Navigation Links
Sugar intake is not directly related to liver disease
Date:11/1/2013

Despite current beliefs, sugar intake is not directly associated with nonalcoholic fatty liver disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Rather, high-calorie diets promote the progression of this serious form of liver disease.

Researchers conducted a double-blind study of healthy, but centrally overweight men to compare the effects of high intakes of two types of sugar, glucose and fructose, in two conditions weight-maintaining (moderate-calorie diet) and weight-gaining (high-calorie diet). In the weight-maintaining period, men on neither diet developed any significant changes to the liver. However, in the weight-gaining period, both diets produced equivalent features of nonalcoholic fatty liver disease, including steatosis (fatty liver) and elevated serum transaminase and triglycerides. These findings indicate that fructose and glucose have comparable effects on one's liver, and calorie intake is the factor responsible for the progression of liver disease.

"Based on the results of our study, recommending a low-fructose or low-glycemic diet to prevent nonalcoholic fatty liver disease is unjustified," said Professor Ian A. Macdonald, study author and faculty of medicine and health sciences, University of Nottingham, UK. "The best advice to give a patient is to maintain a healthy lifestyle with diet and exercise. Our study serves as a warning that even short changes in lifestyle can have profound impacts on your liver."

During the period of increased calorie intake, all study participants experienced significant increases in body weight, waist circumference and total body fat, as expected. Interestingly, satiety was unaltered in spite of weight gain during the high-calorie diet; this reinforces the notion of "hidden calories" in drinks since participants consumed a portion of their calories in liquid form.

Fructose is a simple sugar commonly found in fruits and vegetables. Glucose, also known as grape or blood sugar, is present in all major carbohydrates, such as starch and table sugar.

Nonalcoholic fatty liver disease, the most prevalent liver problem in the U.S. and most Western countries, is the buildup of extra fat in liver cells that is not caused by alcohol. For more on how a low-calorie diet is the best prescription for this form of liver disease, read the article "NAFLD Treatment: Is there More to Talk About Other than Diet and Exercise?" from the October/November issue of AGA Perspectives, the AGA Institute's most prominent non-scientific publication.


'/>"/>

Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related biology news :

1. Measuring blood sugar with light
2. UCLA engineers develop new metabolic pathway to more efficiently convert sugars into biofuels
3. Specific sugar molecule causes growth of cancer cells
4. For disappointed sports fans, defeats increase consumption of fat and sugar
5. Peoples diets show a sugar-fat seesaw
6. Lift weights to lower blood sugar? White muscle helps keep blood glucose levels under control
7. Kids consumption of sugared beverages linked to higher caloric intake of food
8. Organic tomatoes accumulate more vitamin C, sugars than conventionally grown fruit
9. New study finds neither HFCS nor table sugar increases liver fat under real world conditions
10. Boosting galactan sugars could boost biofuel production
11. RIT scientists decode 3 bacterial strains common to grapevines and sugarcane
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2017)... , June 30, 2017 Today, ... developer and supplier of face and eye tracking ... Featured Product provider program. "Artificial ... innovative way to monitor a driver,s attentiveness levels ... from being able to detect fatigue and prevent ...
(Date:5/23/2017)... , May 23, 2017  Hunova, the first robotic gym for ... has been officially launched in Genoa, Italy . The ... and the USA . The technology was ... the market by the IIT spin-off Movendo Technology thanks to a 10 ... Multimedia News Release, please click: ...
(Date:5/6/2017)... RAM Group , Singaporean based ... in biometric authentication based on a novel  ... to perform biometric authentication. These new sensors are based on ... Ram Group and its partners. This sensor will have ... and security. Ram Group is a next generation ...
Breaking Biology News(10 mins):
(Date:7/26/2017)... ... July 25, 2017 , ... ... will garner a better understanding of the considerations needed for designing ideal guide ... The use of CRISPR-Cas9 to create targeted double-strand breaks in genomic DNA has ...
(Date:7/26/2017)... ... July 26, 2017 , ... NLP Logix ... years of diagnostic excellence by Mayo Clinic and the experience in developing and ... be distributed through the Microsoft Azure platform and will focus on assisting physicians ...
(Date:7/26/2017)... N.J. , July 26, 2017  Nurse practitioners play ... to the findings of a Merck Manuals survey ... recent medical conference, revealed that most (88 percent) believe they ... diagnoses, treatments and prescriptions. ... Merck Manuals survey of 210 ...
(Date:7/25/2017)... ... July 25, 2017 , ... Bactana Animal ... efficiency of livestock farming while reducing the use of antibiotics and hormones in ... from Cornell University. , These new proprietary technologies expand the breadth of ...
Breaking Biology Technology: