Navigation Links
Sugar intake is not directly related to liver disease
Date:11/1/2013

Despite current beliefs, sugar intake is not directly associated with nonalcoholic fatty liver disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Rather, high-calorie diets promote the progression of this serious form of liver disease.

Researchers conducted a double-blind study of healthy, but centrally overweight men to compare the effects of high intakes of two types of sugar, glucose and fructose, in two conditions weight-maintaining (moderate-calorie diet) and weight-gaining (high-calorie diet). In the weight-maintaining period, men on neither diet developed any significant changes to the liver. However, in the weight-gaining period, both diets produced equivalent features of nonalcoholic fatty liver disease, including steatosis (fatty liver) and elevated serum transaminase and triglycerides. These findings indicate that fructose and glucose have comparable effects on one's liver, and calorie intake is the factor responsible for the progression of liver disease.

"Based on the results of our study, recommending a low-fructose or low-glycemic diet to prevent nonalcoholic fatty liver disease is unjustified," said Professor Ian A. Macdonald, study author and faculty of medicine and health sciences, University of Nottingham, UK. "The best advice to give a patient is to maintain a healthy lifestyle with diet and exercise. Our study serves as a warning that even short changes in lifestyle can have profound impacts on your liver."

During the period of increased calorie intake, all study participants experienced significant increases in body weight, waist circumference and total body fat, as expected. Interestingly, satiety was unaltered in spite of weight gain during the high-calorie diet; this reinforces the notion of "hidden calories" in drinks since participants consumed a portion of their calories in liquid form.

Fructose is a simple sugar commonly found in fruits and vegetables. Glucose, also known as grape or blood sugar, is present in all major carbohydrates, such as starch and table sugar.

Nonalcoholic fatty liver disease, the most prevalent liver problem in the U.S. and most Western countries, is the buildup of extra fat in liver cells that is not caused by alcohol. For more on how a low-calorie diet is the best prescription for this form of liver disease, read the article "NAFLD Treatment: Is there More to Talk About Other than Diet and Exercise?" from the October/November issue of AGA Perspectives, the AGA Institute's most prominent non-scientific publication.


'/>"/>

Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related biology news :

1. Measuring blood sugar with light
2. UCLA engineers develop new metabolic pathway to more efficiently convert sugars into biofuels
3. Specific sugar molecule causes growth of cancer cells
4. For disappointed sports fans, defeats increase consumption of fat and sugar
5. Peoples diets show a sugar-fat seesaw
6. Lift weights to lower blood sugar? White muscle helps keep blood glucose levels under control
7. Kids consumption of sugared beverages linked to higher caloric intake of food
8. Organic tomatoes accumulate more vitamin C, sugars than conventionally grown fruit
9. New study finds neither HFCS nor table sugar increases liver fat under real world conditions
10. Boosting galactan sugars could boost biofuel production
11. RIT scientists decode 3 bacterial strains common to grapevines and sugarcane
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
(Date:4/14/2016)... Israel , April 14, 2016 ... Authentication and Malware Detection, today announced the appointment of ... assumed the new role. Goldwerger,s leadership appointment ... on the heels of the deployment of its platform ... BioCatch,s behavioral biometric technology, which discerns unique cognitive and ...
(Date:3/29/2016)... , March 29, 2016 ... "Company") LegacyXChange "LEGX" and SelectaDNA/CSI Protect are pleased to ... ink used in a variety of writing instruments, ensuring ... of originally created collectibles from athletes on LegacyXChange will ... analysis of the DNA. Bill Bollander ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
(Date:6/23/2016)... CA (PRWEB) , ... June 23, 2016 , ... ... software, is exhibiting at the Pennsylvania Convention Center and will showcase its product’s ... conference. ClinCapture will also be presenting a scientific poster on Disrupting Clinical Trials ...
(Date:6/23/2016)... June 22, 2016  Amgen (NASDAQ: AMGN ... QB3@953 life sciences incubator to accelerate the ... shared laboratory space at QB3@953 was created to help ... obstacle for many early stage organizations - access to ... sponsorship, Amgen launched two "Amgen Golden Ticket" awards, providing ...
(Date:6/22/2016)... , June 22, 2016 Research and ... Global Markets" report to their offering. ... billion in 2014 from $29.3 billion in 2013. The market is ... of 13.8% from 2015 to 2020, increasing from $50.6 billion in ... projected product forecasts during the forecast period (2015 to 2020) are ...
Breaking Biology Technology: