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Study reveals how one form of natural vitamin E protects brain after stroke
Date:1/11/2010

rienol fared much better, too, compared to those exposed to only the damaging levels of glutamate. Cells treated with TCT were almost four times more likely to survive than were cells exposed to glutamate alone.

Though cPLA2 exists naturally in the body, blocking excessive function of this enzyme is not harmful, Sen explained. Scientists have already determined that mice genetically altered so they cannot activate the enzyme achieve their normal life expectancy and carry a lower risk for stroke.

Sen also noted that the amount of tocotrienol needed to achieve these effects is quite small just 250 nanomolar, a concentration about 10 times lower than the average amount of tocotrienol circulating in humans who consume the vitamin regularly.

"So you don't have to gobble up a lot of the nutrient to see these effects," he said.


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Contact: Chandan Sen
chandan.sen@osumc.edu
614-247-7786
Ohio State University
Source:Eurekalert

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