Navigation Links
Succimer found ineffective for removing mercury
Date:10/22/2010

Succimer, a drug used for treating lead poisoning, does not effectively remove mercury from the body, according to research supported by the National Institutes of Health. Some families have turned to succimer as an alternative therapy for treating autism.

"Succimer is effective for treating children with lead poisoning, but it does not work very well for mercury," said Walter Rogan, M.D., head of the Pediatric Epidemiology Group at the National Institute of Environmental Health Sciences (NIEHS), part of NIH, and an author on the paper that appears online in the Journal of Pediatrics.

"Although it is not approved by the Food and Drug Administration to reduce mercury, succimer is reportedly being used for conditions like autism, in the belief that these conditions are caused, in part, by mercury poisoning," Rogan stated. "Our new data offers little support for this practice."

Although researchers found that succimer lowered blood concentrations of mercury after one week, continued therapy for five months only slowed the rate at which the children accumulated mercury. The safety of higher doses and longer courses of treatment has not been studied.

Most mercury exposure in the United States is from methylmercury, found in foods such as certain fish. Thimerosal, a preservative that was once more commonly used in vaccines, contains another form of mercury, called ethylmercury.

To conduct the study, the researchers used samples and data from an earlier clinical trial, led by NIEHS, called the Treatment of Lead-exposed Children (TLC) trial. In the TLC study, succimer lowered blood lead in 2-year-old children with moderate to high blood lead concentrations.

Using blood samples from 767 children who participated in the TLC trial, the researchers measured mercury concentration in the toddlers' blood samples collected before treatment began, one week after beginning treatment with succimer or placebo, and t
'/>"/>

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Entomological Foundation names 2010 award winners
2. Genetic defect found to cause severe epilepsy and mental retardation
3. Clue to unusual drug-resistant breast cancers found
4. Brain changes found in football players thought to be concussion-free
5. Oldest evidence of dinosaurs found in Polish footprints
6. Robert Edwards, a founder of ESHRE, honored as Nobel laureate
7. Elasticity found to stretch stem cell growth to higher levels
8. Language delays found in siblings of children with autism
9. American Migraine Foundation launches new podcast series
10. New therapy found for lung and skin cancer, based on suicide gene E
11. UofL researcher receives grant from the National Science Foundation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... German . ... risky situations such as exposure to predators. Researchers from ... a long-term study on different populations of great tits ... ambient temperature. High metabolic rates and low temperatures were ... birds were more likely to approach potential predators. , ...
(Date:9/30/2014)... of perilous threats in today,s ocean. From overfishing ... fragile coral ecosystems are disappearing at unprecedented rates ... of corals surrounding the island of Moorea in ... tropical environment: coral guard-crabs. New research from the ... scientist Seabird McKeon and the museum,s predoctoral fellow ...
(Date:9/30/2014)... 30, 2014 Winners of The Economist,s prestigious ... scheduled to take place at the JW Marriott Hong Kong on ... winners will share their experiences and the lessons those hold for ... proven innovation over the past decade, will be presented at a ... the summit. It will be the first time the ceremony has ...
Breaking Biology News(10 mins):Risky metabolism 2Smithsonian scientists discover coral's best defender against an army of sea stars 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7
... plants battle for space, often the actual battle is for ... Nebraska-Lincoln gives important new information on how plants can change ... species to invade and take over native plants. In ... Proceedings of the National Academy of Sciences , UNL biologist ...
... LAFAYETTE, Ind. - Catching adult eagles for research purposes is ... a way around the problem, and, in the process, gathered ... hand on one. "Many birds are small, easy to ... and natural resources. "With eagles, the effort can be 100 ...
... CSIRO science is being used to improve land management ... nutrients and pesticides on to the Great Barrier Reef. ... CSIRO, Australian Government Reef Rescue team and the Bureau ... how it allocates more than $50 million between reef ...
Cached Biology News:Nitrogen research shows how some plants invade, take over others 2Scientists are learning more about big birds from feathers 2Investing wisely to save the Great Barrier Reef 2
(Date:9/30/2014)... available in German . ... Mnchen (TUM) have demonstrated a new kind of building ... future computer chips could be based on three-dimensional arrangements ... enabling technology of the semiconductor industry CMOS fabrication ... researchers and collaborators at the University of Notre Dame ...
(Date:9/30/2014)... Sept. 30, 2014 Pacific Northwest Biotechnology, ... Summary Global Markets Direct,s, ,Pacific Northwest Biotechnology, ... an overview of the Pacific Northwest Biotechnology, LLC,s ... provides comprehensive information on the current therapeutic developmental ... comparative analysis at various stages, therapeutics assessment by ...
(Date:9/30/2014)... Shimadzu Scientific Instruments has released the ... precise tool for measuring displacement in rubber and ... maximum movement distance, the DSES-1000 can measure elongations ... of 10 mm. In addition, it achieves +/- ... and within +/- 100 µm below 50-mm stroke. ...
(Date:9/30/2014)... 30, 2014 Over the last decade, ... to rising R&D budgets and increased acceptance of new ... pharmaceutical and biotechnology industries are also catalyzing the growth ... market is expected to grow at a strong CAGR ... to be worth $2,532.6 million by 2019. The market ...
Breaking Biology Technology:A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 2Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 3Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 2Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 3Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 4Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 5
... SUNNYVALE, Calif., Sept. 26 Cepheid (Nasdaq:,CPHD) will ... Growth Stock,Conference on October 3, 2007 at 10:40 ... York. John R. Sluis, Cepheid,s Chief Financial Officer ... Officer, will provide,a corporate overview. The webcast, ...
... strategic platform for reducing risk of cancer ... drug development, ... ; MTAX) held its 2007 annual shareholders meeting,(Annual Meeting) on Tuesday, September ... a majority of CTI,s shares are,held by Italian shareholders. At the 2007 ...
... BioInformatics, SINGAPORE, Sept. 26 /Xinhua-PRNewswire/ -- ... Ltd, a leader in reconfigurable computing,applications headquartered ... The,BioIT Alliance is a cross-industry group working ... pace of drug discovery and realize the,potential ...
Cached Biology Technology:Cepheid to Present at William Blair Small-Cap Growth Stock Conference 2Cell Therapeutics, Inc. (CTI) Announces 2007 Annual Shareholders Meeting Results 2Cell Therapeutics, Inc. (CTI) Announces 2007 Annual Shareholders Meeting Results 3Cell Therapeutics, Inc. (CTI) Announces 2007 Annual Shareholders Meeting Results 4Progeniq Joins Microsoft in Bio IT Alliance 2Progeniq Joins Microsoft in Bio IT Alliance 3
Collected from animals that are 16 to 18 months old. Sterile, Cell culture tested, ID clarifier: USA Origin...
... 20-HETE is a cytochrome P450 (CYP450) metabolite ... the renal and cerebral vasculature. In rat ... mediates pressure-induced autoregulatory vasoconstriction. 20-HETE is excreted ... of free 20-HETE (20-40 pg/ml in human ...
... GPS-M Mutagenesis System enables you to insert ... into,your target DNA by in vitro transposition. ... Tn7-based,transposon randomly into the DNA target. Target ... or purified,chromosomal DNA, depending on your interests ...
A set of five peptides which can be used to calibrate a Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) or Electrospray Ionization (ESI) mass spectrometer....
Biology Products: