Navigation Links
Study provides explanation for connection between low birth weight and obesity later in life
Date:3/9/2011

Providing further understanding of the link between low birth weights and obesity later in life, researchers found nutritionally deprived newborns are "programmed" to eat more because they develop less neurons in the region of the brain that controls food intake, according to an article published today in the journal, Brain Research.

The study by a team of researchers at Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) suggests that overeating is programmed at the level of stem cells before birth when the mother has poor or inadequate nutrition.

Using an animal model, the researchers found less division and differentiation of the neural stem cells of a newborn with low birth weight as compared to normal birth weight. Previous studies have found a small size at birth followed by accelerated "catch-up" growth is associated with an increased risk of adult obesity, cardiovascular disease, type 2 diabetes, hypertension and osteoporosis.

"This study demonstrates the importance of maternal nutrition and health in reducing obesity," said Dr. Mina Desai, an LA BioMed principal investigator and corresponding author of the new study. "Obesity and its related diseases are the leading cause of death in our society, yet we have few effective strategies for prevention or treatment. These studies suggest maternal nutrition could play a critical role in preventing obesity and related disease."

In addition to obesity, the findings of altered brain (neural stem cells) development suggest that fetal growth restriction may be associated with cognitive and/or behavioral alterations. Importantly, the study offers potential opportunities for prevention and treatment for obesity and other related disorders. In addition to Dr. Desai, LA BioMed investigators Tie Li and Michael G. Ross participated in the study.

More than 60% of American adults are overweight and more than 1 in 5 are obese. Obesity is a serious health concern for children and adolescents, as well. About 17 percent of children and adolescents ages 2-19 years are obese.


'/>"/>

Contact: Laura Mecoy
Lmecoy@issuesmanagement.com
310-546-5860
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)
Source:Eurekalert  

Related biology news :

1. New UF study shows some sharks follow mental map to navigate seas
2. Study shows how plants sort and eliminate genes over millennia
3. MBARI and Monterey Bay National Marine Sanctuary to study effects of shipping containers lost at sea
4. Rensselaer professor utilizing New York state grant to study adult stem cells
5. Study analyzes role of PARP enzyme in eukaryotes
6. Fossil bird study describes ripple effect of extinction in animal kingdom
7. University of Missouri researcher study provides insight into how corn makes hormones
8. Rainwater harvest study finds roofing material affects water quality
9. A study reveals the keys to the locomotion of snails
10. Pathology study tracks uterine changes with mifepristone
11. David and Goliath viruses shed light on the origin of jumping genes: UBC study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study provides explanation for connection between low birth weight and obesity later in life
(Date:11/17/2016)... Global Market Watch: Primarily supported by ownership types; ... Academics) market is to witness a value of US$37.1 billion ... Compounded Annual Growth Rate (CAGR) of 10.75% is foreseen from ... 2014-2020. North America is not way ... Europe at 9.56% respectively. Report Focus: ...
(Date:11/15/2016)... , Nov. 15, 2016  Synthetic Biologics, Inc. ... therapeutics focused on the gut microbiome, today announced ... 25,000,000 shares of its common stock and warrants ... at a price to the public of $1.00 ... Synthetic Biologics from the offering, excluding the proceeds, ...
(Date:11/14/2016)... SANTA CLARA, Calif. , Nov. 14, ... of the biometric identification market, Frost & ... Global Frost & Sullivan Award for Visionary ... leading player in the biometric identification market ... a multi-modal verification solution for instant, seamless, ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... ... 01, 2016 , ... DrugDev believes the only way to achieve ... experience. All three tenets were on display at the 2nd Annual DrugDev User Summit ... sponsor, CRO and site organizations to discuss innovation and the future of clinical research. ...
(Date:12/2/2016)... , ... December 02, 2016 , ... Robots will storm ... on December 3rd, 2016. The event, which is held on the United Nations ... helping Americans with Disabilities back into the workplace. Suitable Technologies is partnering with NTI ...
(Date:12/2/2016)... RICHMOND, BC , Dec. 2, 2016 /PRNewswire/ - bioLytical Laboratories, a world leader ... Test, to Kenya,s Pharmaceutical Association members. (Photo: ... ... , , ... Initiative (CHAI) and the Kenya Pharmaceutical Association (KPA) to introduce the INSTI HIV Self ...
(Date:11/30/2016)... York , November 30, 2016 ... as a few players hold a dominant share in ... Charles River Laboratories International, Inc., and Merck KGaA, held ... in 2015. Transparency Market Research observes that these companies ... focused on development products that are do not require ...
Breaking Biology Technology: