEB Journal, scientists now know why one type of UV light (UVB) is more likely to cause skin cancer than the other (UVA). This information should be useful to public health officials and government regulatory agencies in identifying specific criteria for exactly how effective consumer products, like sunscreen, are in preventing skin damage leading to skin cancer. It should also allow scientists to pursue new lines of research and treatment into repairing the damage caused by the sun's rays.

"Our study is novel in that it fills the gaps in knowledge of mechanisms involved in sunlight-associated skin cancers, which cover various aspects of DNA damage and repair and genetic alterations," said Ahmad Besaratinia, PhD, Assistant Research Scientist at City of Hope National Medical Center and first author on the report.

According to researchers from City of Hope National Medical Center in Duarte, California, UVB light is more harmful to our skin because our bodies are less able to repair the DNA damage it causes than the damage caused by UVA light. To reach their conclusions, scientists exposed three sets of cells to UVA light, UVB light and simulated sunlight. Then they compared these cells to an unexposed control group to analyze how well these cells were able to repair the damage. In addition, they analyzed published data on the genetics involved in human skin cancers. The researchers found that cells were more easily able to repair the damage caused by the UVA light, which explains why UVA light has been perceived as "safer" than UVB light. Despite this perception, scientists and public health experts caution that UVA light can and does cause serious damage that can and does lead to skin cancer.

"We know that sunlight causes skin cancer and that breakdown of the ozone layer exposes us to ever more ultraviolet radiation. This work tells us that both forms of UVA and UVB in sunlight cause damage to DNA. It forms a missing link in the chain of events from sun exposure to tumor formation," said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal. "This research article gives us information that could lead to better sunscreens or effective 'after sun' products. It promises new ways to prevent - and perhaps to treat - the epidemic of skin cancer brought on by modern life."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related biology news :

1. Hypertension treatment effective in reversing vascular damage
2. QUT researchers develop smart instrument for tissue damage assessment
3. Researchers reveal structure of protein that repairs damage to cancer cells
4. Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
5. New mineralogical techniques contribute to prevent national heritage damage
6. Blueberry and green tea containing supplement protects against stroke damage
7. Will global warming increase plant frost damage?
8. Carbon monoxide may cause long-lasting heart damage
9. Why diving marine mammals resist brain damage from low oxygen
10. An ambulance man for muscle damage
11. Club drugs inflict damage similar to traumatic brain injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... Research and Markets has announced the addition of the "Global ... 2025" report to their offering. ... The Global Vehicle Anti-Theft System Market is ... next decade to reach approximately $14.21 billion by 2025. ... all the given segments on global as well as regional levels ...
(Date:3/20/2017)... At this year,s CeBIT Chancellor Dr. Angela ... The Chancellor came to the DERMALOG stand together with the Japanese Prime ... partner country. At the largest German biometrics company the two government leaders ... iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
(Date:3/9/2017)... , Australia , March 9, ... study data at the prestigious World Lung Imaging Workshop ... Andreas Fouras , was invited to deliver the ... pulmonary medicine. This globally recognised event brings together leaders ... share the latest developments in lung imaging. ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... , March 23, 2017  Northwest Biotherapeutics (OTCQB: ... personalized immune therapies for solid tumor cancers, today ... million financing it announced last Friday, March 17, ... several institutional investors securities totaling 28,843,692 shares, comprised ... and 10,000,000 shares of Class C Warrants pre-funded ...
(Date:3/23/2017)... 2017 Kineta, Inc., a biotechnology company ... in immuno-oncology, today announced the discovery and characterization ... that activate interferon response factor 3 (IRF3) via ... tumor regression in a murine colon carcinoma mouse ... complete tumor regression to initial drug treatment were ...
(Date:3/23/2017)... New Orleans, La. (PRWEB) , ... March 23, ... ... of real-time, industrial monitoring solutions, today announced the hire of Dr. Sigmund “Sig” ... for APMT customer applications, strategic partnerships and joint development activities. , “Dr. Floyd’s ...
(Date:3/22/2017)... Good Start Genetics, a leading family genomics ... million covered lives mark through its most recent payor ... . With newly signed contracts nationally and others ... payor acceptance based on the quality of its science, ... its industry-leading customer care and support and its published ...
Breaking Biology Technology: