Navigation Links
Study raises new concerns about radiation and breast cancer
Date:5/13/2010

east Cancer Research, titled "Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies." Co-authoring the paper were Rituparna Mukhopadhyay, Sylvain Costes, Alexey Bazarov, William Hines and Mary Helen Barcellos-Hoff.

"The work we did was performed with non-lethal but fairly substantial doses of radiation, unlike what a woman would be exposed to during a routine mammogram," says Yaswen, who is also a member of the Bay Area Breast Cancer and the Environment Research Center. "However, the levels of radiation involved in other procedures, such as CT scans or radiotherapy, do start to approach the levels used in our experiments and could represent sources of concern."

For their study, Yaswen and his collaborators worked with human mammary epithelial cells (HMECs), the cells that line breast ducts, where most breast cancers begin. In a culture dish, the vast majority of breast cells display a phenotype that allows them to divide between five and 20 times before becoming senescent. However, also present are rare variant HMECs, which display a phenotype that allows them to continue dividing for many weeks in culture. This vHMEC phenotype arises spontaneously and is much more susceptible to malignancy because it lacks a tumor-suppressing protein called p16.

To test the effects of radiation on cellular environment and subsequent cell behavior, the research team grew sets of HMECs from normal breast tissue in culture dishes for about a week, then exposed each set to a single treatment of a low-to-moderate dose of radiation. They then compared the irradiated sets to sets of breast cells that were not irradiated. Four to six weeks after the radiation treatments, most of the cells in both the irradiated and unirradiated sets had permanently stopped dividing.

"However, the daughters of breast cells exposed to radiation formed larger, more numerous patches of cells w
'/>"/>

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Opinion polls underestimate Americans concern about the environment, Stanford study finds
2. Study finds protein that plays key role in early embryonic development
3. Scripps Research study overturns decade-old findings in neurobiology
4. UC Davis study links obesity with lowest earnings
5. Montana State grad student to study unique soil around Yellowstone hot springs
6. U-M study achieves reduced side effects in head and neck cancer treatment
7. NTU and UNSW open joint center to study microorganisms for water and environment technologies
8. Study paves way for new biofuels models, technologies
9. NIH awards $7.5 million to study MRI as a tool to evaluate children with muscular dystrophy
10. Study looks at gorillas, elephants and logging in Congo
11. Stream water study detects thawing permafrost
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study raises new concerns about radiation and breast cancer
(Date:5/18/2015)... Sweden , May 18, 2015 ... fingerprint sensors FPC1020, FPC1025, FPC1145, FPC1155 and FPC1035 from one ... from June until and including Q3 2015 and the sensors ... . Communicated order values for 2015 hereby amount to ... for Q1 2015 of 140 MSEK and a number of ...
(Date:5/14/2015)... 2015  Verificient Technologies, Inc., a technology ... remote proctoring, announced a new alliance partnership ... creator of the Canvas Learning Management System ... will benefit from the seamless integration of ... a fully integrated multifactor biometrics behavioral application, ...
(Date:5/11/2015)... Ohio , May 11, 2015  Through a well-rounded ... Ohio had a strong showing at AUVSI,s Unmanned ... These representatives of Ohio,s UAS industry ... and abroad from all points along the UAS ecosystem. ... Development Coalition,s (DDC) Vice President for Aerospace Rich Knoll ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2Ohio Flies High at Unmanned '15, Sets Stage for Ohio UAS Conference 2
... Boulder, Colo., USA New GSA Bulletin articles cover wind ... on Kauai; new insights from the Petrified Forest, USA; a ... a new model for the development of Ries Crater Lake, ... large earthquakes in northern Fiordland, New Zealand; and the evolution ...
... research at the Institute of Food Research, has taken ... and drug companies worldwide. , IFR and the technology ... from the Biotechnology and Biological Sciences Research Council (BBSRC) ... and improve how well it simulates the release of ...
... surrounds the DNA of our cells could help develop treatments ... have discovered that the proteins within this coating known ... different organs of the body. This variation ... proteins in the protective seal to cause illness in some ...
Cached Biology News:Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 2Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 3Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 4Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 5Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 6Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 7Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 8Kauai, the Petrified Forest, Costa Rica, and more: New GSA Bulletin articles now online 9Commercial future for Model Gut 2Cell discovery could hold key to causes of inherited diseases 2
(Date:6/2/2015)... NEWTOWN, Pa. , June 2, 2015   ... services and technology provider, today announced that David ... has been named Executive Vice President and Chief Financial ... 8, 2015. Peters brings more than 25 ... in pharmaceutical services. "David has extensive and deep knowledge ...
(Date:6/2/2015)... , June 2, 2015  Alere Inc. ... rapid diagnostics, joined the White House Antibiotic Stewardship ... commitments to support and advance the President,s National ... commitments include a number of measurable goals and ... achieved, will help healthcare providers protect their patients ...
(Date:6/2/2015)... New Orleans, LA (PRWEB) June 02, 2015 ... of custom gene synthesis to improve protein expression, announced ... The board includes six executives and entrepreneurs with a ... and software industries. , The team includes: , ... Startup Fund: , Roussel has a background in technology ...
(Date:6/1/2015)... and RARITAN, N.J. , June ... (Janssen) announced data from the Phase 3 multicenter ... progression-free survival (PFS) with trabectedin (YONDELIS ® ) ... (LPS) or leiomyosarcoma (LMS) previously treated with an ... SAR3007 is the largest randomized Phase 3 study ...
Breaking Biology Technology:BioClinica Names David Peters New Chief Financial Officer 2Alere Announces Broad Initiatives to Help Combat Antibiotic Resistance during White House Antibiotic Stewardship Forum 2GenoCAD Announces New Board of Advisors, Improves Protein Expression Using Custom Gene Synthesis 2GenoCAD Announces New Board of Advisors, Improves Protein Expression Using Custom Gene Synthesis 3Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 2Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 3Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 4Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 5Trabectedin Improves Disease Control in Patients with Advanced Soft Tissue Sarcoma 6
... BIOD ) today reported financial results for the ... Quarter Operating Highlights During Biodel,s third quarter of ... 1 testing of two new ultra-rapid-acting formulations of recombinant human ... at Oregon Health and Sciences University who have initiated a ...
... Calif. and TORONTO, Aug. 4, 2011 ... developing a first-in-class anti-apoptosis therapeutic protein known as ... www.generex.com ), a biotechnology company developing a buccal ... in a Phase III trial, today are making ...
... AMSTERDAM, The Netherlands, August 4, 2011 SynCo ... of biopharmaceuticals today announced that its aseptic filling facility is ... first drug product batches for its clients after the expansion ... of the Class A zone is an important milestone in ...
Cached Biology Technology:Biodel Reports Third Quarter Fiscal Year 2011 Financial Results 2Biodel Reports Third Quarter Fiscal Year 2011 Financial Results 3Biodel Reports Third Quarter Fiscal Year 2011 Financial Results 4Biodel Reports Third Quarter Fiscal Year 2011 Financial Results 5Biodel Reports Third Quarter Fiscal Year 2011 Financial Results 6Amarantus BioSciences and Generex Biotechnology Collaborate on Cell Therapy for Late Stage Diabetes 2Amarantus BioSciences and Generex Biotechnology Collaborate on Cell Therapy for Late Stage Diabetes 3Amarantus BioSciences and Generex Biotechnology Collaborate on Cell Therapy for Late Stage Diabetes 4Amarantus BioSciences and Generex Biotechnology Collaborate on Cell Therapy for Late Stage Diabetes 5SynCo Bio Partners Expands the Class A Zone in its Aseptic Filling Facility 2
Agarose-ME, 500 g. Suitable for immunoelectrophoresis.Gel point (1.5%): 36 1.5 C, EEO (-mr): 0.16-0.19, Gel strength (1%): > 1000 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Bio...
... while maintaining high cell viability , ... , Fast: less than one ... , Highly reproducible results from ... with the Bio-Rad Gene Pulser Xcell System ...
100 adhesive strips....
Request Info...
Biology Products: