Navigation Links
Study shows that suffocating head lice works in new treatment
Date:2/24/2010

A new non-neurotoxic treatment for head lice has been found to have an average of 91.2% treatment success rate after one week, and to be safe in humans from six months of age and up. This is the finding of a study published today in Pediatric Dermatology.

Benzyl Alcohol Lotion 5% (known as UlesfiaTM) works by suffocating lice, a method which has been attempted by treating with household items such as mayonnaise, olive oil and petroleum jelly. Studies have shown that overnight treatments with these home remedies may initially appear to kill lice, but later a "resurrection effect" occurs after rinsing, because lice can resist asphyxiation. This is accomplished by the louse's ability to presumably close its spiracles, the external entry points to the breathing apparatus, when submerged. Unlike commonly used asphyxiant remedies, scanning electron microscopy appears to indicate that benzyl alcohol lotion effectively asphyxiates lice by "stunning" the spiracles open, allowing the lotion, comprised of mineral oil and other inactive ingredients, to infiltrate the "honeycomb" respiratory apparatus and kill lice.

The phase III trials were comprised of two multicenter, randomized, double-blind, placebo-controlled trials, conducted among ten geographically diverse sites which assessed the clinical effectiveness and safety of benzyl alcohol lotion. 250 participants took part in the trials and were randomised to treatment or vehicle (lotion but with no active ingredient) groups, treatment was given at day one and day seven, and participants were checked for success at day eight and day 14. On day eight the treatment group had a success rate of 91.2% as an average of both trials, and a 75.6% success rate on day 14; in the vehicle group the success rates were 27.9% and 15.5% respectively.

"Existing over-the-counter head lice treatments contain neurotoxic pesticides as active ingredients, resulting in potential toxicity and other problems, including lengthy applications, odor, ineffective treatment. Resistance has also become a problem now that lice have had such prolonged exposure to these products," said study author Terri L Meinking, PhD, of Global Health Associates of Miami, USA. "This leaves practitioners, parents and patients hoping for a safe, non-neurotoxic cure."

"Since the most popular products have been made readily available, their overuse has caused lice to become resistant just as bacteria have become resistant to many antibiotics," added Meinking. "Because benzyl alcohol lotion kills by suffocation, resistance should not be an issue."


'/>"/>

Contact: Jennifer Beal
medicalnews@wiley.com
44-12-437-70633
Wiley-Blackwell
Source:Eurekalert

Related biology news :

1. Michigan State uses NSF grant to study evolution in action
2. Study highlights sustainable footprint of chemical companies
3. Stress raises risk of mental decline in older diabetics, study shows
4. New study finds link between marine algae and whale diversity over time
5. Study finds variations in 1 gene may be associated with endurance running
6. Study: Crickets forewarn unborn babies about spiders
7. Study examines family lineage of King Tut, his possible cause of death
8. Butterfly vision, wing colors linked, UCI study finds
9. New study possibly links cognitive and motor delays with flat head syndrome in young babies
10. Tobacco use linked to worse outcomes in HPV-positive head and neck cancer, U-M study finds
11. Study finds that long-distance migration shapes butterfly wings
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/25/2016)... 2016  Glencoe Software, the world-leading supplier of image ... will provide the data management solution OMERO Plus for ... Photo - ... Phenotypic analysis measures the characteristics and behavior ... between states such as health and disease, the presence ...
(Date:1/20/2016)... , Jan. 20, 2016   MedNet Solutions , ... entire spectrum of clinical research, is pleased to announce ... significant achievements are the result of the company,s laser ... iMedNet eClinical , it,s comprehensive, easy-to-use and highly ... --> Key MedNet growth achievements in 2015 ...
(Date:1/13/2016)... , January 13, 2016 /PRNewswire/ ... announced the addition of the  "India ... Estimation & Forecast (2015-2020)"  report ... http://www.researchandmarkets.com/research/7h6hnn/india_biometrics ) has announced the addition ... Identification Market - Estimation & Forecast ...
Breaking Biology News(10 mins):
(Date:2/10/2016)...  Allergan plc (NYSE: AGN ) a leading ... , Allergan,s CEO and President, will be featured as ... the RBC Capital Markets Healthcare Conference on Tuesday, February ... York Palace Hotel in New York, NY ... can be accessed on Allergan,s Investor Relations web site ...
(Date:2/10/2016)... ... February 10, 2016 , ... LATHAM, NEW YORK... Marktech ... SPIE Photonics West conference in San Francisco’s Moscone Center from February 16-18, 2016, ... venue. , These latest InGaAs PIN diode standard packages feature a TO-46 metal ...
(Date:2/10/2016)... ... February 10, 2016 , ... Global Stem Cells Group, ... Singapore-based Global Stem Cells Network (GSCN) and its affiliate Global Medical Training ... latest adipose and bone marrow therapies. , Through the new collaboration, Global ...
(Date:2/9/2016)... , Feb. 9, 2016  Regenicin, Inc. (OTC ... specializing in the development and commercialization of regenerative ... tissues and organs, recently reported the Company,s operating ... quarter of 2016. Lonza America , ... 2015 fiscal year in the process of consummating ...
Breaking Biology Technology: