Navigation Links
Sugary band-aid may help heal post-operative tissue
Date:5/31/2010

wn, or metabolized, and then safely removed by the body."

Dr. Putnam's lab and his collaborators work to create safe, synthetic compounds from chemicals found in nature. DHA is an intermediary compound produced during the metabolism of glucose, a sugar used by the body for fuel.

To create the new compound, MPEG-pDHA, Dr. Putnam and his lab first bound the single molecule monomer of DHA, which is highly reactive, to a protecting group molecule, making it stable enough to manipulate. This allowed the engineers to bind the monomers together to form a polymer, or chain of molecules, along with MPEG. Doing so allows the polymer gel to be injected through a syringe.

"Making a polymer from DHA has eluded chemical engineers for about 20 years," says Dr. Putnam.

Now in gel form, the compound has the ability to stick tissues together, preventing the pocket from filling with seroma fluid, like an internal Band-Aid, explains Dr. Putnam. The researchers found that the gel prevented or significantly lowered seroma formation or fluid buildup in rats that had breast tissue removed.

"The next step would be to test the gel on larger animals and then in clinical trials in human surgical cases," says Dr. Spector.

Previous results, published by Drs. Putnam and Spector, in the August 2009 issue of the Journal of Biomedical Materials Research, showed that the gel also prevented bleeding in a rat liver.

"This is another aspect of the compound that would be greatly beneficial if proven to be applicable in humans," says Dr. Spector. "The gel could speed the healing and decrease bleeding within the body."


'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2

Related biology news :

1. Sugary cola drinks linked for first time to higher risk of gestational diabetes
2. Genetic variation linked to sugary food
3. Sugary drinks, not fruit juice, may be linked to insulin
4. Reprogram stem cells with heart tissue, which might improve treatments for heart disease
5. Body builders -- the worms that point the way to understanding tissue regeneration
6. Scientists create artificial human skin with biomechanical properties using tissue engineering
7. Obesity gene, carried by more than a third of the US population, leads to brain tissue loss
8. Smart orthopedic implants and self-fitting tissue scaffolding created by UMMS researchers
9. Tissue engineering, imaging neuronal circuits featured in Cold Spring Harbor Protocols
10. NYSCF fellow lead author on study that derives floor plate tissue from embryonic stem cells
11. Brain tumors: Tissue stem cell turning into tumor stem cell
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... LAKE FOREST, Calif. , March 3, ... ("Company"), the leading provider of advanced cryogenic ... serving markets including immunotherapies, stem cells, cell ... health, and reproductive medicine, today announced the ... Hutchinson Cancer Research Centers, ("Fred Hutch") ...
(Date:2/25/2015)... LITTLE ROCK, Ark. , Feb. 25, 2015 ... of software and billing in the Health and ... software as well as to MYiCLUBonline.  The latest ... MYiCLUBonline and the inclusion of cardless check-in via ... demonstrated for the first time through interactive displays ...
(Date:2/23/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ... authentication company focused on the growing mobile commerce market, ... for DISTRIBUTED VOICE DIRECTED PAYMENT METHOD AND ... new groundbreaking payment method. Payment accounts may be selected ... be accessed if both the speech (the word associated ...
Breaking Biology News(10 mins):Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 2Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 3ABC Financial Unveils New Software Enhancements 2ABC Financial Unveils New Software Enhancements 3NXT-ID Patents Voice Directed Payments 2NXT-ID Patents Voice Directed Payments 3
... are essential in the fight against breast cancer. ... system for investigation of physiological and pathological processes ... that occurs during puberty and the alveogenesis processes ... in many tissues during embryogenesis and are also ...
... in a wide variety of cells and tissues, including ... can enter the cytoplasm from the extracellular environment or ... enzymes, other signaling molecules, transcription factors, and cytoskeletal components. ... "Calcium Signaling" explores the channels and pumps that transport ...
... For one species of seabird in the Galpagos, the child abuse ... The new study of Nazca boobies by Wake Forest University ... who are abused when they are young often grow up to ... the ornithology journal, The Auk . "We were ...
Cached Biology News:Child abuse in birds: Study documents 'cycle of violence' in nature 2
(Date:3/5/2015)... Bi-Biomics today announced a discovery ... additive. The improvement in histological quality provided the ... in all daughter cells. , After processing with ... analyzed at 1000-1600x using light microscopy. Phylogenetic ... all daughter cells displayed predominant binary features --- ...
(Date:3/5/2015)... and TORONTO , March 5, ... a clinical-stage company developing new therapeutics and molecular diagnostics ... that William G. Rice , Ph.D., Chairman, President ... 27th Annual ROTH Conference on Tuesday, March 10 th ... Carlton, Laguna Niguel, CA. Dr. ...
(Date:3/5/2015)... DUBLIN , Mar. 05, 2015 Research and ... addition of the "Mature Biotech Outlook 2015: New ... to their offering. All biotech companies ... Celgene (CELG), in past year, have given a positive ... These companies have been able to select therapy/niche indication ...
(Date:3/5/2015)... e2b teknologies , a premier Sage ... Ohio, today announced a leading independent multi-specialty physician group ... to the latest version of Sage 100 ERP ... its kind in the region, the organization has an ... efficiency and data accessibility are paramount to their ongoing ...
Breaking Biology Technology:Aptose Biosciences to Present at the 27th Annual ROTH Conference 2Aptose Biosciences to Present at the 27th Annual ROTH Conference 3Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 2Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 3Physician Group Practice Chooses e2b teknologies to Support Its Upgrade to Sage 100 ERP 2014 2
... Md., Feb. 15, 2011 United Therapeutics Corporation (Nasdaq: ... for the fourth quarter and year ended December 31, 2010. ... by the growth in our revenues," remarked Martine Rothblatt, ... addition, we are pleased to announce that we expect ...
... Reportlinker.com announces that a new market research report ... Pipeline Insight: Cancer Overview- Breast and Gynecological Cancers ... http://www.reportlinker.com/p0386436/Pipeline-Insight-Cancer-Overview--Breast-and-Gynecological-Cancers---Promising-agents-emerge-for-BRCA-positive-patients.html ... types covered in this report are set to ...
... is available in French . Scientists have ... two paintings by Vincent van Gogh and other artists of ... to understanding how to stop the bright yellow colours of ... brown shade, and fading over time. In the meantime, the ...
Cached Biology Technology:United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 2United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 3United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 4United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 5United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 6United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 7United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 8United Therapeutics Corporation Reports 2010 Fourth Quarter and Annual Financial Results 9Reportlinker Adds Pipeline Insight: Cancer Overview- Breast and Gynecological Cancers - Promising agents emerge for BRCA positive patients 2X-rays show why van Gogh paintings lose their shine 2X-rays show why van Gogh paintings lose their shine 3X-rays show why van Gogh paintings lose their shine 4
The Lambda Control Kit contains lambda DNA and two 25mer primers, which can be used to amplify a 500bp fragment. The lambda DNA is purified by CsCl gradient centrifugation and organic extraction foll...
... Klein Taq is a derivative of Taq ... truncated Thermus aquaticus DNA polymerase. Expressed from ... initiates at Met236, bypassing the 5'-3' exonuclease ... enzyme reveals a highly active and even ...
Homo sapiens similar to Cytosolic acyl coenzyme A thioester hydrolase Antigen: Peptide...
96 Well Base Plate...
Biology Products: