Navigation Links
Study reveals how one form of natural vitamin E protects brain after stroke
Date:1/11/2010

COLUMBUS, Ohio Blocking the function of an enzyme in the brain with a specific kind of vitamin E can prevent nerve cells from dying after a stroke, new research suggests.

In a study using mouse brain cells, scientists found that the tocotrienol form of vitamin E, an alternative to the popular drugstore supplement, stopped the enzyme from releasing fatty acids that eventually kill neurons.

The Ohio State University researchers have been studying how this form of vitamin E protects the brain in animal and cell models for a decade, and intend to pursue tests of its potential to both prevent and treat strokes in humans.

"Our research suggests that the different forms of natural vitamin E have distinct functions. The relatively poorly studied tocotrienol form of natural vitamin E targets specific pathways to protect against neural cell death and rescues the brain after stroke injury," said Chandan Sen, professor and vice chair for research in Ohio State's Department of Surgery and senior author of the study.

"Here, we identify a novel target for tocotrienol that explains how neural cells are protected."

The research appears online and is scheduled for later print publication in the Journal of Neurochemistry.

Vitamin E occurs naturally in eight different forms. The best-known form of vitamin E belongs to a variety called tocopherols. The form of vitamin E in this study, tocotrienol or TCT, is not abundant in the American diet but is available as a nutritional supplement. It is a common component of a typical Southeast Asian diet.

Sen's lab discovered tocotrienol vitamin E's ability to protect the brain 10 years ago. But this current study offers the most specific details about how that protection works, said Sen, who is also a deputy director of Ohio State's Heart and Lung Research Institute.

"We have studied an enzyme that is present all the time, but one that is activated after a stro
'/>"/>

Contact: Chandan Sen
chandan.sen@osumc.edu
614-247-7786
Ohio State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. What came first in the origin of life? A study contradicts the metabolism first hypothesis
2. Study examines calorie information from restaurants, packaged foods
3. Study provides insight into pathway linked to obesity
4. Sweet corn study provides large-scale picture of better fields
5. A global breakthrough in the study of a protein linked to the spread of viruses
6. Using modern sequencing techniques to study ancient modern humans
7. Short-term school closures may worsen flu pandemics, Pitt study finds
8. Researchers use new acoustic tools to study marine mammals and fish
9. Study shows a key protein helps control blood pressure
10. New study finds catch shares improve consistency, not health, of fisheries
11. Michigan State University study sheds light on microscopic flower petal ridges
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/2/2015)... 2, 2015 Fingerprint Cards (FPC) ... FPC1025 from the distributor World Peace Industrial Group (WPI), ... 2015 although the major part of the shipments will ... used by smartphone manufacturers in China ... in the communicated revenue guidance of + 1 000 MSEK ...
(Date:3/31/2015)... March 31, 2015   Guidepoint , a leading ... the Post-Surgical Pain Management TRACKER, part of the ... trends in the medical device and therapeutics markets. The ... including treatment volumes, market share, and adoption rates across ... with joint surgery. The Post-Surgical Pain Management ...
(Date:3/24/2015)... 24, 2015 Research and Markets ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ) ... - Global Strategic Business Report" report to their offering. ... Biometrics in US$ Thousands by the following Segments: Face Biometrics, and ... Canada , Japan , ... Middle East & Africa , and ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6
... environs to take up residence in a large and ... University Bloomington scientists report in this week's Science that ... , "Plants that reproduce clonally or are capable of ... the nucleus," said graduate student Yaniv Brandvain, lead author ...
... and give a short-term boost to cognitive skills, a University ... Professor Ian Macdonald found that consumption of a cocoa drink ... blood flow to key areas of the brain for two ... areas of the brain may help to increase performance in ...
... Dentistry (NYUCD) research team has found the first oral bacterial ... Africa to Asia. , The team, led by ... NYUCD, discovered that Streptoccocus mutans, a bacterium associated with dental ... clear line that can be traced back to a single ...
Cached Biology News:Mitochondrial genes move to the nucleus -- but it's not for the sex 2Boosting brain power -- with chocolate 2'Ancestral eve' was mother of all tooth decay 2
(Date:4/24/2015)... 2015  Navitas Life Sciences is delighted to announce the ... and Regulatory Services. Shalabh is a proven leader in Life ... of Kinapse, as well as a Strategy consultant at Accenture. ... http://photos.prnewswire.com/prnh/20150423/201261LOGO ... am delighted to welcome Shalabh into this critical role and ...
(Date:4/23/2015)... April 24, 2015 Ralco announced today ... Birthright Nutrition® (ABN) for the exclusive worldwide rights to ... new technology is a new in-line milk system that ... allowing them to move supplementation milk cups within a ... , “This technology lets producers get Birthright™ milk to ...
(Date:4/23/2015)... 2015 /CNW/ - A new and innovative service has ... North America,s largest packaging trade ... in the "Sustainability, service" category of the PAC ... Comparison" is a service that scores clients, packaging ... peers. This benchmarking process shows clients how their ...
(Date:4/23/2015)... April 23, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... its first quarter 2015 results before the Nasdaq market ... host a live conference call and webcast to discuss its ... April 30, 2015 at 8:00 a.m. Eastern Time (5:00 ... live conference call by dialing 866-952-1906 (US) or 785-424-1825 ...
Breaking Biology Technology:Shalabh Kumar Joins Navitas Life Sciences to Lead their Clinical and Regulatory Services Teams 2Ralco Acquires License to Birthright™ Moveable Milk Cup 2Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2
... Richard Duffey, M.D., to its LASIK Directory. ... also serves patients from Pensacola, Florida and from ... Mississippi.,Trusted LASIK Surgeons launched its revolutionary Trusted LASIK ... consumers at www.TrustedLASIKSurgeons.com . What sets the ...
... Varian, Inc.,(NasdaqGS: VARI) introduced its new dual wavelength ... proteins. The SuperNova(TM) is the,first dual wavelength diffraction ... It includes innovations in both X-ray,technology and data ... crystals., Single crystal X-ray diffraction is used ...
... Quality and process,improvement efforts gained new momentum ... higher efficiencies fueled by a stagnating economy.,Biopharmaceutical companies ... pipelines are affecting the bottom line, competition for ... brought more scrutiny to R&D,and New Product Development ...
Cached Biology Technology:Trusted LASIK Surgeons Welcomes Mobile Alabama Expert Refractive Eye Surgeon Richard Duffey, M.D. to Its LASIK Directory For Consumers 2Trusted LASIK Surgeons Welcomes Mobile Alabama Expert Refractive Eye Surgeon Richard Duffey, M.D. to Its LASIK Directory For Consumers 3Trusted LASIK Surgeons Welcomes Mobile Alabama Expert Refractive Eye Surgeon Richard Duffey, M.D. to Its LASIK Directory For Consumers 4Trusted LASIK Surgeons Welcomes Mobile Alabama Expert Refractive Eye Surgeon Richard Duffey, M.D. to Its LASIK Directory For Consumers 5Trusted LASIK Surgeons Welcomes Mobile Alabama Expert Refractive Eye Surgeon Richard Duffey, M.D. to Its LASIK Directory For Consumers 6New Dual Wavelength X-ray Diffractometer From Oxford Diffraction, Now a Part of Varian, Inc., Allows Increased Throughput for Challenging Single Crystal Analyses 2Leading Biopharmas Will Deliver Case Studies on Achieving Productivity Excellence through Engagement, Technology, Other Tools 2
Recombinant Equine TNF-alpha/TNFSF1A, CF...
Recombinant Feline IL-2, CF...
... N. Fernandez and G. Butcher (1998). ... subject of much research in the immunology ... structure of MHC proteins and in their ... are now faced with the prospect of ...
VACUGENE PUMP 110V, 1 EA. Category: Nucleid Acid Detection Systems....
Biology Products: