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Subtle changes in PTEN tumor suppressor gene can determine cancer susceptibility
Date:4/23/2010

y the authors, is tremendously relevant for how genetic alterations in cancer are detected, studied, evaluated and treated. "From a diagnostic perspective, our findings encourage the implementation of quantitative methods to evaluate cancer gene expression levels, and the design of therapies oriented to target these alterations," they write. Adds Pandolfi, "Our immediate aim is to develop a genetic test to be used for the screening of patients at risk of developing breast cancer. Such a test might also be useful in predicting the outcome of certain treatments [i.e. Trastuzumab] for breast cancer patients."


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Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3

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