Navigation Links
Sugar helping map new ground against deadly bug
Date:4/18/2011

A potential vaccine against bacteria that cause serious gastric disorders including stomach cancer may be a step closer following a pioneering study by a University of Guelph chemist.

In the first published study of its kind, a team led by Prof. Mario Monteiro, Department of Chemistry, found a carbohydrate-based antigen caused mice to develop antibodies against a common bacterium linked to gastric cancer.

"This is the first jab at a sugar-based vaccine against Helicobacter pylori," said Monteiro, who completed the study with former undergrad student Stacey Britton.

Their study was published recently in the journal Vaccine.

H. pylori is among numerous risk factors for stomach cancer. About half of the world's population has been infected by the bacterium during their lifetime. In Canada, the bug is especially prevalent in Aboriginal communities. It can cause gastritis and ulcers. Most infections are handled by antibiotics, but a vaccine would improve current treatment, said Monteiro.

Many scientists study potential vaccines based on proteins to prevent or control infection. Since arriving at Guelph in 2004, Monteiro has studied more complicated conjugates containing both proteins and sugars.

The Guelph researchers used a single bacterial strain in mice to induce an immune response against various strains of the bacteria.

He has studied sugar-based vaccines against two other gastric pathogens: Campylobacter jejuni, which causes travellers' diarrhea, and C. difficile, which causes antibiotic-associated diarrhea. He plans to begin studies of conjugates for use against tuberculosis.


'/>"/>

Contact: Mario Monteiro
monteiro@uoguelph.ca
519-824-4120 x53447
University of Guelph
Source:Eurekalert

Page: 1

Related biology news :

1. Sugarcane cools climate
2. Sugarcane bioethanol: Environmental implications
3. Missing sugar molecule raises diabetes risk in humans
4. Living in the matrix: Sugar residues regulate growth and survival of nerve cells
5. Coffee, energy drinkers beware: Many mega-sized drinks loaded with sugar, MU nutrition expert says
6. Shotgun method allows scientists to dissect cells sugar coatings
7. Researchers find link between sugar, diabetes and aggression
8. Scientists discover new mechanism for controlling blood sugar level
9. HIV drugs interfere with blood sugar, lead to insulin resistance
10. Sugar and slice make graphene real nice
11. Research shows sugary drinks do not cause weight gain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)... 2015   Guidepoint , a leading global research ... Pain Management TRACKER, part of the Guidepoint TRACKER ... the medical device and therapeutics markets. The Post-Surgical Pain ... volumes, market share, and adoption rates across three major ... surgery. The Post-Surgical Pain Management TRACKER will ...
(Date:3/26/2015)... , March 26, 2015 ... family, social, recreation and athletic club, today announced it ... to allow freedom of movement for members and staff, ... "Following a comprehensive process, we selected FST,s IMID Access ... and convenience for our members and staff, in addition ...
(Date:3/24/2015)... ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ) has announced the addition of the ... report to their offering. This report analyzes the worldwide ... following Segments: Face Biometrics, and Voice Biometrics. The report provides separate ... Japan , Europe , ... Africa , and Latin America . ...
Breaking Biology News(10 mins):Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6
... by a particular enzyme to modify bacterial chromosome chemistry, ... new kind of drug that could stop virulent bacterial ... in the May 6 issue of the journal Cell. ... enzyme called Dam (DNA adenine methyltransferase) plays a role ...
... that can survive encounters with specific immune system cells ... cells, known as neutrophils, dictate whether our immune system ... the research was released today online in The Journal ... Laboratories (RML), part of the National Institute of Allergy ...
... the field of human embryonic stem cell research receives ... also exploring the potential of adult stem cells for ... adult stem cell research isn't fraught with the controversies ... extremely difficult to isolate and then to multiply in ...
Cached Biology News:Scientists take aim at virulent bacteria by decoding machinery of key control enzyme 2Scientists reveal how disease bacterium survives inside immune system cell 2Scientists reveal how disease bacterium survives inside immune system cell 3Researchers discover mechanism for multiplying adult stem cells 2
(Date:4/28/2015)... 2015  Adaptive Biotechnologies today announced the recent ... The University of Texas MD Anderson Cancer Center ... identification and quantification of populations of B cells ... of people with classical Hodgkin,s lymphoma (CHL). The ... Haematology , represent a first step toward developing ...
(Date:4/28/2015)... ANN ARBOR, Mich. , April 28, 2015 ... OncoTargets and Therapy today shows that the Paradigm ... FoundationOne test across a number of key clinical variables, ... The purpose of the analysis was to ... for profiling cancer patients compared with each other.  ...
(Date:4/28/2015)... (PRWEB) April 28, 2015 More than ... psychosis at some point over the course of their ... symptoms that worsen as the disease progresses. ReachMD ... announces the launch of a series dedicated to PD ... in PD, movement disorders, and psychiatric conditions. , The ...
(Date:4/28/2015)... York, New York (PRWEB) April 28, 2015 ... operations including sales, marketing, and customer service operations across ... The Eeva Test , the first and only FDA-cleared ... proprietary algorithm to aid in embryo selection during IVF. ... career in the field of Reproductive Sciences, including both ...
Breaking Biology Technology:Adaptive Biotechnologies and Researchers from MD Anderson Cancer Center Demonstrate Ability to Detect Hodgkin's Lymphoma in Blood 2Adaptive Biotechnologies and Researchers from MD Anderson Cancer Center Demonstrate Ability to Detect Hodgkin's Lymphoma in Blood 3Paradigm Cancer Diagnostic Test (PCDx) Performed Better Than FoundationOne In Side by Side Clinical Study 2Paradigm Cancer Diagnostic Test (PCDx) Performed Better Than FoundationOne In Side by Side Clinical Study 3ReachMD Launches Series Focusing on Parkinson’s Disease Psychosis 2Progyny Appoints Gary Harton as Group Senior Vice President, Commercial Development 2
... Continues to ... Broaden Product Portfolio, WAYNE, Pa., Feb. 14 ... fiscal second quarter and,six months ended December 31, 2007., For ... the Company,s Drew, Vascular and Escalon Digital Solutions (EMI),business units, which ...
... PALO ALTO, Calif., Feb. 14 CV Therapeutics,Inc. ... accordance with Nasdaq,marketplace rule 4350, the Company issued ... due to additional hiring, primarily in,connection with its ... inducement stock options cover an aggregate 119,200 shares ...
... WASHINGTON, Feb. 14 As part of ... create a pathway for,FDA approval of safe and ... features a footprint in the snow stating: "Don,t ... highlights how meaningful biogenerics legislation should be,balanced to ...
Cached Biology Technology:Escalon(R) Reports Second Quarter Fiscal 2008 Results 2Escalon(R) Reports Second Quarter Fiscal 2008 Results 3Escalon(R) Reports Second Quarter Fiscal 2008 Results 4Escalon(R) Reports Second Quarter Fiscal 2008 Results 5Escalon(R) Reports Second Quarter Fiscal 2008 Results 6Escalon(R) Reports Second Quarter Fiscal 2008 Results 7Escalon(R) Reports Second Quarter Fiscal 2008 Results 8CV Therapeutics Reports Option Grants Under Nasdaq Marketplace Rule 4350 2
Request Info...
Secure-Seal™ spacer, one well, 20 mm diameter, 0.12 mm deep *set of 100*...
Synphilin 1 Immunogen: Synthetic peptide corresponding to residues S(829) L E L N G E K D K D K G R T L Q R T(847) of human Synphilin 1. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Request Info...
Biology Products: