Navigation Links
Sudden cardiac death without recognizable cause
Date:1/29/2009

In about 10% of cases, sudden cardiac death (SCD) in young people is due to a cardiac gene defect. This was the conclusion drawn by Silke Kauferstein of the Department of Forensic Medicine of the Johann Wolfgang Goethe University, Frankfurt, and her coauthors in the current Deutsches rzteblatt International (Dtsch Arztebl Int 2009; 106(4): 41-7).

Sudden cardiac death is defined as unexpected death occurring rapidlyusually within 1 h of the onset of symptomsin persons who had previously seemed to be healthy. It is one of the most frequent causes of death in Europe. Each year, about 100 000 people die of sudden cardiac death in Germany alone. Although SCD mostly affects older people, 5% to 15% of cases are in young people who had previously been asymptomatic.

Most cases of sudden cardiac death can be explained by cardiovascular changes. However, in 10% to 30% of cases, no cause of death can be established, even after a postmortem. Genetically linked diseases of cardiac ion channels are responsible for at least a third of these deaths. As the ion channels are involved in stimulation and conduction in the heart, malfunction can cause cardiac arrythmias, which may lead to ventricular fibrillation.

These primary electrical heart disorders are mostly subject to autosomal dominant inheritance. This means that family members have a 50% risk of being carriers of the modified gene causing the disorder. A genetic study of the affected family is therefore essential if further cases of sudden cardiac death are to be prevented.


'/>"/>

Contact: Elke Bartholomus, MA
bartholomaeus@aerzteblatt.de
Deutsches Aerzteblatt International
Source:Eurekalert

Page: 1

Related biology news :

1. Sudden ecosystem flips imperil worlds poorest regions, say water experts
2. Sudden Oak Death pathogen is evolving, says new study that reconstructs the epidemic
3. Drops in blood oxygen levels may be key to sudden death in some epilepsy patients
4. University of Pittsburgh cardiologists identify new cardiac arrest gene
5. Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery
6. Implanting embryonic cardiac cells prevents arrhythmias
7. CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
8. A home early warning system for cardiac patients
9. Cardiac cell transplant studies show promise in cardiac tissue repair
10. Syntermed licenses Emory ERTb software for enhanced cardiac imaging
11. New mechanism for cardiac arrhythmia discovered
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... No two people are believed to ... York University Tandon School of Engineering and Michigan ... partial similarities between prints are common enough that ... and other electronic devices can be more vulnerable ... in the fact that fingerprint-based authentication systems feature ...
(Date:4/5/2017)...  The Allen Institute for Cell Science today announces ... portal and dynamic digital window into the human cell. ... application of deep learning to create predictive models of ... a growing suite of powerful tools. The Allen Cell ... publicly available resources created and shared by the Allen ...
(Date:4/4/2017)... 4, 2017   EyeLock LLC , a leader ... United States Patent and Trademark Office (USPTO) has issued ... linking of an iris image with a face image ... the company,s 45 th issued patent. ... timely given the multi-modal biometric capabilities that have recently ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... PA (PRWEB) , ... August 15, 2017 , ... ... one of the largest Asian exhibitions for analytical and scientific instruments. This year’s ... will be “New Approaches in Mass Spectrometry for Bioanalytical Applications.” This dynamic presentation ...
(Date:8/15/2017)... ... August 15, 2017 , ... Coffea arabica accounts for 70 ... factors. During this educational webinar, participants will learn about the importance of genomics ... better understanding of how genomics is important for coffee breeding improvement. , Attendees ...
(Date:8/14/2017)... ... August 14, 2017 , ... The Conference Forum ... which will take place on September 6, 2017 at the Marriott Copley Place in ... of Experimental Medicine, Informatics, and Regulatory Strategy, Pfizer Innovative Research Lab, Pfizer, who leads ...
(Date:8/11/2017)... ... August 11, 2017 , ... “There ... particular, more natural alternatives to synthetic ingredients,” said Matt Hundt, President of Third ... the established manufacturing presence and know-how of Biorigin will allow us to bring ...
Breaking Biology Technology: