Navigation Links
Study shows that diet of resistant starch helps the body resist colorectal cancer
Date:2/19/2013

As the name suggests, you can't digest resistant starch so it ends up in the bowel in pretty much the same form it entered your mouth. As unlovely as that seems, once in the bowel this resistant starch does some important things, including decreasing bowel pH and transit time, and increasing the production of short-chain fatty acids. These effects promote the growth of good bugs while keeping bad bugs at bay. A University of Colorado Cancer Center review published in this month's issue of the journal Current Opinion in Gastroenterology shows that resistant starch also helps the body resist colorectal cancer through mechanisms including killing pre-cancerous cells and reducing inflammation that can otherwise promote cancer.

"Resistant starch is found in peas, beans and other legumes, green bananas, and also in cooked and cooled starchy products like sushi rice and pasta salad. You have to consume it at room temperate or below as soon as you heat it, the resistant starch is gone. But consumed correctly, it appears to kill pre-cancerous cells in the bowel," says Janine Higgins, PhD, CU Cancer Center investigator and associate professor of Pediatrics at the University of Colorado School of Medicine.

Higgins describes studies showing that rats fed resistant starch show decreased numbers and sizes of lesions due to colorectal cancer, and an increased number of cells that express the protein IL-10, which acts to regulate the body's inflammatory response.

"Resistant starch may also have implications for the prevention of breast cancer," Higgins says. "For example, if you let rats get obese, get them to lose the weight, and then feed half of the rats a diet high in resistant starch these rats don't gain back the weight as fast as rats fed a regular, digestible starch diet. This effect on obesity may help to reduce breast cancer risk as well as having implications for the treatment of colorectal cancer."

"There are a lot of things that feed into the same model of resistant starch as a cancer-protective agent," Higgins says. "Much of this information currently comes from rodent models and small clinical trials but the evidence is encouraging." On the table now is a menu of benefits and while it's just now being studied which benefits, exactly, will pan out as mechanisms of cancer prevention, one thing is clear: resistant starch should be on the menu.


'/>"/>

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. Breakthrough study opens door to broader biomedical applications for Raman spectroscopy
2. Phosphorus starvation linked to symptoms of citrus disease Huanglongbing in new study
3. Yale Study links common chemicals to osteoarthritis
4. CU-Boulder amphibian study shows how biodiversity can protect against disease
5. Busy beavers give Canada geese a lift, study shows
6. Video study shows which fish clean up coral reefs, showing importance of biodiversity
7. UCSB study of cocaine addiction reveals targets for treatment
8. Study in mice yields Angelman advance
9. Southwest regional warming likely cause of pinyon pine cone decline, says CU study
10. Nature Methods study: Using light to control cell clustering
11. New study finds neither HFCS nor table sugar increases liver fat under real world conditions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/7/2017)... Feb. 7, 2017   MedNet Solutions , an ... spectrum of clinical research, is pleased to announce that ... its innovative, highly flexible and award winning eClinical solution, ... iMedNet is a proven Software-as-a-Service (SaaS) clinical ... Capture (EDC), but also delivers an entire suite of ...
(Date:2/3/2017)... Feb. 3, 2017  Texas Biomedical Research Institute announced that ... Larry Schlesinger as the Institute,s new President and CEO. ... May 31, 2017. He is currently the Chair of the ... Center for Microbial Interface Biology at Ohio State University. ... new President and CEO of Texas Biomed," said Dr. ...
(Date:2/2/2017)... TOKYO , Feb. 1, 2017  Central ... innovative and meaningful advances worldwide, The Japan Prize ... Japan Prize, who have pushed the envelope in ... Information and Communication. Three scientists are being recognized ... outstanding achievements that not only contribute to the ...
Breaking Biology News(10 mins):
(Date:2/23/2017)...  In Atlanta, it seems everyone has a chance to ... create an expressive and dynamic community unlike any other. The ... to it. With their newest salon in ... to carry on that tradition with a unique, fresh approach ... salon is the newest of 13 nationwide locations, each of ...
(Date:2/23/2017)... ... 2017 , ... David Nolte, PhD accepted Purdue University’s 2016 ... Research Park of West Lafayette, Indiana. , The top commercialization award is ... success with, commercializing discoveries from Purdue research. “This award is truly an honor. ...
(Date:2/23/2017)... SAN FRANCISCO , Feb. 23, 2017   ... Beyond Type 1, a not-for-profit advocacy and education group ... a grant from Beyond Type 1 to support ViaCyte,s ... and other insulin-requiring diabetes.  For more ... cell-derived cell replacement therapies with a focus on the ...
(Date:2/22/2017)... SAN DIEGO , Feb. 22, 2017  PrimeVax ... , will be presenting at the Annual Biocom Global ... on March 2, at 11:15 AM, at the Torrey ... are thankful to the organizers at Biocom who have ... this international symposium of biotechnology companies, investors, and clinical ...
Breaking Biology Technology: