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Sugarcoating fruit fly development
Date:5/29/2009

fied with the sugar tag by Ogt and might be the link between Ogt and development. Further investigations are necessary to find out how the sugar tag affects the function of Polyhomeotic.

"Our findings were very surprising. GlcNAc has been found on so many different proteins in mammalian cells that we expected many processes to go wrong in a fly lacking Ogt. Instead we see a very specific effect on development in fruit flies that is likely brought about by a single nuclear protein that needs the sugar tag to function properly," says Maria Cristina Gambetta, who carried out the research in Mller's lab.


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Contact: Anna-Lynn Wegener
wegener@embl.de
0049-622-138-7452
European Molecular Biology Laboratory
Source:Eurekalert

Page: 1 2

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