Navigation Links
Study prompts rethink of how ovaries develop
Date:2/11/2013

New research from the University of Adelaide will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility.

The study, now published in the journal PLOS ONE, also names a new type of cell that plays a key role in the development of ovaries and ovarian follicles, which are responsible for the production of eggs in women.

The discovery is expected to prompt further studies around the world to better understand how ovaries and ovarian follicles develop in female fetuses. This could be critical to treating or preventing a range of health conditions in later life, including infertility and ovarian cancer.

"For more than a decade, scientists have believed that ovarian follicle cells are derived from the epithelial cells on the surface of the ovary as it develops," says research leader Professor Ray Rodgers, from the University of Adelaide's Robinson Institute.

"Instead, contrary to conventional thinking, we've found a new cell type that is the precursor to both the cells on the surface of the ovary and the follicular cells. We call this the GREL (Gonadal Ridge Epithelial-Like) cell."

Professor Rodgers says this work could lead to new insights into a range of conditions, such as premature ovarian failure, early menopause, polycystic ovarian syndrome (PCOS) and ovarian cancer.

"The role of the ovarian follicle in many of these conditions is very important," he says. "For example, the PCOS ovary is associated with an increased number of growing follicles that at some point just stop working.

"With early menopause, there is a theory that some women may not have had enough egg-producing ovarian follicles at development, so once their reserve of follicles has been used up earlier, menopause sets in.

"Ovarian cancer is a different story - about 90% of ovarian cancers are of an epithelial type. However, our study has shown us for the first time that when the ovary is first developing, it doesn't have an epithelial layer. Why this is, we're not sure yet."


'/>"/>
Contact: Professor Ray Rodgers, University of Adelaide
ray.rodgers@adelaide.edu.au
61-883-133-932
University of Adelaide
Source:Eurekalert  

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. Law that regulates shark fishery is too liberal: UBC study
3. New study will help protect vulnerable birds from impacts of climate change
4. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
5. BYU study: Using a gun in bear encounters doesnt make you safer
6. 15-year study: When it comes to creating wetlands, Mother Nature is in charge
7. Pycnogenol (French maritime pine bark extract) shown to improve menopause symptoms in new study
8. Crystal structure of archael chromatin clarified in new study
9. EU-funded study underlines importance of Congo Basin for global climate and biodiversity
10. University of Houston study shows BP oil spill hurt marshes, but recovery possible
11. Study demonstrates cells can acquire new functions through transcriptional regulatory network
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study prompts rethink of how ovaries develop
(Date:6/16/2016)... 16, 2016 The global ... to reach USD 1.83 billion by 2024, according ... Inc. Technological proliferation and increasing demand in commercial ... to drive the market growth.      ... The development of advanced multimodal techniques for biometric ...
(Date:6/9/2016)... 9, 2016 Paris Police ... video security solution to ensure the safety of people and ... during the major tournament Teleste, an international technology ... services, announced today that its video security solution will be ... back up public safety across the country. The system roll-out ...
(Date:6/2/2016)... June 2, 2016 The Department of ... awarded the 44 million US Dollar project, for the ... Plates including Personalization, Enrolment, and IT Infrastructure , ... the production and implementation of Identity Management Solutions. Numerous renowned ... Decatur was selected for the most ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" ... by its major shareholders, Clean Technology Fund I, LP ... States based venture capital funds which together ... (on a fully diluted, as converted basis), that they ... their entire equity holdings in Biorem to TUS Holdings ...
(Date:6/27/2016)... ... June 27, 2016 , ... Parallel 6 , the ... today the Clinical Reach Virtual Patient Encounter CONSULT module which enables both ... physician and clinical trial team. , Using the CONSULT module, patients and physicians can ...
(Date:6/27/2016)... PHILADELPHIA , June 27, 2016  Liquid ... today announced the funding of a Sponsored Research ... study circulating tumor cells (CTCs) from cancer patients.  ... changes in CTC levels correlate with clinical outcomes ... therapies. These data will then be employed to ...
(Date:6/24/2016)... , June 24, 2016 Epic ... sensitively detects cancers susceptible to PARP inhibitors by ... tumor cells (CTCs). The new test has already ... therapeutics in multiple cancer types. Over ... DNA damage response pathways, including PARP, ATM, ATR, ...
Breaking Biology Technology: