Navigation Links
Substance in breast milk kills cancer cells
Date:4/19/2010

A substance found in breast milk can kill cancer cells, reveal studies carried out by researchers at Lund University and the University of Gothenburg, Sweden.

Although the special substance, known as HAMLET (Human Alpha-lactalbumin Made LEthal to Tumour cells), was discovered in breast milk several years ago, it is only now that it has been possible to test it on humans. Patients with cancer of the bladder who were treated with the substance excreted dead cancer cells in their urine after each treatment, which has given rise to hopes that it can be developed into medication for cancer care in the future.

Discovered by chance

HAMLET was discovered by chance when researchers were studying the antibacterial properties of breast milk. Further studies showed that HAMLET comprises a protein and a fatty acid that are both found naturally in breast milk. So far, however, it has not been proven that the HAMLET complex is spontaneously formed in the milk. It is speculated, however, that HAMLET can form in the acidic environment of the babies stomachs. Laboratory experiments have shown that HAMLET kills 40 different types of cancer, and the researchers are now going on to study its effect on skin cancer, tumours in the mucous membranes and brain tumours. Importantly, HAMLET kills only cancer cells and does not affect healthy cells.

Studying the integration of the substance

Researchers at the University of Gothenburg are focusing on how HAMLET can be taken up into tumour cells. The researchers, Roger Karlsson, Maja Puchades and Ingela Lanekoff, are attempting to gain an in-depth understanding of how the substance interacts with cell membranes, and their findings were recently published in the prestigious journal PLoS One.


'/>"/>

Contact: Roger Karlsson
rogerk@chem.gu.se
46-317-869-059
University of Gothenburg
Source:Eurekalert  

Page: 1

Related biology news :

1. Healing haze: Substances in smoke left over from forest fires speed plant growth
2. Invasive fish and mussels team up to transfer toxic substances into Great Lakes walleyes
3. Pathological gambling may be successfully treated with medications for substance addiction
4. Smokeless tobacco called moist snuff is contaminated with harmful substances
5. Exposure to alkaline substances can result in damaged teeth
6. Heat forms potentially harmful substance in high-fructose corn syrup
7. Can an over-the-counter vitamin-like substance slow the progression of Parkinsons disease?
8. Airway cells use tasting mechanism to detect and clear harmful substances
9. Natural brain substance blocks weight gain in mice, UT Southwestern researchers discover
10. UI researchers find potentially toxic substance present in Chicago air
11. Substance found in fruits and vegetables reduces likelihood of the flu
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Substance in breast milk kills cancer cells
(Date:3/9/2017)... , March 9, 2017 4Dx has publicly ... Lung Imaging Workshop at the University of Pennsylvania. Founder ... to deliver the latest data to world leaders in ... brings together leaders at the forefront of the industry ... imaging. "The quality of the imaging ...
(Date:3/7/2017)... March 7, 2017 Brandwatch , the leading social ... The Prince,s Trust to uncover insights to support its reporting, ... The UK,s leading youth charity will be using Brandwatch ... and get a better understanding of the topics and issues that ... ...
(Date:3/6/2017)... , March 6, 2017 Mintigo ... technology, today announced Predictive Sales Coach TM , ... actionable sales intelligence into Salesforce. This unique AI ... their sales organizations with deep knowledge of their ... for intelligent engagement. Predictive Sales Coach extends Mintigo,s ...
Breaking Biology News(10 mins):
(Date:3/29/2017)... , March 29, 2017  Halozyme Therapeutics, Inc. ... and drug-delivery therapies, today announced that an Oncologic ... Drug Administration voted 11 to 0 that the ... injection was favorable for patients in the proposed ... and chronic lymphocytic leukemia. The FDA action date ...
(Date:3/29/2017)... (PRWEB) , ... March 29, 2017 , ... Bactana Animal ... hormones in the world’s food supply through enhancement of the gut microbiota, today announced ... included Connecticut Innovations , New York-based Sustainable Income Capital Management, LLC and a ...
(Date:3/29/2017)... 2017 /PRNewswire/ -  GeneNews Limited (TSX:GEN) ("GeneNews" or the ... new risk stratification test for breast cancer, via its ... ("IDL"). BreastSentry incorporates a blood-based biomarker test with a sophisticated ... developing breast cancer.   ... BreastSentry measures the fasting plasma levels of ...
(Date:3/28/2017)... ... March 28, 2017 , ... NetDimensions announced today that ... enhance training plan management for consistent implementation of standards and regulatory requirements across ... Group to help improve and streamline their training and employee development programs, which ...
Breaking Biology Technology: