Navigation Links
Study shows that impulsivity is risk factor for food addiction
Date:5/6/2014

(Boston) Have you ever said to yourself that you would only have a handful of potato chips from the bag then, minutes later, realized you ate the whole thing? A recent study shows that this type of impulsive behavior might not be easily controlled and could be a risk factor in the development of food addiction and eating disorders as a result of cellular activities in the part of the brain involved with reward.

The research, published online in Neuropsychopharmacology, was led by Boston University School of Medicine (BUSM) and conducted in collaboration with the University of Cambridge in the United Kingdom. It also points out the common mechanisms involved between drug and food addiction.

Research has shown that people with eating disorders and obesity are known to be more impulsive than healthy people. For example, they may be more likely to blurt out something that they later regret saying or to start an activity without thinking through the consequences. However, it was unclear whether the impulsivity existed before the dysfunctional eating behavior or if developed as a result of it.

BUSM researchers attempted to answer this question by measuring the inability to withhold an impulsive response in experimental models that were exposed to a diet high in sugar daily for one hour. Models shown to be more impulsive rapidly developed binge eating, showing heightened cravings and the loss of control over the junk diet (measured as inability to properly evaluate the negative consequences associated with ingestion of the sugary diet). Conversely, models shown to be less impulsive demonstrated the ability to appropriately control impulsive behavior and did not show abnormal eating behavior when exposed to the sugary diet.

Interestingly, the impulsive models showed increased expression of a transcription factor called Delta-FosB in the nucleus accumbens, an area of the brain involved in reward evaluation and impulsive behavior, indicating a potential biological component to this behavior.

"While impulsivity might have aided ancestors to choose calorie-rich foods when food was scarce, our study results suggest that, in today's calorie-rich environment, impulsivity promotes pathological overeating," said Pietro Cottone, PhD, co-director of the Laboratory of Addictive Disorders and associate professor of pharmacology and psychiatry at BUSM.

"Our results add further evidence to the idea that there are similar mechanisms involved in both drug and food addiction behavior," said Clara Velazquez-Sanchez, PhD, postdoctoral fellow in the Laboratory of Addictive Disorder and first author of the study.


'/>"/>

Contact: Jenny Eriksen Leary
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

Related biology news :

1. Novel antioxidant makes old arteries seem young again, CU-Boulder study finds
2. Immune cells outsmart bacterial infection by dying, Penn Vet study shows
3. Tracking turtles through time, Dartmouth-led study may resolve evolutionary debate
4. History to blame for slow crop taming: Study
5. Study exposes risk of nutritional deficiencies in obese teens
6. Study in Science finds missing piece of biogeochemical puzzle in aquifers
7. Salk Institute study identifies novel regulator of key gene expression in cancer
8. Neanderthals were not inferior to modern humans, says CU-Boulder study
9. Study questions Neandertal inferiority to early modern humans
10. Mouse study points to potentially powerful tool for treating damaged hearts
11. Consuming high-protein breakfasts helps women maintain glucose control, MU study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/21/2016)... -- Unique technology combines v ...   Xura, Inc. (NASDAQ: ... communications services, today announced it is working alongside SpeechPro ... particularly those in the Financial Services Sector, the ability ... a mobile app, alongside, and in combination with, traditional ...
(Date:3/15/2016)... 15, 2016 Yissum Research Development Company ... company of the Hebrew University, announced today the formation ... technology of various human biological indicators. Neteera Technologies has ... from private investors. ... detection of electromagnetic emissions from sweat ducts, enables reliable ...
(Date:3/11/2016)... , March 11, 2016 ... new market research report "Image Recognition Market by Technology ... (Marketing and Advertising), by Deployment Type (On-Premises and Cloud), ... To 2022", published by MarketsandMarkets, the global market is ... to USD 29.98 Billion by 2020, at a CAGR ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... manufacturing company, today announced several positive developments that position the Company for the ... result of the transaction, Craig F. Kinghorn has been appointed Chairman of the ...
(Date:5/25/2016)... ... 2016 , ... Founder of the Fitzmaurice Hand Institute in ... of the hand by the National Board of Physicians and Surgeons, as of ... in his pursuit of providing the most comprehensive, effective treatment for his patients, ...
(Date:5/25/2016)... ... May 25, 2016 , ... Biohaven Pharmaceutical Holding Company Ltd. ... the company’s orphan drug designation request covering BHV-4157 for the treatment of Spinocerebellar ... FDA. , Spinocerebellar ataxia is a rare, debilitating neurodegenerative disorder that is ...
(Date:5/23/2016)... ... ... need for blood donations in South Texas and across the nation is growing. , But ... blood donations are on the decline. In fact, donations across the country are at their ... Texas in the last four years alone. , There is no substitute for blood. , ...
Breaking Biology Technology: