Montreal, June 19, 2013 A study published in the Journal of Clinical Endocrinology & Metabolism is the first report of an oral probiotic supplement significantly increasing circulating vitamin D levels in the blood.
The lead author on the study, Mitchell Jones, MD, PhD, received the Early Career Investigator Poster Presentation Prize from the New York Academy of Sciences and the Sackler Institute for Nutrition Science at last week's Probiotics, Prebiotics, and the Host Microbiome: The Science of Translation conference in New York City(1).
The study(2) , a post-hoc analysis of a published randomized controlled trial, examined the effect of Lactobacillus reuteri NCIMB 30242 on fat-soluble vitamins. It showed that L. reuteri NCIMB 30242 increased circulating 25-hydroxyvitamin D levels by 25.5 percent in hypercholesterolemic adults over the nine-week intervention.
According to the National Institutes of Health, serum concentration of 25-hydroxyvitamin D is the best indicator of vitamin D status, and is important for adequate bone and overall health in healthy individuals(3). More than 40 million adults in the United States have or are at risk of developing osteoporosis, a disease most often associated with inadequate calcium intake. Insufficient vitamin D contributes to osteoporosis by reducing calcium absorption(4) . Researchers continue to study other possible health effects of vitamin D, such as protection against heart disease, autoimmune diseases, and diabetes.
The Institute of Medicine recommends 600 IUs of vitamin D daily to meet the needs of almost everyone in the United States and Canada. Most people get vitamin D through sun exposure, foods that contain it, and supplements. A variety of factors may reduce vitamin D absorption, including limited exposure to sunlight, dark skin, obesity, and problems with absorption or ability to convert vitamin D to its active form.
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