Navigation Links
Study reveals that financial conflicts of interest are associated with positive study outcomes
Date:5/27/2011

Results demonstrate that 91% of RCTs recording this kind of FCOI achieved a positive - outcome, compared to 66.7% of RCTs without specific FCOI (p=0.02) and adjusting for confounding factors did not change this finding.

Results of this American study demonstrate that between the two periods 2002-3 and 2006-7 there was a significant increase in the number of RA RCTs listing lead authors as receiving consulting fees/honoraria (14.6% in the first time period compared to 40% in the second (p=0.004)). FCOIs including research grants, employment by sponsoring pharmaceutical company and share ownership were disclosed by at least one author in 53.4% of the 103 eligible RCTs studied. It could be possible that the difference noted between the two periods simply reflects a natural increase in the number of authors proactively reporting conflicts of interest.

"The number of pharmaceutical treatment options for RA has increased remarkably in recent years, partly as a result of increased funding from pharmaceutical companies," said Dr. Khan an Assistant Professor from the Division of Rheumatology at the University of Arkansas for Medical Sciences, USA. "Our study has shown that certain FCOIs among study authors have an increased likelihood of positive outcomes favouring the sponsor‟s drug. There are many potential reasons for these results it could be possible that more experienced clinicians hired by industry have a greater likelihood of achieving positive results because of superior trial design or that positive trials results are more likely to be published than negative ones."

FCOIs were disclosed by at least one author in 55 of the 103 (53.4%) eligible RCTs assessed by the study authors. Forty nine (47.6%) were employed by the industry sponsor, 29 (28.2%) had received consulting fees/honoraria, 14 (13.6%) had received research grants, and 13 (12.6%) owned shares in the pharmaceutical company. However, study authors found the correlation
'/>"/>

Contact: Rory Berrie
rory.berrie@cohnwolfe.com
44-790-151-3297
European League Against Rheumatism
Source:Eurekalert

Page: 1 2

Related biology news :

1. TGen study identifies compounds that could slow down Alzheimers disease
2. Study finds 2 gene classes linked to new prion formation
3. New study suggests link between chronic estrogen exposure and high blood pressure
4. Study confirms link between rheumatoid arthritis and COPD
5. Study shows the HPV vaccine Gardasil doesnt increase disease activity in SLE patients
6. Study reveals most biologically rich island in Southern Ocean
7. Study details path to sustainable aviation biofuels industry in Northwest
8. Global warming may affect the capacity of trees to store carbon, MBL study finds
9. New study provides global analysis of seagrass extinction risk
10. Baylor study finds common fire retardant harmful to aquatic life
11. Happy guys finish last, says new study on sexual attractiveness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... Calif. , Nov. 20, 2014   Atmel® ... leader in microcontroller (MCU) and touch technology solutions, today ... temperature sensors with the widest V cc ... higher temperature accuracy and faster I 2 C bus ... and serial EEPROM memory making them ideal for consumer, ...
(Date:11/18/2014)... , Nov. 17, 2014 The Parenteral Drug ... U.S. regulatory agencies will speak and at least seven more ... Conference at the Omni Shoreham Hotel in Washington ... once again to have significant support from the regulatory agencies ... Europe in our effort to help advance ...
(Date:11/12/2014)... BEACH GARDENS, Fla. , Nov. 12, 2014 /PRNewswire/ ... solutions, announced today that its U.are.U ® fingerprint ... retail bakery chain in Central Mexico ... in June 2014 to eliminate payroll issues caused by ... Prior to installing the U.are.U fingerprint readers, Montparnasse relied ...
Breaking Biology News(10 mins):Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Montparnasse Pasteleria Achieves Time and Attendance Transparency with Crossmatch U.are.U Fingerprint Readers 2
... That,s the agonizing choice some birds face, according to ... by Guelph researchers discovered that for some male birds traveling ... attracting a female when they return home. Alice Boyle, a ... Chris Guglielmo, a biologist at the University of Western Ontario, ...
... New York City,s S.L.E. Lupus Foundation is pleased to ... Basic Science Fellowships: Josephine Isgro, MD of Hospital for ... Medical Center, and Yi Yan, PhD of the Feinstein ... These grants, totaling $420,000, push the S.L.E. Lupus Foundation,s ...
... in the journal PLoS Biology , scientists from ... systems to produce goods and services to humanity increases ... populations hamper the ability of reefs to function normally, ... the greatest impairments from stressors triggered by human populations. ...
Cached Biology News:Birds must choose between mating, migrating, study finds 2S.L.E. Lupus Foundation announces new grants to further NYC scientists' leadership in lupus research 2S.L.E. Lupus Foundation announces new grants to further NYC scientists' leadership in lupus research 3World's reef fishes tussling with human overpopulation 2World's reef fishes tussling with human overpopulation 3World's reef fishes tussling with human overpopulation 4
(Date:11/26/2014)... 26, 2014 The Alliance for ... survey of European physicians at the "1 ST ... Biological Therapies" at the Spanish Ministry of Health, ... EuropaBio and the Spanish Bioindustry Association (ASEBIO), included ... from Spanish oncology and rheumatology societies, representatives from ...
(Date:11/26/2014)... SonaCare Medical, a leading manufacturer of ... participated in the American Urology Association’s (AUA) surgical ... opinion leaders in urology presented on the latest ... masses while attendees had the opportunity to evaluate ... labs. Attendees at the Los Angeles, CA lab, ...
(Date:11/26/2014)... November 25, 2014 Miles Holder, formerly ... the Graphel Carbon Products team as Sales/Marketing Manager. Mr. ... and customer service for the graphite industry. , “We ... our team,” stated Dave Trinkley, VP of Market and ... range of experience in the graphite industry, along with ...
(Date:11/26/2014)... , Nov. 25, 2014 Bio-Techne Corporation ... has appointed Robert Gavin to serve in ... the Protein Platforms Division.  Mr. Gavin will be responsible ... segment, which includes the ProteinSimple business acquired in July ... San Jose, California -based ProteinSimple develops ...
Breaking Biology Technology:ASBM Presents European Physicians Survey at Spanish Ministry of Health 2SonaCare Medical Supports American Urology Association’s Small Renal Mass 360° Summit 2SonaCare Medical Supports American Urology Association’s Small Renal Mass 360° Summit 3Miles Holder Joins Graphel Corporation as Sales/Marketing Manager 2Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 2Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 3
... 2012 Nektar Therapeutics, (Nasdaq: NKTR ) President ... present at the upcoming 30th Annual J.P. Morgan Healthcare Conference ... Wednesday, January 11, 2012 at 8:30 a.m. Pacific time. ... a link posted on the Investor Relations, Events Calendar section ...
... Therapeutics, Inc. (NASDAQ: HALO) will be presenting at the ... on Wednesday, January 11, 2012 at 2:00 p.m. PT ... Ph.D., president and chief executive officer of Halozyme Therapeutics, ... http://photos.prnewswire.com/prnh/20100302/LA63139LOGO ) The presentation will be webcast ...
... MOUNTAIN VIEW, Calif., Jan. 4, 2012  23andMe, a leader ... of what it thinks are the 10 most interesting ... an ongoing journey to understand the role of genetics ... (Logo: http://photos.prnewswire.com/prnh/20110107/NY26598LOGO ) "The genetics ...
Cached Biology Technology:Nektar Therapeutics' President and CEO, Howard W. Robin, to Present at the 30th Annual J.P. Morgan Healthcare Conference in San Francisco, CA 223andMe Presents Top Ten Most Interesting Genetic Findings of 2011 223andMe Presents Top Ten Most Interesting Genetic Findings of 2011 323andMe Presents Top Ten Most Interesting Genetic Findings of 2011 423andMe Presents Top Ten Most Interesting Genetic Findings of 2011 523andMe Presents Top Ten Most Interesting Genetic Findings of 2011 623andMe Presents Top Ten Most Interesting Genetic Findings of 2011 7
... system, 100-120 V, is used for biolistic ... system includes the Helios gene gun, helium ... syringe kit, tubing cutter, Helios gene gun ... dimensions of the gene gun are 20 ...
... is for fine-tuning the bombardment conditions for ... recommended when you are first using the ... 0.25 g each of 0.6 micrometer, 1.0 ... 100 each of 9 rupture disks, 500 ...
... to test the crossreactivity of an antibody ... commonly used as blocking reagents or antigen ... different protein preparations on a nitrocellulose membrane. ... specificity, QC of purified antibodies, selection of ...
... Affinity Life Sciences can provide custom microplate coating using ... washes a variety of plate formats. We can also accommodate ... volume range of 0.5-320 L):, , ... 96 well microplate, ...
Biology Products: