Navigation Links
Study shows compulsive eating shares addictive biochemical mechanism with cocaine, heroin abuse
Date:3/28/2010

JUPITER, FL, March 23, 2010 In a newly published study, scientists from The Scripps Research Institute have shown for the first time that the same molecular mechanisms that drive people into drug addiction are behind the compulsion to overeat, pushing people into obesity.

The new study, conducted by Scripps Research Associate Professor Paul J. Kenny and graduate student Paul M. Johnson, was published March 28, 2010 in an advance online edition of the journal Nature Neuroscience.

The study's startling findings received widespread publicity after a preliminary abstract was presented at a Society for Neuroscience meeting in Chicago last October. Articles heralding the new discovery appeared in news publications around the world, focusing on the point obese patients have been making for years that, like addiction to other substances, junk food binging is extremely difficult to stop.

The study goes significantly further than the abstract, however, demonstrating clearly that in rat models the development of obesity coincides with a progressively deteriorating chemical balance in reward brain circuitries. As these pleasure centers in the brain become less and less responsive, rats quickly develop compulsive overeating habits, consuming larger quantities of high-calorie, high-fat foods until they become obese. The very same changes occur in the brains of rats that overconsume cocaine or heroin, and are thought to play an important role in the development of compulsive drug use.

Kenny, a scientist at Scripps Research's Florida campus, said that the study, which took nearly three years to complete, confirms the "addictive" properties of junk food.

"The new study, unlike our preliminary abstract, explains what happens in the brain of these animals when they have easy access to high-calorie, high-fat food," said Kenny. "It presents the most thorough and compelling evidence that drug addiction and obesity are based on th
'/>"/>

Contact: Keith McKeown
kmckeown@scripps.edu
858-784-8134
Scripps Research Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Single gene dramatically boosts yield, sweetness in tomato hybrids, CSHL-Israeli study finds
2. Rochester study connects workplace turmoil, stress and obesity
3. Rodeo bull goes head-to-head with zoo dolphins in a study of balance
4. New study may explain how weight-loss surgery reverses type 2 diabetes
5. To close achievement gap, US must address major health risks for urban minority youth, study finds
6. Tectonics: Precision is hallmark of 20-year study
7. Study explores link between sunlight, multiple sclerosis
8. Study finds genes that keep watch on blood clotting time
9. WPI receives $1.2 million NIST award for pioneering study of wireless body area networks
10. Study details machinery of immune protection against inflammatory diseases like colitis
11. A marine Mr. Mom: Male pipefish gives birth, but some are deadbeat dads, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)...  Automation is fundamentally transforming the travel experience ... international borders. Over the past decade, ePassports, biometric ... travelers to self process through border control via ... an increasing number of airports, seaports, and land ... to Maxine Most , Principal at Acuity ...
(Date:12/11/2014)... 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition ... report to their offering. ... the adoption of multimodal biometric systems. Multimodal biometric ... individual for verification and identification purposes. This helps ...
(Date:12/10/2014)... , Dec. 8, 2014 You,ve been here ... account but can,t remember your password, site key or the ... was your first grade teacher? Today, ... the app that will finally put an end to ... 1U TM . 1U leverages a user,s smartphone ...
Breaking Biology News(10 mins):Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... sclerosis is caused by a combination of genetic and ... to be such external influences. According to scientists from ... it is apparently not harmful bacteria that trigger ... intestinal flora, which every human being needs for digestion. ...
... such as microscopy play a central role. The technique ... method in this field that promises many benefits. This ... Committee of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) ... in the Life Sciences" initiative, to equip nine universities ...
... PROVO, Utah, Oct. 27, 2011 Nu Skin Enterprises, ... announce that it has executed a letter of intent ... in Madison, Wisconsin for $11,662,500. The letter of intent ... of LifeGen, including its tissue bank, proprietary gene expression ...
Cached Biology News:Natural intestinal flora involved in the emergence of multiple sclerosis 2Natural intestinal flora involved in the emergence of multiple sclerosis 3On the trail of biomarkers and signalling substances with major instrumentation 2Nu Skin Enterprises Enters Into a Letter of Intent to Acquire LifeGen Technologies 2Nu Skin Enterprises Enters Into a Letter of Intent to Acquire LifeGen Technologies 3Nu Skin Enterprises Enters Into a Letter of Intent to Acquire LifeGen Technologies 4
(Date:12/19/2014)... 19, 2014 In contrast to traditional ... with various colors, Valoya uses proprietary LED technology to ... best possible uniformity which is critical in low proximity ... spectral accuracy throughout its lifetime which is up to ... , "The investment cost was clearly higher when ...
(Date:12/19/2014)... 2014 With only 2 weeks left ... on Sartorius Biohit products . The product specials include ... Electronic Pipette Trade-in Program, and free pipette tips. , ... around the world. They are ideal for lab technicians ... ,     Full volume range of 0.1 uL ...
(Date:12/19/2014)... -- Egenix, Inc. is pleased to announce that Lionel ... to succeed Donald Fresne ; Mr. Fresne has also ... member of the Board.  In recognition of the many contributions ... almost twenty years, the Board designated Mr. Fresne as Chairman ... a Search Committee to find a suitable replacement with Biotech ...
(Date:12/19/2014)... Relmada Therapeutics, Inc. (OTCQB: RLMD), a clinical-stage ... pain, announced the results of its annual general meeting ... transformational year in Relmada,s history and it set the ... Sergio Traversa , chief executive officer of Relmada. ... financial, human resource and clinical development objectives that position ...
Breaking Biology Technology:Major Pipette Distributor Pipette.com Announces Sartorius Year End Specials 2Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2
... New campus will accommodate planned company growth , ... at General Robotics and was struck by the entrepreneurial ... time clock, still found in many businesses today. Twenty-two ... and is expanding his recently renamed healthcare software company ...
... from the U.S. Environmental Protection Agency , ... investigate what happens if infectious prion proteins - ... mad cow disease - enter wastewater treatment plants. ... and ,a href="http://www.soils.wisc.edu/soils/people/faculty/pedersen.htm" target="blank">Joel Pedersen currently investigating ...
... , which provides molecular cloning products to genetics researchers, has ... clone genes that may solve a persistent problem in ... they analyze genes using standard methods, explained Ron Godiska, a ... of DNA that react poorly to standard cloning techniques, which ...
Cached Biology Technology:API Software continues expansion 2Researchers to study fate of prions in wastewater 2Lucigen aims to fill holes in genetic maps with new technique 2
Goat polyclonal to Haptoglobin ( Abpromise for all tested applications). Antigen: Affinity purified human haptoglobin. Entrez GeneID: 3240 Swiss Protein ID: P00738...
... Pyruvate Kinase. This product is ... from other mammalian species but has ... Gives a single precipitin line against ... been shown to react with all ...
Recorder, 6", 7 Day, 1 Pen, 0 to 100°C, 220V, 50/60 Hz, for 4520, Customer Installed...
... Shimadzu Phoretix 2D, Expression and Evolution supports ... comparative gel analysis studies in determining differential ... on component Oracle data base ... 2 client software). Supports advanced ...
Biology Products: